ENSGALG00000017104


Gallus gallus

Features
Gene ID: ENSGALG00000017104
  
Biological name :CDK8
  
Synonyms : CDK8 / cyclin dependent kinase 8
  
Possible biological names infered from orthology : P49336 / Q8R3L8
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 176641567
Gene end: 176691688
  
Corresponding Affymetrix probe sets: Gga.18915.1.S1_at (Chicken Array)   Gga.18915.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000027576
NCBI entrez gene - 428080     See in Manteia.
RefSeq - XM_004938783
RefSeq - XM_015278994
RefSeq - XM_425638
swissprot - E1C2T0
Ensembl - ENSGALG00000017104
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdk8ENSDARG00000016496Danio rerio
 CDK8ENSG00000132964Homo sapiens
 Cdk8ENSMUSG00000029635Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CDK19 / cyclin dependent kinase 19 / Q8BWD8* / Q9BWU1*ENSGALG0000001505183


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IBA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0016592 mediator complex IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004693 cyclin-dependent protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Generic Transcription Pathway
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000014184 SMAD2* / Q15796* / Q62432* / SMAD family member 2* / Mothers against decapentaplegic homolog 2 *  / reaction
 ENSGALG00000036001 SMAD2Z / SMAD2* / Q62432* / Q15796* / SMAD family member 2* / Mothers against decapentaplegic homolog 2 *  / reaction
 ENSGALG00000015471 CCNC / P55168 / Cyclin-C / P24863* / Q62447*  / complex






 

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