ENSDARG00000016496


Danio rerio

Features
Gene ID: ENSDARG00000016496
  
Biological name :cdk8
  
Synonyms : cdk8 / cyclin-dependent kinase 8
  
Possible biological names infered from orthology : P49336 / Q8R3L8
  
Species: Danio rerio
  
Chr. number: 24
Strand: 1
Band:
Gene start: 21514283
Gene end: 21539344
  
Corresponding Affymetrix probe sets: Dr.18577.1.S1_at (Zebrafish Array)   Dr.18577.1.S2_at (Zebrafish Array)   NM_194408_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000022588
NCBI entrez gene - 373868     See in Manteia.
RefSeq - NM_194408
RefSeq - XM_005162678
RefSeq Peptide - NP_919389
swissprot - A8E4S2
ZFIN ID - ZDB-GENE-030903-2
Ensembl - ENSDARG00000016496
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CDK8ENSGALG00000017104Gallus gallus
 CDK8ENSG00000132964Homo sapiens
 Cdk8ENSMUSG00000029635Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cdk19 / cyclin-dependent kinase 19 / Q8BWD8* / Q9BWU1*ENSDARG0000004385881


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Generic Transcription Pathway
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000036096 smad3a / SMAD family member 3a / SMAD3* / Q8BUN5* / P84022* / SMAD family member 3* / Mothers against decapentaplegic homolog 3 *  / reaction
 ENSDARG00000075226 smad4a / SMAD family member 4a / SMAD4* / Q13485* / SMAD family member 4*  / reaction
 ENSDARG00000006389 smad2 / Q9I9P9 / SMAD family member 2 / Q62432* / Q15796* / Mothers against decapentaplegic homolog 2 *  / reaction






 

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