ENSDARG00000099685


Danio rerio

Features
Gene ID: ENSDARG00000099685
  
Biological name :gnb5a
  
Synonyms : A1L271 / gnb5a / guanine nucleotide binding protein (G protein), beta 5a
  
Possible biological names infered from orthology : GNB5 / G protein subunit beta 5 / guanine nucleotide binding protein (G protein), beta 5 / O14775 / P62881
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 4837915
Gene end: 4851181
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000140306
NCBI entrez gene - 562813     See in Manteia.
RefSeq - NM_001080181
RefSeq Peptide - NP_001073650
swissprot - A1L271
ZFIN ID - ZDB-GENE-070112-342
Ensembl - ENSDARG00000099685
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GNB5ENSGALG00000039307Gallus gallus
 GNB5ENSG00000069966Homo sapiens
 Gnb5ENSMUSG00000032192Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gnb5b / Q6PBY0 / guanine nucleotide binding protein (G protein), beta 5b / GNB5* / O14775* / P62881* / G protein subunit beta 5* / guanine nucleotide binding protein (G protein), beta 5*ENSDARG0000005537789
gnb4b / guanine nucleotide binding protein (G protein), beta polypeptide 4b / GNB4* / Q9HAV0* / G protein subunit beta 4*ENSDARG0000011538350
gnb1a / Q6PH57 / guanine nucleotide binding protein (G protein), beta polypeptide 1a / GNB1* / P62873* / G protein subunit beta 1*ENSDARG0000009045450
gnb1b / guanine nucleotide binding protein (G protein), beta polypeptide 1b / GNB1* / P62874* / P62873* / G protein subunit beta 1* / guanine nucleotide binding protein (G protein), beta 1*ENSDARG0000010437250
gnb2 / guanine nucleotide binding protein (G protein), beta polypeptide 2 / P62880* / P62879* / G protein subunit beta 2* / guanine nucleotide binding protein (G protein), beta 2*ENSDARG0000003535749
gnb3a / guanine nucleotide binding protein (G protein), beta polypeptide 3a / GNB3* / Q61011* / P16520* / G protein subunit beta 3* / guanine nucleotide binding protein (G protein), beta 3*ENSDARG0000000435846
gnb3b / guanine nucleotide binding protein (G protein), beta polypeptide 3b / GNB3* / Q61011* / P16520* / G protein subunit beta 3* / guanine nucleotide binding protein (G protein), beta 3*ENSDARG0000000269645
GNB4 / G protein subunit beta 4 / Q9HAV0*ENSDARG0000001927833
wdr47a / WD repeat domain 47a / WDR47* / Q8CGF6* / O94967* / WD repeat domain 47*ENSDARG0000007813627
wdr47b / WD repeat domain 47b / WDR47* / O94967* / WD repeat domain 47*ENSDARG0000009975726


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR016346  Guanine nucleotide-binding protein, beta subunit
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007634 optokinetic behavior IGI
 biological_processGO:0036269 swimming behavior IGI
 biological_processGO:0060047 heart contraction IGI
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA


Pathways (from Reactome)
Pathway description
G-protein activation
Inactivation, recovery and regulation of the phototransduction cascade
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000009480 pdcl / phosducin-like / Q13371* / Q9DBX2* / Phosducin-like protein *  / complex
 ENSDARG00000016584 rgs7a / regulator of G protein signaling 7a / RGS7* / O54829* / P49802* / regulator of G protein signaling 7*  / reaction / complex
 ENSDARG00000045156 rgs9b / regulator of G protein signaling 9b / RGS9* / O54828* / O75916* / regulator of G protein signaling 9*  / complex / reaction
 ENSDARG00000086756 RGS9BP / si:ch73-167i17.6 / Q6ZS82* / regulator of G protein signaling 9 binding protein*  / complex






 

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