ENSMUSG00000066878


Mus musculus

Features
Gene ID: ENSMUSG00000066878
  
Biological name :Gm10184
  
Synonyms : Gm10184 / P52293 / predicted pseudogene 10184
  
Possible biological names infered from orthology : karyopherin subunit alpha 2 / KPNA2 / P52292
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: E5
Gene start: 89908511
Gene end: 89910449
  
Corresponding Affymetrix probe sets: 10392284 (MoGene1.0st)   10453512 (MoGene1.0st)   10497503 (MoGene1.0st)   1415860_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000137310
MGI - MGI:3704480
swissprot - P52293
swissprot - Q52L97
Ensembl - ENSMUSG00000066878
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kpna2ENSDARG00000038066Danio rerio
 KPNA2ENSGALG00000003584Gallus gallus
 KPNA2ENSG00000182481Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kpna2 / P52293 / Importin subunit alpha-1 / P52292* / karyopherin subunit alpha 2*ENSMUSG00000018362100
Kpna4 / O35343 / karyopherin (importin) alpha 4 / O00629* / karyopherin subunit alpha 4*ENSMUSG0000002778250
Kpna3 / O35344 / Importin subunit alpha-4 / O00505* / karyopherin subunit alpha 3*ENSMUSG0000002192949
Kpna1 / Q60960 / Importin subunit alpha-5 / P52294* / karyopherin subunit alpha 1*ENSMUSG0000002290547
Kpna6 / O35345 / Importin subunit alpha-7 / O60684* / karyopherin subunit alpha 6*ENSMUSG0000000373147
Kpna7 / C0LLJ0 / Importin subunit alpha-8 / A9QM74* / karyopherin subunit alpha 7*ENSMUSG0000003877046


Protein motifs (from Interpro)
Interpro ID Name
 IPR000225  Armadillo
 IPR002652  Importin-alpha, importin-beta-binding domain
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR024931  Importin subunit alpha
 IPR032413  Atypical Arm repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006606 protein import into nucleus IDA
 biological_processGO:0006607 NLS-bearing protein import into nucleus ISO
 biological_processGO:0015031 protein transport IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005643 nuclear pore IBA
 cellular_componentGO:0005654 nucleoplasm IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008139 nuclear localization sequence binding ISO
 molecular_functionGO:0008565 protein transporter activity IDA
 molecular_functionGO:0042826 histone deacetylase binding ISO
 molecular_functionGO:0061608 nuclear import signal receptor activity IEA
 molecular_functionGO:0070491 repressing transcription factor binding IPI


Pathways (from Reactome)
Pathway description
Sensing of DNA Double Strand Breaks


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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