ENSGALG00000002820


Gallus gallus

Features
Gene ID: ENSGALG00000002820
  
Biological name :DFFA
  
Synonyms : DFFA / DNA fragmentation factor subunit alpha
  
Possible biological names infered from orthology : O00273 / O54786
  
Species: Gallus gallus
  
Chr. number: 21
Strand: -1
Band:
Gene start: 3732186
Gene end: 3735823
  
Corresponding Affymetrix probe sets: GgaAffx.1822.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004446
Ensembl peptide - ENSGALP00000062346
Ensembl peptide - ENSGALP00000058712
NCBI entrez gene - 419451     See in Manteia.
RefSeq - XM_015297166
RefSeq - XM_417610
swissprot - A0A1L1RU42
swissprot - A0A1L1RIY5
swissprot - F1NBS6
Ensembl - ENSGALG00000002820
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dffaENSDARG00000055770Danio rerio
 DFFAENSG00000160049Homo sapiens
 DffaENSMUSG00000028974Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003508  CIDE-N domain
 IPR015121  DNA fragmentation factor 45kDa, middle domain
 IPR017299  DNA fragmentation factor subunit alpha
 IPR027296  DNA fragmentation factor 45kDa, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0032076 negative regulation of deoxyribonuclease activity IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0061077 chaperone-mediated protein folding IEA
 biological_processGO:0070242 thymocyte apoptotic process IEA
 biological_processGO:1900118 negative regulation of execution phase of apoptosis IBA
 biological_processGO:1902511 negative regulation of apoptotic DNA fragmentation IEA
 cellular_componentGO:0000790 nuclear chromatin IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0044183 protein binding involved in protein folding IEA
 molecular_functionGO:0060703 deoxyribonuclease inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Activation of DNA fragmentation factor


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002820 DFFA / DNA fragmentation factor subunit alpha / O00273* / O54786*  / reaction / complex
 ENSGALG00000014426 KPNA1 / Q5ZML1 / Importin subunit alpha-5 / P52294* / Q60960* / karyopherin subunit alpha 1*  / complex / reaction
 ENSGALG00000010638 CASP3 / caspase 3 / P42574* / P70677* / Caspase-3 Caspase-3 subunit p17 Caspase-3 subunit p12*  / reaction
 ENSGALG00000036295 DFFB / DNA fragmentation factor subunit beta / O54788* / O76075*  / complex / reaction






 

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