ENSDARG00000016360


Danio rerio

Features
Gene ID: ENSDARG00000016360
  
Biological name :kpna1
  
Synonyms : karyopherin alpha 1 (importin alpha 5) / kpna1
  
Possible biological names infered from orthology : Importin subunit alpha-5 / karyopherin subunit alpha 1 / P52294 / Q60960
  
Species: Danio rerio
  
Chr. number: 24
Strand: -1
Band:
Gene start: 20941360
Gene end: 20956781
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000120790
NCBI entrez gene - 572542     See in Manteia.
RefSeq - XM_696267
swissprot - F1QB53
ZFIN ID - ZDB-GENE-091116-39
Ensembl - ENSDARG00000016360
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KPNA1ENSGALG00000014426Gallus gallus
 KPNA1ENSG00000114030Homo sapiens
 Kpna1ENSMUSG00000022905Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
kpna5 / karyopherin alpha 5 (importin alpha 6) / O15131* / karyopherin subunit alpha 5*ENSDARG0000004203071
kpna6 / karyopherin alpha 6 (importin alpha 7) / O60684* / O35345* / Importin subunit alpha-7 * / karyopherin subunit alpha 6*ENSDARG0000004498070
kpna4 / karyopherin alpha 4 (importin alpha 3) / O00629* / O35343* / karyopherin subunit alpha 4* / karyopherin (importin) alpha 4*ENSDARG0000002319042
kpna3 / karyopherin alpha 3 (importin alpha 4) / O35344* / O00505* / Importin subunit alpha-4 * / karyopherin subunit alpha 3*ENSDARG0000005264142
kpna2 / karyopherin alpha 2 (RAG cohort 1, importin alpha 1) / P52293* / P52292* / Gm10184* / Importin subunit alpha-1 * / predicted pseudogene 10184* / karyopherin subunit alpha 2*ENSDARG0000003806640
kpna7 / karyopherin alpha 7 (importin alpha 8) / A9QM74* / karyopherin subunit alpha 7*ENSDARG0000002716938


Protein motifs (from Interpro)
Interpro ID Name
 IPR000225  Armadillo
 IPR002652  Importin-alpha, importin-beta-binding domain
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR024931  Importin subunit alpha
 IPR032413  Atypical Arm repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006606 protein import into nucleus IEA
 biological_processGO:0006607 NLS-bearing protein import into nucleus IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005643 nuclear pore IBA
 cellular_componentGO:0005654 nucleoplasm IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0008139 nuclear localization sequence binding IBA
 molecular_functionGO:0008565 protein transporter activity IBA
 molecular_functionGO:0061608 nuclear import signal receptor activity IEA


Pathways (from Reactome)
Pathway description
Activation of DNA fragmentation factor


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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