ENSMUSG00000027782


Mus musculus

Features
Gene ID: ENSMUSG00000027782
  
Biological name :Kpna4
  
Synonyms : karyopherin (importin) alpha 4 / Kpna4 / O35343
  
Possible biological names infered from orthology : karyopherin subunit alpha 4 / O00629
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: E1
Gene start: 69067149
Gene end: 69127113
  
Corresponding Affymetrix probe sets: 10498623 (MoGene1.0st)   1417974_at (Mouse Genome 430 2.0 Array)   1417975_at (Mouse Genome 430 2.0 Array)   1455680_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029353
Ensembl peptide - ENSMUSP00000141227
Ensembl peptide - ENSMUSP00000121076
NCBI entrez gene - 16649     See in Manteia.
MGI - MGI:1100848
RefSeq - NM_008467
RefSeq Peptide - NP_032493
swissprot - A0A0B4J1E7
swissprot - D3YTN1
swissprot - O35343
swissprot - Q4FJX1
Ensembl - ENSMUSG00000027782
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kpna4ENSDARG00000023190Danio rerio
 KPNA4ENSGALG00000009549Gallus gallus
 KPNA4ENSG00000186432Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kpna3 / O35344 / Importin subunit alpha-4 / O00505* / karyopherin subunit alpha 3*ENSMUSG0000002192986
P52293 / Gm10184 / predicted pseudogene 10184 / KPNA2* / P52292* / karyopherin subunit alpha 2*ENSMUSG0000006687851
Kpna2 / P52293 / Importin subunit alpha-1 / P52292* / karyopherin subunit alpha 2*ENSMUSG0000001836251
Kpna6 / O35345 / Importin subunit alpha-7 / O60684* / karyopherin subunit alpha 6*ENSMUSG0000000373149
Kpna1 / Q60960 / Importin subunit alpha-5 / P52294* / karyopherin subunit alpha 1*ENSMUSG0000002290548
Kpna7 / C0LLJ0 / Importin subunit alpha-8 / A9QM74* / karyopherin subunit alpha 7*ENSMUSG0000003877039


Protein motifs (from Interpro)
Interpro ID Name
 IPR000225  Armadillo
 IPR002652  Importin-alpha, importin-beta-binding domain
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR024931  Importin subunit alpha
 IPR032413  Atypical Arm repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006606 protein import into nucleus IDA
 biological_processGO:0006607 NLS-bearing protein import into nucleus IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0042542 response to hydrogen peroxide IMP
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005643 nuclear pore IBA
 cellular_componentGO:0005654 nucleoplasm IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0031965 nuclear membrane IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008139 nuclear localization sequence binding IBA
 molecular_functionGO:0008565 protein transporter activity IDA
 molecular_functionGO:0061608 nuclear import signal receptor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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