ENSDARG00000061042


Danio rerio

Features
Gene ID: ENSDARG00000061042
  
Biological name :gabbr2
  
Synonyms : gabbr2 / gamma-aminobutyric acid (GABA) B receptor, 2
  
Possible biological names infered from orthology : gamma-aminobutyric acid type B receptor subunit 2 / O75899 / Q80T41
  
Species: Danio rerio
  
Chr. number: 19
Strand: 1
Band:
Gene start: 34311374
Gene end: 34679738
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000081052
NCBI entrez gene - 560267     See in Manteia.
RefSeq - NM_001144043
RefSeq Peptide - NP_001137515
swissprot - Q1LUN9
ZFIN ID - ZDB-GENE-060503-620
Ensembl - ENSDARG00000061042
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GABBR2ENSGALG00000013200Gallus gallus
 GABBR2ENSG00000136928Homo sapiens
 Gabbr2ENSMUSG00000039809Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gabbr1b / gamma-aminobutyric acid (GABA) B receptor, 1b / GABBR1* / Q9UBS5* / Q9WV18* / gamma-aminobutyric acid type B receptor subunit 1*ENSDARG0000001666727
gabbr1a / gamma-aminobutyric acid (GABA) B receptor, 1a / GABBR1* / Q9UBS5* / Q9WV18* / gamma-aminobutyric acid type B receptor subunit 1*ENSDARG0000001896726
gpr156 / G protein-coupled receptor 156 / Q8NFN8*ENSDARG000000862158
CR855311.5ENSDARG000001117955


Protein motifs (from Interpro)
Interpro ID Name
 IPR000337  GPCR, family 3
 IPR001828  Receptor, ligand binding region
 IPR002455  GPCR family 3, GABA-B receptor
 IPR002457  GPCR family 3, gamma-aminobutyric acid receptor, type B2
 IPR017978  GPCR family 3, C-terminal
 IPR017979  GPCR, family 3, conserved site
 IPR028082  Periplasmic binding protein-like I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004965 G-protein coupled GABA receptor activity IEA


Pathways (from Reactome)
Pathway description
Activation of G protein gated Potassium channels
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
GABA B receptor activation
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000019418 kcnj2a / potassium inwardly-rectifying channel, subfamily J, member 2a / KCNJ2* / P63252* / P35561* / potassium voltage-gated channel subfamily J member 2* / potassium inwardly-rectifying c...  / complex
 ENSDARG00000058985 KCNJ6 / potassium voltage-gated channel subfamily J member 6 / P48051*  / complex
 ENSDARG00000035357 gnb2 / guanine nucleotide binding protein (G protein), beta polypeptide 2 / P62880* / P62879* / G protein subunit beta 2* / guanine nucleotide binding protein (G protein), beta 2*  / complex
 ENSDARG00000002696 gnb3b / guanine nucleotide binding protein (G protein), beta polypeptide 3b / GNB3* / Q61011* / P16520* / G protein subunit beta 3* / guanine nucleotide binding protein (G protein), beta 3*  / complex
 ENSDARG00000090454 gnb1a / Q6PH57 / guanine nucleotide binding protein (G protein), beta polypeptide 1a / GNB1* / P62873* / G protein subunit beta 1*  / complex
 ENSDARG00000016667 gabbr1b / gamma-aminobutyric acid (GABA) B receptor, 1b / GABBR1* / Q9UBS5* / Q9WV18* / gamma-aminobutyric acid type B receptor subunit 1*  / complex
 ENSDARG00000104372 gnb1b / guanine nucleotide binding protein (G protein), beta polypeptide 1b / GNB1* / P62874* / P62873* / G protein subunit beta 1* / guanine nucleotide binding protein (G protein), beta 1*  / complex
 ENSDARG00000004358 gnb3a / guanine nucleotide binding protein (G protein), beta polypeptide 3a / GNB3* / Q61011* / P16520* / G protein subunit beta 3* / guanine nucleotide binding protein (G protein), beta 3*  / complex
 ENSDARG00000062217 kcnj3b / potassium inwardly-rectifying channel, subfamily J, member 3b / KCNJ3* / P48549* / P63250* / potassium voltage-gated channel subfamily J member 3* / G protein-activated inward rect...  / complex
 ENSDARG00000058988 KCNJ15 / potassium voltage-gated channel subfamily J member 15 / Q99712*  / complex
 ENSDARG00000077165 kcnj3a / potassium inwardly-rectifying channel, subfamily J, member 3a / KCNJ3* / P48549* / P63250* / potassium voltage-gated channel subfamily J member 3* / G protein-activated inward rect...  / complex
 ENSDARG00000061014 kcnj5 / potassium inwardly-rectifying channel, subfamily J, member 5 / P48544* / P48545* / potassium voltage-gated channel subfamily J member 5* / G protein-activated inward rectifier potas...  / complex
 ENSDARG00000090815 kcnj10a / potassium inwardly-rectifying channel, subfamily J, member 10a / Q9JM63* / KCNJ10* / P78508* / ATP-sensitive inward rectifier potassium channel 10 * / potassium voltage-gated chan...  / complex
 ENSDARG00000105022 FO704813.1 / KCNJ10* / P78508* / potassium voltage-gated channel subfamily J member 10*  / complex
 ENSDARG00000104965 kcnj12a / potassium inwardly-rectifying channel, subfamily J, member 12a / KCNJ18* / P52187* / Q14500* / B7U540* / KCNJ12* / ATP-sensitive inward rectifier potassium channel 12 * / potassiu...  / complex
 ENSDARG00000104389 kcnj2b / potassium inwardly-rectifying channel, subfamily J, member 2b / KCNJ2* / P63252* / P35561* / potassium voltage-gated channel subfamily J member 2* / potassium inwardly-rectifying c...  / complex






 

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