ENSMUSG00000021929


Mus musculus

Features
Gene ID: ENSMUSG00000021929
  
Biological name :Kpna3
  
Synonyms : Importin subunit alpha-4 / Kpna3 / O35344
  
Possible biological names infered from orthology : karyopherin subunit alpha 3 / O00505
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: D1
Gene start: 61365211
Gene end: 61439874
  
Corresponding Affymetrix probe sets: 10420637 (MoGene1.0st)   1421828_at (Mouse Genome 430 2.0 Array)   1450385_at (Mouse Genome 430 2.0 Array)   1450386_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022496
NCBI entrez gene - 16648     See in Manteia.
MGI - MGI:1100863
RefSeq - NM_008466
RefSeq Peptide - NP_032492
swissprot - O35344
swissprot - Q543M7
Ensembl - ENSMUSG00000021929
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kpna3ENSDARG00000052641Danio rerio
 KPNA3ENSGALG00000017009Gallus gallus
 KPNA3ENSG00000102753Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kpna4 / O35343 / karyopherin (importin) alpha 4 / O00629* / karyopherin subunit alpha 4*ENSMUSG0000002778286
P52293 / Gm10184 / predicted pseudogene 10184 / KPNA2* / P52292* / karyopherin subunit alpha 2*ENSMUSG0000006687850
Kpna2 / P52293 / Importin subunit alpha-1 / P52292* / karyopherin subunit alpha 2*ENSMUSG0000001836250
Kpna1 / Q60960 / Importin subunit alpha-5 / P52294* / karyopherin subunit alpha 1*ENSMUSG0000002290548
Kpna6 / O35345 / Importin subunit alpha-7 / O60684* / karyopherin subunit alpha 6*ENSMUSG0000000373148
Kpna7 / C0LLJ0 / Importin subunit alpha-8 / A9QM74* / karyopherin subunit alpha 7*ENSMUSG0000003877038


Protein motifs (from Interpro)
Interpro ID Name
 IPR000225  Armadillo
 IPR002652  Importin-alpha, importin-beta-binding domain
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR024931  Importin subunit alpha
 IPR032413  Atypical Arm repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006606 protein import into nucleus IEA
 biological_processGO:0006607 NLS-bearing protein import into nucleus IBA
 biological_processGO:0015031 protein transport IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005643 nuclear pore IBA
 cellular_componentGO:0005654 nucleoplasm IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IPI
 molecular_functionGO:0008139 nuclear localization sequence binding IBA
 molecular_functionGO:0008565 protein transporter activity IBA
 molecular_functionGO:0061608 nuclear import signal receptor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Kpna6Gt(AJ0609)Wtsi/Kpna6Gt(AJ0609)Wtsi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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