ENSDARG00000018967


Danio rerio

Features
Gene ID: ENSDARG00000018967
  
Biological name :gabbr1a
  
Synonyms : gabbr1a / gamma-aminobutyric acid (GABA) B receptor, 1a
  
Possible biological names infered from orthology : GABBR1 / gamma-aminobutyric acid type B receptor subunit 1 / Q9UBS5 / Q9WV18
  
Species: Danio rerio
  
Chr. number: 15
Strand: -1
Band:
Gene start: 34717514
Gene end: 34845414
  
Corresponding Affymetrix probe sets: DrAffx.2.17.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000004577
Ensembl peptide - ENSDARP00000128430
swissprot - F1RDY7
swissprot - X1WDY0
ZFIN ID - ZDB-GENE-030904-5
Ensembl - ENSDARG00000018967
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GABBR1ENSG00000204681Homo sapiens
 Gabbr1ENSMUSG00000024462Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gabbr1b / gamma-aminobutyric acid (GABA) B receptor, 1b / GABBR1* / Q9UBS5* / Q9WV18* / gamma-aminobutyric acid type B receptor subunit 1*ENSDARG0000001666783
gabbr2 / gamma-aminobutyric acid (GABA) B receptor, 2 / O75899* / Q80T41* / gamma-aminobutyric acid type B receptor subunit 2*ENSDARG0000006104225
gpr156 / G protein-coupled receptor 156 / Q8NFN8*ENSDARG000000862157
CR855311.5ENSDARG000001117955


Protein motifs (from Interpro)
Interpro ID Name
 IPR000337  GPCR, family 3
 IPR000436  Sushi/SCR/CCP domain
 IPR001828  Receptor, ligand binding region
 IPR002455  GPCR family 3, GABA-B receptor
 IPR002456  GPCR family 3, gamma-aminobutyric acid receptor, type B1
 IPR017978  GPCR family 3, C-terminal
 IPR028082  Periplasmic binding protein-like I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004965 G-protein coupled GABA receptor activity IEA


Pathways (from Reactome)
Pathway description
Activation of G protein gated Potassium channels
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
GABA B receptor activation
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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