ENSGALG00000014426


Gallus gallus

Features
Gene ID: ENSGALG00000014426
  
Biological name :KPNA1
  
Synonyms : Importin subunit alpha-5 / KPNA1 / Q5ZML1
  
Possible biological names infered from orthology : karyopherin subunit alpha 1 / P52294 / Q60960
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 76808272
Gene end: 76859608
  
Corresponding Affymetrix probe sets: GgaAffx.11476.1.S1_at (Chicken Array)   GgaAffx.9161.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000034376
NCBI entrez gene - 418271     See in Manteia.
RefSeq - NM_001030774
RefSeq Peptide - NP_001025945
swissprot - Q5ZML1
Ensembl - ENSGALG00000014426
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kpna1ENSDARG00000016360Danio rerio
 KPNA1ENSG00000114030Homo sapiens
 Kpna1ENSMUSG00000022905Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KPNA5 / karyopherin subunit alpha 5 / O15131*ENSGALG0000001493780
KPNA6 / karyopherin subunit alpha 6 / O35345* / O60684* / Importin subunit alpha-7 *ENSGALG0000000338380
KPNA4 / karyopherin subunit alpha 4 / O00629* / O35343* / karyopherin (importin) alpha 4*ENSGALG0000000954947
KPNA3 / karyopherin subunit alpha 3 / O00505* / O35344* / Importin subunit alpha-4 *ENSGALG0000001700947
KPNA2 / importin subunit alpha-1 / P52292* / P52293* / Gm10184* / predicted pseudogene 10184* / karyopherin subunit alpha 2*ENSGALG0000000358446
KPNA7 / karyopherin subunit alpha 7 / A9QM74* / C0LLJ0* / Importin subunit alpha-8 *ENSGALG0000000466540


Protein motifs (from Interpro)
Interpro ID Name
 IPR000225  Armadillo
 IPR002652  Importin-alpha, importin-beta-binding domain
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR024931  Importin subunit alpha
 IPR032413  Atypical Arm repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006606 protein import into nucleus IEA
 biological_processGO:0006607 NLS-bearing protein import into nucleus IBA
 biological_processGO:0015031 protein transport IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005643 nuclear pore IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0030425 dendrite ISS
 molecular_functionGO:0008139 nuclear localization sequence binding IBA
 molecular_functionGO:0008565 protein transporter activity IBA
 molecular_functionGO:0061608 nuclear import signal receptor activity IEA


Pathways (from Reactome)
Pathway description
Activation of DNA fragmentation factor


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002820 DFFA / DNA fragmentation factor subunit alpha / O00273* / O54786*  / complex / reaction
 ENSGALG00000036295 DFFB / DNA fragmentation factor subunit beta / O54788* / O76075*  / reaction / complex






 

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