ENSDARG00000018266


Danio rerio

Features
Gene ID: ENSDARG00000018266
  
Biological name :mthfd1a
  
Synonyms : methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1a, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase / mthfd1a
  
Possible biological names infered from orthology : methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 / methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase / MTHFD1 / P11586 / Q922D8
  
Species: Danio rerio
  
Chr. number: 20
Strand: 1
Band:
Gene start: 27646772
Gene end: 27687457
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000120805
Ensembl peptide - ENSDARP00000146429
Ensembl peptide - ENSDARP00000150792
NCBI entrez gene - 567587     See in Manteia.
swissprot - Q5RIH2
ZFIN ID - ZDB-GENE-041001-127
Ensembl - ENSDARG00000018266
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MTHFD1ENSGALG00000011797Gallus gallus
 MTHFD1ENSG00000100714Homo sapiens
 Mthfd1ENSMUSG00000021048Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mthfd1b / methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b / Q922D8* / MTHFD1* / P11586* / methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate syn...ENSDARG0000004049261
mthfd1l / methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like / Q3V3R1* / Q6UB35*ENSDARG0000004222139


Protein motifs (from Interpro)
Interpro ID Name
 IPR000559  Formate-tetrahydrofolate ligase, FTHFS
 IPR000672  Tetrahydrofolate dehydrogenase/cyclohydrolase
 IPR016040  NAD(P)-binding domain
 IPR020630  Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
 IPR020631  Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
 IPR020867  Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004329 formate-tetrahydrofolate ligase activity IEA
 molecular_functionGO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Metabolism of folate and pterines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000018266 mthfd1a / methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1a, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase / Q922D8* / MTHFD1* / P11586* / methylenet...  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr