ENSDARG00000058985


Danio rerio

Features
Gene ID: ENSDARG00000058985
  
Biological name :KCNJ6
  
Synonyms : KCNJ6 / potassium voltage-gated channel subfamily J member 6
  
Possible biological names infered from orthology : G protein-activated inward rectifier potassium channel 2 isoform Girk2B / P48051
  
Species: Danio rerio
  
Chr. number: 10
Strand: -1
Band:
Gene start: 124995
Gene end: 135432
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000076416
swissprot - F1QR82
Ensembl - ENSDARG00000058985
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KCNJ6ENSGALG00000016054Gallus gallus
 KCNJ6ENSG00000157542Homo sapiens
 Kcnj6ENSMUSG00000043301Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
zgc:162160ENSDARG0000006025971
kcnj5 / potassium inwardly-rectifying channel, subfamily J, member 5 / P48544* / P48545* / potassium voltage-gated channel subfamily J member 5* / G protein-activated inward rectifier potas...ENSDARG0000006101467
kcnj9 / potassium inwardly-rectifying channel, subfamily J, member 9 / P48543* / Q92806* / potassium voltage-gated channel subfamily J member 9*ENSDARG0000006163660
kcnj19a / potassium voltage-gated channel subfamily J member 19aENSDARG0000005974755
kcnj19b / potassium voltage-gated channel, subfamily J, member 19bENSDARG0000006267254
kcnj3a / potassium inwardly-rectifying channel, subfamily J, member 3a / KCNJ3* / P48549* / P63250* / potassium voltage-gated channel subfamily J member 3* / G protein-activated inward rect...ENSDARG0000007716554
kcnj3b / potassium inwardly-rectifying channel, subfamily J, member 3b / KCNJ3* / P48549* / P63250* / potassium voltage-gated channel subfamily J member 3* / G protein-activated inward rect...ENSDARG0000006221753
kcnj12a / potassium inwardly-rectifying channel, subfamily J, member 12a / KCNJ18* / P52187* / Q14500* / B7U540* / KCNJ12* / ATP-sensitive inward rectifier potassium channel 12 * / potassiu...ENSDARG0000010496547
kcnj2a / potassium inwardly-rectifying channel, subfamily J, member 2a / KCNJ2* / P63252* / P35561* / potassium voltage-gated channel subfamily J member 2* / potassium inwardly-rectifying c...ENSDARG0000001941846
CABZ01079818.1 / KCNJ4* / P48050* / potassium voltage-gated channel subfamily J member 4*ENSDARG0000006811046
kcnj12b / potassium inwardly-rectifying channel, subfamily J, member 12bENSDARG0000006261845
kcnj2b / potassium inwardly-rectifying channel, subfamily J, member 2b / KCNJ2* / P63252* / P35561* / potassium voltage-gated channel subfamily J member 2* / potassium inwardly-rectifying c...ENSDARG0000010438945
si:ch211-113j13.2ENSDARG0000004070145
kcnj14 / potassium inwardly-rectifying channel, subfamily J, member 14 / Q8JZN3* / Q9UNX9* / ATP-sensitive inward rectifier potassium channel 14 * / potassium voltage-gated channel subfamil...ENSDARG0000007591444
kcnj11l / potassium inwardly-rectifying channel, subfamily J, member 11, likeENSDARG0000003143841
kcnj8 / potassium inwardly-rectifying channel, subfamily J, member 8 / P97794* / Q15842* / potassium voltage-gated channel subfamily J member 8*ENSDARG0000004558940
kcnj11 / potassium inwardly-rectifying channel, subfamily J, member 11 / Q14654* / Q61743* / ATP-sensitive inward rectifier potassium channel 11 * / potassium voltage-gated channel subfamil...ENSDARG0000005188039
kcnj10a / potassium inwardly-rectifying channel, subfamily J, member 10a / Q9JM63* / KCNJ10* / P78508* / ATP-sensitive inward rectifier potassium channel 10 * / potassium voltage-gated chan...ENSDARG0000009081533
kcnj1a.4 / potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 4 / KCNJ1* / O88335* / P48048* / ATP-sensitive inward rectifier potassium channel 1 * / potassium ...ENSDARG0000009063532
kcnj1a.1 / potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1 / KCNJ1* / O88335* / P48048* / ATP-sensitive inward rectifier potassium channel 1 * / potassium ...ENSDARG0000009123232


Protein motifs (from Interpro)
Interpro ID Name
 IPR003275  Potassium channel, inwardly rectifying, Kir3.2
 IPR013518  Potassium channel, inwardly rectifying, Kir, cytoplasmic
 IPR014756  Immunoglobulin E-set
 IPR016449  Potassium channel, inwardly rectifying, Kir


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0010107 potassium ion import IBA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005242 inward rectifier potassium channel activity IBA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0015467 G-protein activated inward rectifier potassium channel activity IEA


Pathways (from Reactome)
Pathway description
Activation of G protein gated Potassium channels
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000016667 gabbr1b / gamma-aminobutyric acid (GABA) B receptor, 1b / GABBR1* / Q9UBS5* / Q9WV18* / gamma-aminobutyric acid type B receptor subunit 1*  / complex
 ENSDARG00000090454 gnb1a / Q6PH57 / guanine nucleotide binding protein (G protein), beta polypeptide 1a / GNB1* / P62873* / G protein subunit beta 1*  / complex
 ENSDARG00000061042 gabbr2 / gamma-aminobutyric acid (GABA) B receptor, 2 / O75899* / Q80T41* / gamma-aminobutyric acid type B receptor subunit 2*  / complex
 ENSDARG00000062217 kcnj3b / potassium inwardly-rectifying channel, subfamily J, member 3b / KCNJ3* / P48549* / P63250* / potassium voltage-gated channel subfamily J member 3* / G protein-activated inward rect...  / complex
 ENSDARG00000058985 KCNJ6 / potassium voltage-gated channel subfamily J member 6 / P48051*  / complex
 ENSDARG00000061014 kcnj5 / potassium inwardly-rectifying channel, subfamily J, member 5 / P48544* / P48545* / potassium voltage-gated channel subfamily J member 5* / G protein-activated inward rectifier potas...  / complex
 ENSDARG00000002696 gnb3b / guanine nucleotide binding protein (G protein), beta polypeptide 3b / GNB3* / Q61011* / P16520* / G protein subunit beta 3* / guanine nucleotide binding protein (G protein), beta 3*  / complex
 ENSDARG00000104372 gnb1b / guanine nucleotide binding protein (G protein), beta polypeptide 1b / GNB1* / P62874* / P62873* / G protein subunit beta 1* / guanine nucleotide binding protein (G protein), beta 1*  / complex
 ENSDARG00000035357 gnb2 / guanine nucleotide binding protein (G protein), beta polypeptide 2 / P62880* / P62879* / G protein subunit beta 2* / guanine nucleotide binding protein (G protein), beta 2*  / complex
 ENSDARG00000004358 gnb3a / guanine nucleotide binding protein (G protein), beta polypeptide 3a / GNB3* / Q61011* / P16520* / G protein subunit beta 3* / guanine nucleotide binding protein (G protein), beta 3*  / complex
 ENSDARG00000077165 kcnj3a / potassium inwardly-rectifying channel, subfamily J, member 3a / KCNJ3* / P48549* / P63250* / potassium voltage-gated channel subfamily J member 3* / G protein-activated inward rect...  / complex






 

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