ENSDARG00000038066


Danio rerio

Features
Gene ID: ENSDARG00000038066
  
Biological name :kpna2
  
Synonyms : karyopherin alpha 2 (RAG cohort 1, importin alpha 1) / kpna2
  
Possible biological names infered from orthology : Gm10184 / Importin subunit alpha-1 / karyopherin subunit alpha 2 / P52292 / P52293 / predicted pseudogene 10184
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 25369965
Gene end: 25377163
  
Corresponding Affymetrix probe sets: Dr.1691.4.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000055489
NCBI entrez gene - 436607     See in Manteia.
RefSeq - NM_001002335
RefSeq Peptide - NP_001002335
swissprot - F1QG82
ZFIN ID - ZDB-GENE-040718-22
Ensembl - ENSDARG00000038066
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KPNA2ENSGALG00000003584Gallus gallus
 KPNA2ENSG00000182481Homo sapiens
 Kpna2ENSMUSG00000018362Mus musculus
 P52293ENSMUSG00000066878Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
kpna7 / karyopherin alpha 7 (importin alpha 8) / A9QM74* / karyopherin subunit alpha 7*ENSDARG0000002716958
kpna3 / karyopherin alpha 3 (importin alpha 4) / O35344* / O00505* / Importin subunit alpha-4 * / karyopherin subunit alpha 3*ENSDARG0000005264149
kpna4 / karyopherin alpha 4 (importin alpha 3) / O00629* / O35343* / karyopherin subunit alpha 4* / karyopherin (importin) alpha 4*ENSDARG0000002319048
kpna6 / karyopherin alpha 6 (importin alpha 7) / O60684* / O35345* / Importin subunit alpha-7 * / karyopherin subunit alpha 6*ENSDARG0000004498047
kpna5 / karyopherin alpha 5 (importin alpha 6) / O15131* / karyopherin subunit alpha 5*ENSDARG0000004203046
kpna1 / karyopherin alpha 1 (importin alpha 5) / Q60960* / P52294* / Importin subunit alpha-5 * / karyopherin subunit alpha 1*ENSDARG0000001636045


Protein motifs (from Interpro)
Interpro ID Name
 IPR000225  Armadillo
 IPR002652  Importin-alpha, importin-beta-binding domain
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR024931  Importin subunit alpha
 IPR032413  Atypical Arm repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006606 protein import into nucleus IEA
 biological_processGO:0006607 NLS-bearing protein import into nucleus IBA
 biological_processGO:0015031 protein transport IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005643 nuclear pore IBA
 cellular_componentGO:0005654 nucleoplasm IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0008139 nuclear localization sequence binding IBA
 molecular_functionGO:0008565 protein transporter activity IBA
 molecular_functionGO:0061608 nuclear import signal receptor activity IEA


Pathways (from Reactome)
Pathway description
Sensing of DNA Double Strand Breaks


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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