ENSDARG00000016667


Danio rerio

Features
Gene ID: ENSDARG00000016667
  
Biological name :gabbr1b
  
Synonyms : gabbr1b / gamma-aminobutyric acid (GABA) B receptor, 1b
  
Possible biological names infered from orthology : GABBR1 / gamma-aminobutyric acid type B receptor subunit 1 / Q9UBS5 / Q9WV18
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 27040533
Gene end: 27261102
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000045615
Ensembl peptide - ENSDARP00000122879
NCBI entrez gene - 558708     See in Manteia.
RefSeq - XM_003200605
RefSeq - XM_005170102
swissprot - F1QAJ3
swissprot - E9QJJ6
ZFIN ID - ZDB-GENE-060503-5
Ensembl - ENSDARG00000016667
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GABBR1ENSG00000204681Homo sapiens
 Gabbr1ENSMUSG00000024462Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gabbr1a / gamma-aminobutyric acid (GABA) B receptor, 1a / GABBR1* / Q9UBS5* / Q9WV18* / gamma-aminobutyric acid type B receptor subunit 1*ENSDARG0000001896782
gabbr2 / gamma-aminobutyric acid (GABA) B receptor, 2 / O75899* / Q80T41* / gamma-aminobutyric acid type B receptor subunit 2*ENSDARG0000006104226
gpr156 / G protein-coupled receptor 156 / Q8NFN8*ENSDARG000000862157
CR855311.5ENSDARG000001117954


Protein motifs (from Interpro)
Interpro ID Name
 IPR000436  Sushi/SCR/CCP domain
 IPR001828  Receptor, ligand binding region
 IPR002455  GPCR family 3, GABA-B receptor
 IPR002456  GPCR family 3, gamma-aminobutyric acid receptor, type B1
 IPR017978  GPCR family 3, C-terminal
 IPR028082  Periplasmic binding protein-like I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0035095 behavioral response to nicotine IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004965 G-protein coupled GABA receptor activity IEA


Pathways (from Reactome)
Pathway description
Activation of G protein gated Potassium channels
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
GABA B receptor activation
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000019418 kcnj2a / potassium inwardly-rectifying channel, subfamily J, member 2a / KCNJ2* / P63252* / P35561* / potassium voltage-gated channel subfamily J member 2* / potassium inwardly-rectifying c...  / complex
 ENSDARG00000090454 gnb1a / Q6PH57 / guanine nucleotide binding protein (G protein), beta polypeptide 1a / GNB1* / P62873* / G protein subunit beta 1*  / complex
 ENSDARG00000035357 gnb2 / guanine nucleotide binding protein (G protein), beta polypeptide 2 / P62880* / P62879* / G protein subunit beta 2* / guanine nucleotide binding protein (G protein), beta 2*  / complex
 ENSDARG00000004358 gnb3a / guanine nucleotide binding protein (G protein), beta polypeptide 3a / GNB3* / Q61011* / P16520* / G protein subunit beta 3* / guanine nucleotide binding protein (G protein), beta 3*  / complex
 ENSDARG00000104372 gnb1b / guanine nucleotide binding protein (G protein), beta polypeptide 1b / GNB1* / P62874* / P62873* / G protein subunit beta 1* / guanine nucleotide binding protein (G protein), beta 1*  / complex
 ENSDARG00000002696 gnb3b / guanine nucleotide binding protein (G protein), beta polypeptide 3b / GNB3* / Q61011* / P16520* / G protein subunit beta 3* / guanine nucleotide binding protein (G protein), beta 3*  / complex
 ENSDARG00000058985 KCNJ6 / potassium voltage-gated channel subfamily J member 6 / P48051*  / complex
 ENSDARG00000061042 gabbr2 / gamma-aminobutyric acid (GABA) B receptor, 2 / O75899* / Q80T41* / gamma-aminobutyric acid type B receptor subunit 2*  / complex
 ENSDARG00000062217 kcnj3b / potassium inwardly-rectifying channel, subfamily J, member 3b / KCNJ3* / P48549* / P63250* / potassium voltage-gated channel subfamily J member 3* / G protein-activated inward rect...  / complex
 ENSDARG00000058988 KCNJ15 / potassium voltage-gated channel subfamily J member 15 / Q99712*  / complex
 ENSDARG00000077165 kcnj3a / potassium inwardly-rectifying channel, subfamily J, member 3a / KCNJ3* / P48549* / P63250* / potassium voltage-gated channel subfamily J member 3* / G protein-activated inward rect...  / complex
 ENSDARG00000061014 kcnj5 / potassium inwardly-rectifying channel, subfamily J, member 5 / P48544* / P48545* / potassium voltage-gated channel subfamily J member 5* / G protein-activated inward rectifier potas...  / complex
 ENSDARG00000090815 kcnj10a / potassium inwardly-rectifying channel, subfamily J, member 10a / Q9JM63* / KCNJ10* / P78508* / ATP-sensitive inward rectifier potassium channel 10 * / potassium voltage-gated chan...  / complex
 ENSDARG00000105022 FO704813.1 / KCNJ10* / P78508* / potassium voltage-gated channel subfamily J member 10*  / complex
 ENSDARG00000104965 kcnj12a / potassium inwardly-rectifying channel, subfamily J, member 12a / KCNJ18* / P52187* / Q14500* / B7U540* / KCNJ12* / ATP-sensitive inward rectifier potassium channel 12 * / potassiu...  / complex
 ENSDARG00000104389 kcnj2b / potassium inwardly-rectifying channel, subfamily J, member 2b / KCNJ2* / P63252* / P35561* / potassium voltage-gated channel subfamily J member 2* / potassium inwardly-rectifying c...  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr