ENSDARG00000090815


Danio rerio

Features
Gene ID: ENSDARG00000090815
  
Biological name :kcnj10a
  
Synonyms : kcnj10a / potassium inwardly-rectifying channel, subfamily J, member 10a
  
Possible biological names infered from orthology : ATP-sensitive inward rectifier potassium channel 10 / KCNJ10 / P78508 / potassium voltage-gated channel subfamily J member 10 / Q9JM63
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 6564653
Gene end: 6604623
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000134949
Ensembl peptide - ENSDARP00000142361
NCBI entrez gene - 100538267     See in Manteia.
swissprot - A0A0G2KRC3
swissprot - E7FD27
ZFIN ID - ZDB-GENE-130726-1
Ensembl - ENSDARG00000090815
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KCNJ10ENSG00000177807Homo sapiens
 Kcnj10ENSMUSG00000044708Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FO704813.1 / KCNJ10* / P78508* / potassium voltage-gated channel subfamily J member 10*ENSDARG0000010502274
KCNJ15 / potassium voltage-gated channel subfamily J member 15 / Q99712*ENSDARG0000005898846
kcnj1b / potassium inwardly-rectifying channel, subfamily J, member 1b / KCNJ1* / O88335* / P48048* / ATP-sensitive inward rectifier potassium channel 1 * / potassium voltage-gated channel ...ENSDARG0000000266637
kcnj12b / potassium inwardly-rectifying channel, subfamily J, member 12bENSDARG0000006261835
kcnj1a.1 / potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1 / KCNJ1* / O88335* / P48048* / ATP-sensitive inward rectifier potassium channel 1 * / potassium ...ENSDARG0000009123235
kcnj1a.2 / potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 2 / KCNJ1* / O88335* / P48048* / ATP-sensitive inward rectifier potassium channel 1 * / potassium ...ENSDARG0000009086635
kcnj1a.6 / potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6 / KCNJ1* / O88335* / P48048* / ATP-sensitive inward rectifier potassium channel 1 * / potassium ...ENSDARG0000008848435
kcnj1a.3 / potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 3 / KCNJ1* / O88335* / P48048* / ATP-sensitive inward rectifier potassium channel 1 * / potassium ...ENSDARG0000008624835
kcnj12a / potassium inwardly-rectifying channel, subfamily J, member 12a / KCNJ18* / P52187* / Q14500* / B7U540* / KCNJ12* / ATP-sensitive inward rectifier potassium channel 12 * / potassiu...ENSDARG0000010496534
kcnj1a.4 / potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 4 / KCNJ1* / O88335* / P48048* / ATP-sensitive inward rectifier potassium channel 1 * / potassium ...ENSDARG0000009063534
kcnj14 / potassium inwardly-rectifying channel, subfamily J, member 14 / Q8JZN3* / Q9UNX9* / ATP-sensitive inward rectifier potassium channel 14 * / potassium voltage-gated channel subfamil...ENSDARG0000007591434
CABZ01079818.1 / KCNJ4* / P48050* / potassium voltage-gated channel subfamily J member 4*ENSDARG0000006811034
kcnj1a.5 / potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 5 / KCNJ1* / O88335* / P48048* / ATP-sensitive inward rectifier potassium channel 1 * / potassium ...ENSDARG0000008906033
KCNJ6 / potassium voltage-gated channel subfamily J member 6 / P48051*ENSDARG0000005898532
kcnj2a / potassium inwardly-rectifying channel, subfamily J, member 2a / KCNJ2* / P63252* / P35561* / potassium voltage-gated channel subfamily J member 2* / potassium inwardly-rectifying c...ENSDARG0000001941832
kcnj2b / potassium inwardly-rectifying channel, subfamily J, member 2b / KCNJ2* / P63252* / P35561* / potassium voltage-gated channel subfamily J member 2* / potassium inwardly-rectifying c...ENSDARG0000010438932
kcnj19a / potassium voltage-gated channel subfamily J member 19aENSDARG0000005974731
kcnj19b / potassium voltage-gated channel, subfamily J, member 19bENSDARG0000006267231
kcnj3b / potassium inwardly-rectifying channel, subfamily J, member 3b / KCNJ3* / P48549* / P63250* / potassium voltage-gated channel subfamily J member 3* / G protein-activated inward rect...ENSDARG0000006221731
kcnj8 / potassium inwardly-rectifying channel, subfamily J, member 8 / P97794* / Q15842* / potassium voltage-gated channel subfamily J member 8*ENSDARG0000004558930


Protein motifs (from Interpro)
Interpro ID Name
 IPR003268  Potassium channel, inwardly rectifying, Kir1.1
 IPR003269  Potassium channel, inwardly rectifying, Kir1.2
 IPR013518  Potassium channel, inwardly rectifying, Kir, cytoplasmic
 IPR014756  Immunoglobulin E-set
 IPR016449  Potassium channel, inwardly rectifying, Kir


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001822 kidney development IMP
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0007626 locomotory behavior IMP
 biological_processGO:0008345 larval locomotory behavior IMP
 biological_processGO:0010107 potassium ion import IBA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0036268 swimming IMP
 biological_processGO:0040011 locomotion IMP
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005242 inward rectifier potassium channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0015272 ATP-activated inward rectifier potassium channel activity IBA


Pathways (from Reactome)
Pathway description
Activation of G protein gated Potassium channels
Potassium transport channels
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000076 swim bladder swim bladder absent , abnormal
Show

 ZFA:0000107 eye eye movement quality , abnormal
Show

 ZFA:0000150 pronephric duct pronephric duct dilated , abnormal
Show

 ZFA:0000151 pronephros pronephros decreased functionality , abnormal
Show

 ZFA:0001094 whole organism whole organism increased contractility , abnormal
whole organism movement behavioral quality , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton movement quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000104372 gnb1b / guanine nucleotide binding protein (G protein), beta polypeptide 1b / GNB1* / P62874* / P62873* / G protein subunit beta 1* / guanine nucleotide binding protein (G protein), beta 1*  / complex
 ENSDARG00000061042 gabbr2 / gamma-aminobutyric acid (GABA) B receptor, 2 / O75899* / Q80T41* / gamma-aminobutyric acid type B receptor subunit 2*  / complex
 ENSDARG00000090454 gnb1a / Q6PH57 / guanine nucleotide binding protein (G protein), beta polypeptide 1a / GNB1* / P62873* / G protein subunit beta 1*  / complex
 ENSDARG00000035357 gnb2 / guanine nucleotide binding protein (G protein), beta polypeptide 2 / P62880* / P62879* / G protein subunit beta 2* / guanine nucleotide binding protein (G protein), beta 2*  / complex
 ENSDARG00000002696 gnb3b / guanine nucleotide binding protein (G protein), beta polypeptide 3b / GNB3* / Q61011* / P16520* / G protein subunit beta 3* / guanine nucleotide binding protein (G protein), beta 3*  / complex
 ENSDARG00000016667 gabbr1b / gamma-aminobutyric acid (GABA) B receptor, 1b / GABBR1* / Q9UBS5* / Q9WV18* / gamma-aminobutyric acid type B receptor subunit 1*  / complex
 ENSDARG00000004358 gnb3a / guanine nucleotide binding protein (G protein), beta polypeptide 3a / GNB3* / Q61011* / P16520* / G protein subunit beta 3* / guanine nucleotide binding protein (G protein), beta 3*  / complex
 ENSDARG00000090815 kcnj10a / potassium inwardly-rectifying channel, subfamily J, member 10a / Q9JM63* / KCNJ10* / P78508* / ATP-sensitive inward rectifier potassium channel 10 * / potassium voltage-gated chan...  / complex
 ENSDARG00000104389 kcnj2b / potassium inwardly-rectifying channel, subfamily J, member 2b / KCNJ2* / P63252* / P35561* / potassium voltage-gated channel subfamily J member 2* / potassium inwardly-rectifying c...  / complex
 ENSDARG00000019418 kcnj2a / potassium inwardly-rectifying channel, subfamily J, member 2a / KCNJ2* / P63252* / P35561* / potassium voltage-gated channel subfamily J member 2* / potassium inwardly-rectifying c...  / complex
 ENSDARG00000105022 FO704813.1 / KCNJ10* / P78508* / potassium voltage-gated channel subfamily J member 10*  / complex
 ENSDARG00000104965 kcnj12a / potassium inwardly-rectifying channel, subfamily J, member 12a / KCNJ18* / P52187* / Q14500* / B7U540* / KCNJ12* / ATP-sensitive inward rectifier potassium channel 12 * / potassiu...  / complex






 

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