Manteia

ENSGALG00000015177

Gallus gallus

Features

Gene ID:	ENSGALG00000015177

Biological name :	GNAQ

Synonyms :	GNAQ / G protein subunit alpha q

Possible biological names infered from orthology :	guanine nucleotide binding protein, alpha q polypeptide / P21279 / P50148

Species:	Gallus gallus

Chr. number:	Z
Strand:	-1
Band:
Gene start:	37785034
Gene end:	37901983

Corresponding Affymetrix probe sets:	Gga.17028.1.S1_at (Chicken Array) GgaAffx.9661.1.S1_at (Chicken Array) GgaAffx.9662.1.S1_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000024446 NCBI entrez gene - 427262 See in Manteia. RefSeq - NM_001031427 RefSeq Peptide - NP_001026598 swissprot - Q5F3B5 Ensembl - ENSGALG00000015177

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
gnaq	ENSDARG00000011487	Danio rerio
GNAQ	ENSG00000156052	Homo sapiens
Gnaq	ENSMUSG00000024639	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
GNA11	ENSGALG00000003238	91
GNA14 / G protein subunit alpha 14 / O95837* / P30677* / guanine nucleotide binding protein, alpha 14*	ENSGALG00000015176	77
GNAI1 / guanine nucleotide-binding protein G(i) subunit alpha-1 / P63096* / B2RSH2* / G protein subunit alpha i1* / guanine nucleotide binding protein (G protein), alpha inhibiting 1*	ENSGALG00000008382	51
GNAI3 / guanine nucleotide-binding protein G(k) subunit alpha / P08754* / Q9DC51* / G protein subunit alpha i3* / guanine nucleotide binding protein (G protein), alpha inhibiting 3*	ENSGALG00000041700	51
GNAT2 / G protein subunit alpha transducin 2 / P19087* / P50149* / guanine nucleotide binding protein, alpha transducing 2*	ENSGALG00000038084	50
GNAT1 / G protein subunit alpha transducin 1 / P11488* / P20612* / guanine nucleotide binding protein, alpha transducing 1*	ENSGALG00000028697	50
GNAI2 / G protein subunit alpha i2 / P04899* / P08752* / guanine nucleotide binding protein (G protein), alpha inhibiting 2*	ENSGALG00000035645	50
GNAO1 / G protein subunit alpha o1 / P09471* / P18872* / guanine nucleotide binding protein, alpha O*	ENSGALG00000003163	49
GNAT3 / G protein subunit alpha transducin 3 / A8MTJ3* / Q3V3I2* / guanine nucleotide binding protein, alpha transducing 3*	ENSGALG00000008427	48
GNAZ / G protein subunit alpha z / O70443* / P19086* / guanine nucleotide binding protein, alpha z subunit*	ENSGALG00000006719	48
GNA13 / G protein subunit alpha 13 / P27601* / Q14344* / guanine nucleotide binding protein, alpha 13*	ENSGALG00000036028	47
GNA12 / G protein subunit alpha 12 / P27600* / Q03113* / guanine nucleotide binding protein, alpha 12*	ENSGALG00000004368	28

Protein motifs (from Interpro)

Interpro ID	Name
IPR000654	G-protein alpha subunit, group Q
IPR001019	Guanine nucleotide binding protein (G-protein), alpha subunit
IPR011025	G protein alpha subunit, helical insertion
IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0001501	skeletal system development	IEA
biological_process	GO:0001508	action potential	IEA
biological_process	GO:0006469	negative regulation of protein kinase activity	IEA
biological_process	GO:0007165	signal transduction	IEA
biological_process	GO:0007186	G-protein coupled receptor signaling pathway	IEA
biological_process	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway	IEA
biological_process	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway	IMP
biological_process	GO:0007215	glutamate receptor signaling pathway	IEA
biological_process	GO:0007507	heart development	IEA
biological_process	GO:0007603	phototransduction, visible light	IMP
biological_process	GO:0009649	entrainment of circadian clock	IMP
biological_process	GO:0009791	post-embryonic development	IEA
biological_process	GO:0016322	neuron remodeling	IEA
biological_process	GO:0021884	forebrain neuron development	IEA
biological_process	GO:0042711	maternal behavior	IEA
biological_process	GO:0042733	embryonic digit morphogenesis	IEA
biological_process	GO:0043547	positive regulation of GTPase activity	IEA
biological_process	GO:0045634	regulation of melanocyte differentiation	IEA
biological_process	GO:0048066	developmental pigmentation	IEA
biological_process	GO:0050821	protein stabilization	IEA
biological_process	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway	IEA
cellular_component	GO:0001750	photoreceptor outer segment	IDA
cellular_component	GO:0005834	heterotrimeric G-protein complex	IBA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0030425	dendrite	IEA
cellular_component	GO:0044297	cell body	IEA
cellular_component	GO:0097232	lamellar body membrane	IDA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0001664	G-protein coupled receptor binding	IEA
molecular_function	GO:0002046	opsin binding	IPI
molecular_function	GO:0003924	GTPase activity	IBA
molecular_function	GO:0004871	obsolete signal transducer activity	IBA
molecular_function	GO:0005096	GTPase activator activity	IEA
molecular_function	GO:0005525	GTP binding	IEA
molecular_function	GO:0019001	guanyl nucleotide binding	IEA
molecular_function	GO:0031683	G-protein beta/gamma-subunit complex binding	IBA
molecular_function	GO:0031826	type 2A serotonin receptor binding	IBA

Pathways (from Reactome)

Pathway description

G alpha (q) signalling events

ADP signalling through P2Y purinoceptor 1

Thromboxane signalling through TP receptor

Thrombin signalling through proteinase activated receptors (PARs)

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSGALG00000008875	PLCB1 / phospholipase C beta 1 / Q9NQ66* / Q9Z1B3* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 *	/ reaction / complex
ENSGALG00000027629	GNG2 / G protein subunit gamma 2 / P59768* / P63213* / guanine nucleotide binding protein (G protein), gamma 2*	/ reaction / complex
ENSGALG00000008907	PLCB4 / phospholipase C beta 4 / Q15147*	/ complex / reaction
ENSGALG00000001334	GNB1 / G protein subunit beta 1 / P62873* / P62874* / guanine nucleotide binding protein (G protein), beta 1*	/ reaction / complex
ENSGALG00000008934	PIK3CA / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha / P42336* / P42337* / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform *	/ complex / reaction
ENSGALG00000010357	P2RY1 / P34996 / P2Y purinoceptor 1 / P47900* / P49650* / purinergic receptor P2Y1* / purinergic receptor P2Y, G-protein coupled 1*	/ complex
ENSGALG00000042105	PLCB2 / phospholipase C beta 2 / A3KGF7* / Q00722* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 *	/ complex / reaction
ENSGALG00000014786	PIK3R1 / phosphoinositide-3-kinase regulatory subunit 1 / P26450* / P27986*	/ reaction / complex
ENSGALG00000023379	F2RL2 / coagulation factor II thrombin receptor like 2 / O00254* / O08675* / Proteinase-activated receptor 3 *	/ complex / reaction
ENSGALG00000031495	TRIO / trio Rho guanine nucleotide exchange factor / O75962* / Q0KL02* / Triple functional domain protein *	/ reaction / complex

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr