ENSGALG00000039307


Gallus gallus

Features
Gene ID: ENSGALG00000039307
  
Biological name :GNB5
  
Synonyms : GNB5 / G protein subunit beta 5
  
Possible biological names infered from orthology : guanine nucleotide binding protein (G protein), beta 5 / O14775 / P62881
  
Species: Gallus gallus
  
Chr. number: 10
Strand: 1
Band:
Gene start: 8866333
Gene end: 8887402
  
Corresponding Affymetrix probe sets: Gga.5724.1.S1_at (Chicken Array)   GgaAffx.2902.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000048497
NCBI entrez gene - 415417     See in Manteia.
RefSeq - NM_001293242
RefSeq - XM_015291904
RefSeq Peptide - NP_001280171
swissprot - A0A1D5P714
Ensembl - ENSGALG00000039307
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gnb5aENSDARG00000099685Danio rerio
 gnb5bENSDARG00000055377Danio rerio
 GNB5ENSG00000069966Homo sapiens
 Gnb5ENSMUSG00000032192Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GNB4 / G protein subunit beta 4 / P29387* / Q9HAV0* / guanine nucleotide binding protein (G protein), beta 4*ENSGALG0000000898351
GNB1 / G protein subunit beta 1 / P62873* / P62874* / guanine nucleotide binding protein (G protein), beta 1*ENSGALG0000000133449
GNB3 / G protein subunit beta 3 / P16520* / Q61011* / guanine nucleotide binding protein (G protein), beta 3*ENSGALG0000003443849
WDR47 / WD repeat domain 47 / O94967* / Q8CGF6*ENSGALG0000000212929


Protein motifs (from Interpro)
Interpro ID Name
 IPR001632  G-protein, beta subunit
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR016346  Guanine nucleotide-binding protein, beta subunit
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007212 dopamine receptor signaling pathway IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:1901386 negative regulation of voltage-gated calcium channel activity IEA
 cellular_componentGO:0001750 photoreceptor outer segment IEA
 cellular_componentGO:0001917 photoreceptor inner segment IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0043209 myelin sheath IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0031682 G-protein gamma-subunit binding IEA
 molecular_functionGO:0051087 chaperone binding IEA


Pathways (from Reactome)
Pathway description
G-protein activation
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Thromboxane signalling through TP receptor
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001275 PDCL / phosducin like / Q13371* / Q9DBX2* / Phosducin-like protein *  / reaction / complex
 ENSGALG00000039772 RGS7 / regulator of G protein signaling 7 / O54829* / P49802*  / complex / reaction






 

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