ENSGALG00000001334


Gallus gallus

Features
Gene ID: ENSGALG00000001334
  
Biological name :GNB1
  
Synonyms : GNB1 / G protein subunit beta 1
  
Possible biological names infered from orthology : guanine nucleotide binding protein (G protein), beta 1 / P62873 / P62874
  
Species: Gallus gallus
  
Chr. number: 21
Strand: 1
Band:
Gene start: 1923159
Gene end: 1956964
  
Corresponding Affymetrix probe sets: Gga.8857.1.S1_s_at (Chicken Array)   GgaAffx.11922.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000058045
Ensembl peptide - ENSGALP00000059793
Ensembl peptide - ENSGALP00000002038
Ensembl peptide - ENSGALP00000039575
NCBI entrez gene - 419402     See in Manteia.
RefSeq - XM_015296859
RefSeq - NM_001012835
RefSeq - XM_015296856
RefSeq - XM_015296857
RefSeq - XM_015296858
RefSeq Peptide - NP_001012853
swissprot - A0A1L1RM11
swissprot - F1NLV4
swissprot - A0A1D5PYJ0
Ensembl - ENSGALG00000001334
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gnb1aENSDARG00000090454Danio rerio
 gnb1bENSDARG00000104372Danio rerio
 GNB1ENSG00000078369Homo sapiens
 Gnb1ENSMUSG00000029064Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GNB4 / G protein subunit beta 4 / P29387* / Q9HAV0* / guanine nucleotide binding protein (G protein), beta 4*ENSGALG0000000898376
GNB3 / G protein subunit beta 3 / P16520* / Q61011* / guanine nucleotide binding protein (G protein), beta 3*ENSGALG0000003443869
GNB5 / G protein subunit beta 5 / O14775* / P62881* / guanine nucleotide binding protein (G protein), beta 5*ENSGALG0000003930743
WDR47 / WD repeat domain 47 / O94967* / Q8CGF6*ENSGALG0000000212922


Protein motifs (from Interpro)
Interpro ID Name
 IPR001632  G-protein, beta subunit
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR016346  Guanine nucleotide-binding protein, beta subunit
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0050909 sensory perception of taste IEA
 biological_processGO:0060041 retina development in camera-type eye IEA
 cellular_componentGO:0001750 photoreceptor outer segment IEA
 cellular_componentGO:0005834 heterotrimeric G-protein complex IEA
 cellular_componentGO:0043209 myelin sheath IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0051020 GTPase binding IEA


Pathways (from Reactome)
Pathway description
Activation of G protein gated Potassium channels
G-protein activation
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Thromboxane signalling through TP receptor
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001181 KCNJ5 / potassium voltage-gated channel subfamily J member 5 / P48544* / P48545* / G protein-activated inward rectifier potassium channel 4 *  / complex
 ENSGALG00000001275 PDCL / phosducin like / Q13371* / Q9DBX2* / Phosducin-like protein *  / reaction / complex
 ENSGALG00000036028 GNA13 / G protein subunit alpha 13 / P27601* / Q14344* / guanine nucleotide binding protein, alpha 13*  / complex / reaction
 ENSGALG00000001334 GNB1 / G protein subunit beta 1 / P62873* / P62874* / guanine nucleotide binding protein (G protein), beta 1*  / reaction
 ENSGALG00000038787 ADRA1D* / P25100* / adrenoceptor alpha 1D*  / reaction / complex
 ENSGALG00000006719 GNAZ / G protein subunit alpha z / O70443* / P19086* / guanine nucleotide binding protein, alpha z subunit*  / complex / reaction
 ENSGALG00000023379 F2RL2 / coagulation factor II thrombin receptor like 2 / O00254* / O08675* / Proteinase-activated receptor 3 *  / complex / reaction
 ENSGALG00000010357 P2RY1 / P34996 / P2Y purinoceptor 1 / P47900* / P49650* / purinergic receptor P2Y1* / purinergic receptor P2Y, G-protein coupled 1*  / complex
 ENSGALG00000038084 GNAT2 / G protein subunit alpha transducin 2 / P19087* / P50149* / guanine nucleotide binding protein, alpha transducing 2*  / complex
 ENSGALG00000003163 GNAO1 / G protein subunit alpha o1 / P09471* / P18872* / guanine nucleotide binding protein, alpha O*  / complex
 ENSGALG00000001416 ADRA1B / adrenoceptor alpha 1B / P35368*  / complex / reaction
 ENSGALG00000000469 ADRA1A / adrenoceptor alpha 1A / P35348* / P97718* / Alpha-1A adrenergic receptor *  / complex / reaction
 ENSGALG00000002098 GRIK3 / glutamate ionotropic receptor kainate type subunit 3 / B1AS29* / Q13003* / Glutamate receptor ionotropic, kainate 3 *  / reaction / complex
 ENSGALG00000004373 KCNJ16 / potassium voltage-gated channel subfamily J member 16 / Q9NPI9* / Q9Z307* / Inward rectifier potassium channel 16 *  / complex
 ENSGALG00000004721 F1NHE9 / ATP-sensitive inward rectifier potassium channel 12 / KCNJ18* / P52187* / Q14500* / B7U540* / KCNJ12* / potassium voltage-gated channel subfamily J member 18* / potassium voltage-...  / complex
 ENSGALG00000008382 GNAI1 / guanine nucleotide-binding protein G(i) subunit alpha-1 / P63096* / B2RSH2* / G protein subunit alpha i1* / guanine nucleotide binding protein (G protein), alpha inhibiting 1*  / reaction / complex
 ENSGALG00000008875 PLCB1 / phospholipase C beta 1 / Q9NQ66* / Q9Z1B3* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 *  / complex / reaction
 ENSGALG00000008081 PIK3CG / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma / P48736* / Q9JHG7* / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform *  / complex / reaction
 ENSGALG00000004924 OPNP / OPN1LW* / OPN1MW* / P0DN78* / O35599* / P04000* / P04001* / P0DN77* / OPN1MW3* / OPN1MW2* / opsin 1, long wave sensitive* / Medium-wave-sensitive opsin 1 * / opsin 1, medium wave sen...  / complex / reaction
 ENSGALG00000008427 GNAT3 / G protein subunit alpha transducin 3 / A8MTJ3* / Q3V3I2* / guanine nucleotide binding protein, alpha transducing 3*  / complex / reaction
 ENSGALG00000013200 GABBR2 / gamma-aminobutyric acid type B receptor subunit 2 / O75899* / Q80T41*  / complex
 ENSGALG00000015608 ADRA2C / adrenoceptor alpha 2C / P18825* / Q01337* / Alpha-2C adrenergic receptor *  / reaction / complex
 ENSGALG00000016600 POMC / pro-opiomelanocortin precursor / P01193* / P01189* / proopiomelanocortin* / pro-opiomelanocortin-alpha*  / reaction / complex
 ENSGALG00000015177 GNAQ / G protein subunit alpha q / P21279* / P50148* / guanine nucleotide binding protein, alpha q polypeptide*  / reaction / complex
 ENSGALG00000016055 KCNJ15 / potassium voltage-gated channel subfamily J member 15 / O88932* / Q99712* / ATP-sensitive inward rectifier potassium channel 15 *  / complex
 ENSGALG00000015176 GNA14 / G protein subunit alpha 14 / O95837* / P30677* / guanine nucleotide binding protein, alpha 14*  / reaction / complex
 ENSGALG00000027211 PDYN / prodynorphin / P01213*  / complex / reaction
 ENSGALG00000027629 GNG2 / G protein subunit gamma 2 / P59768* / P63213* / guanine nucleotide binding protein (G protein), gamma 2*  / complex / reaction
 ENSGALG00000028697 GNAT1 / G protein subunit alpha transducin 1 / P11488* / P20612* / guanine nucleotide binding protein, alpha transducing 1*  / complex
 ENSGALG00000042351 PIK3R6 / phosphoinositide-3-kinase regulatory subunit 6 / Q3U6Q4* / Q5UE93*  / reaction / complex
 ENSGALG00000042105 PLCB2 / phospholipase C beta 2 / A3KGF7* / Q00722* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 *  / reaction / complex






 

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