ENSGALG00000003584


Gallus gallus

Features
Gene ID: ENSGALG00000003584
  
Biological name :KPNA2
  
Synonyms : importin subunit alpha-1 / KPNA2
  
Possible biological names infered from orthology : Gm10184 / karyopherin subunit alpha 2 / P52292 / P52293 / predicted pseudogene 10184
  
Species: Gallus gallus
  
Chr. number: 18
Strand: -1
Band:
Gene start: 7053034
Gene end: 7058678
  
Corresponding Affymetrix probe sets: GgaAffx.11578.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005662
Ensembl peptide - ENSGALP00000063459
Ensembl peptide - ENSGALP00000047927
NCBI entrez gene - 417420     See in Manteia.
RefSeq - NM_001006209
RefSeq - XM_015279891
RefSeq Peptide - NP_001006209
swissprot - A0A1L1RX89
swissprot - A0A1D5P5F9
swissprot - F1NJS6
Ensembl - ENSGALG00000003584
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kpna2ENSDARG00000038066Danio rerio
 KPNA2ENSG00000182481Homo sapiens
 Kpna2ENSMUSG00000018362Mus musculus
 P52293ENSMUSG00000066878Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KPNA7 / karyopherin subunit alpha 7 / A9QM74* / C0LLJ0* / Importin subunit alpha-8 *ENSGALG0000000466559
KPNA4 / karyopherin subunit alpha 4 / O00629* / O35343* / karyopherin (importin) alpha 4*ENSGALG0000000954951
KPNA3 / karyopherin subunit alpha 3 / O00505* / O35344* / Importin subunit alpha-4 *ENSGALG0000001700950
KPNA5 / karyopherin subunit alpha 5 / O15131*ENSGALG0000001493747
KPNA1 / Q5ZML1 / Importin subunit alpha-5 / P52294* / Q60960* / karyopherin subunit alpha 1*ENSGALG0000001442647
KPNA6 / karyopherin subunit alpha 6 / O35345* / O60684* / Importin subunit alpha-7 *ENSGALG0000000338346


Protein motifs (from Interpro)
Interpro ID Name
 IPR000225  Armadillo
 IPR002652  Importin-alpha, importin-beta-binding domain
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR024931  Importin subunit alpha
 IPR032413  Atypical Arm repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006606 protein import into nucleus IEA
 biological_processGO:0006607 NLS-bearing protein import into nucleus IEA
 biological_processGO:0015031 protein transport IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005643 nuclear pore IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0008139 nuclear localization sequence binding IEA
 molecular_functionGO:0008565 protein transporter activity IEA
 molecular_functionGO:0042826 histone deacetylase binding IEA
 molecular_functionGO:0061608 nuclear import signal receptor activity IEA


Pathways (from Reactome)
Pathway description
Sensing of DNA Double Strand Breaks


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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