ENSDARG00000004358


Danio rerio

Features
Gene ID: ENSDARG00000004358
  
Biological name :gnb3a
  
Synonyms : gnb3a / guanine nucleotide binding protein (G protein), beta polypeptide 3a
  
Possible biological names infered from orthology : GNB3 / G protein subunit beta 3 / guanine nucleotide binding protein (G protein), beta 3 / P16520 / Q61011
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 12022543
Gene end: 12049762
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000017443
NCBI entrez gene - 436710     See in Manteia.
RefSeq - XM_021466676
RefSeq - NM_001002437
RefSeq Peptide - NP_001002437
swissprot - Q6DH55
ZFIN ID - ZDB-GENE-040718-134
Ensembl - ENSDARG00000004358
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GNB3ENSGALG00000034438Gallus gallus
 GNB3ENSG00000111664Homo sapiens
 Gnb3ENSMUSG00000023439Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gnb1a / Q6PH57 / guanine nucleotide binding protein (G protein), beta polypeptide 1a / GNB1* / P62873* / G protein subunit beta 1*ENSDARG0000009045474
gnb1b / guanine nucleotide binding protein (G protein), beta polypeptide 1b / GNB1* / P62874* / P62873* / G protein subunit beta 1* / guanine nucleotide binding protein (G protein), beta 1*ENSDARG0000010437274
gnb2 / guanine nucleotide binding protein (G protein), beta polypeptide 2 / P62880* / P62879* / G protein subunit beta 2* / guanine nucleotide binding protein (G protein), beta 2*ENSDARG0000003535772
gnb3b / guanine nucleotide binding protein (G protein), beta polypeptide 3b / GNB3* / Q61011* / P16520* / G protein subunit beta 3* / guanine nucleotide binding protein (G protein), beta 3*ENSDARG0000000269672
gnb4b / guanine nucleotide binding protein (G protein), beta polypeptide 4b / GNB4* / Q9HAV0* / G protein subunit beta 4*ENSDARG0000011538372
GNB4 / G protein subunit beta 4 / Q9HAV0*ENSDARG0000001927851
gnb5b / Q6PBY0 / guanine nucleotide binding protein (G protein), beta 5b / GNB5* / O14775* / P62881* / G protein subunit beta 5* / guanine nucleotide binding protein (G protein), beta 5*ENSDARG0000005537749
gnb5a / A1L271 / guanine nucleotide binding protein (G protein), beta 5a / GNB5* / P62881* / O14775* / G protein subunit beta 5* / guanine nucleotide binding protein (G protein), beta 5*ENSDARG0000009968548
wdr47b / WD repeat domain 47b / WDR47* / O94967* / WD repeat domain 47*ENSDARG0000009975724
wdr47a / WD repeat domain 47a / WDR47* / Q8CGF6* / O94967* / WD repeat domain 47*ENSDARG0000007813624


Protein motifs (from Interpro)
Interpro ID Name
 IPR001632  G-protein, beta subunit
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR016346  Guanine nucleotide-binding protein, beta subunit
 IPR017986  WD40-repeat-containing domain
 IPR020472  G-protein beta WD-40 repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA


Pathways (from Reactome)
Pathway description
Activation of G protein gated Potassium channels
G-protein activation
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000009480 pdcl / phosducin-like / Q13371* / Q9DBX2* / Phosducin-like protein *  / complex
 ENSDARG00000019418 kcnj2a / potassium inwardly-rectifying channel, subfamily J, member 2a / KCNJ2* / P63252* / P35561* / potassium voltage-gated channel subfamily J member 2* / potassium inwardly-rectifying c...  / complex
 ENSDARG00000016667 gabbr1b / gamma-aminobutyric acid (GABA) B receptor, 1b / GABBR1* / Q9UBS5* / Q9WV18* / gamma-aminobutyric acid type B receptor subunit 1*  / complex
 ENSDARG00000058985 KCNJ6 / potassium voltage-gated channel subfamily J member 6 / P48051*  / complex
 ENSDARG00000061042 gabbr2 / gamma-aminobutyric acid (GABA) B receptor, 2 / O75899* / Q80T41* / gamma-aminobutyric acid type B receptor subunit 2*  / complex
 ENSDARG00000062217 kcnj3b / potassium inwardly-rectifying channel, subfamily J, member 3b / KCNJ3* / P48549* / P63250* / potassium voltage-gated channel subfamily J member 3* / G protein-activated inward rect...  / complex
 ENSDARG00000058988 KCNJ15 / potassium voltage-gated channel subfamily J member 15 / Q99712*  / complex
 ENSDARG00000056831 gng2 / guanine nucleotide binding protein (G protein), gamma 2 / P59768* / P63213* / G protein subunit gamma 2*  / complex / reaction
 ENSDARG00000077165 kcnj3a / potassium inwardly-rectifying channel, subfamily J, member 3a / KCNJ3* / P48549* / P63250* / potassium voltage-gated channel subfamily J member 3* / G protein-activated inward rect...  / complex
 ENSDARG00000061014 kcnj5 / potassium inwardly-rectifying channel, subfamily J, member 5 / P48544* / P48545* / potassium voltage-gated channel subfamily J member 5* / G protein-activated inward rectifier potas...  / complex
 ENSDARG00000090815 kcnj10a / potassium inwardly-rectifying channel, subfamily J, member 10a / Q9JM63* / KCNJ10* / P78508* / ATP-sensitive inward rectifier potassium channel 10 * / potassium voltage-gated chan...  / complex
 ENSDARG00000105022 FO704813.1 / KCNJ10* / P78508* / potassium voltage-gated channel subfamily J member 10*  / complex
 ENSDARG00000104965 kcnj12a / potassium inwardly-rectifying channel, subfamily J, member 12a / KCNJ18* / P52187* / Q14500* / B7U540* / KCNJ12* / ATP-sensitive inward rectifier potassium channel 12 * / potassiu...  / complex
 ENSDARG00000104389 kcnj2b / potassium inwardly-rectifying channel, subfamily J, member 2b / KCNJ2* / P63252* / P35561* / potassium voltage-gated channel subfamily J member 2* / potassium inwardly-rectifying c...  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr