Manteia

ENSGALG00000036028

Gallus gallus

Features

Gene ID:	ENSGALG00000036028

Biological name :	GNA13

Synonyms :	GNA13 / G protein subunit alpha 13

Possible biological names infered from orthology :	guanine nucleotide binding protein, alpha 13 / P27601 / Q14344

Species:	Gallus gallus

Chr. number:	18
Strand:	1
Band:
Gene start:	7826567
Gene end:	7849764

Corresponding Affymetrix probe sets:	Gga.10622.1.S1_at (Chicken Array) Gga.16821.1.S1_at (Chicken Array) Gga.17577.1.S1_at (Chicken Array) GgaAffx.20958.1.S1_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000055111 NCBI entrez gene - 417434 See in Manteia. RefSeq - XM_415686 swissprot - A0A1D5PQE8 Ensembl - ENSGALG00000036028

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
gna13a	ENSDARG00000073765	Danio rerio
gna13b	ENSDARG00000037924	Danio rerio
GNA13	ENSG00000120063	Homo sapiens
Gna13	ENSMUSG00000020611	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
GNA11	ENSGALG00000003238	45
GNA14 / G protein subunit alpha 14 / O95837* / P30677* / guanine nucleotide binding protein, alpha 14*	ENSGALG00000015176	44
GNAQ / G protein subunit alpha q / P21279* / P50148* / guanine nucleotide binding protein, alpha q polypeptide*	ENSGALG00000015177	44
GNA12 / G protein subunit alpha 12 / P27600* / Q03113* / guanine nucleotide binding protein, alpha 12*	ENSGALG00000004368	42
GNAO1 / G protein subunit alpha o1 / P09471* / P18872* / guanine nucleotide binding protein, alpha O*	ENSGALG00000003163	39
GNAT3 / G protein subunit alpha transducin 3 / A8MTJ3* / Q3V3I2* / guanine nucleotide binding protein, alpha transducing 3*	ENSGALG00000008427	38
GNAI1 / guanine nucleotide-binding protein G(i) subunit alpha-1 / P63096* / B2RSH2* / G protein subunit alpha i1* / guanine nucleotide binding protein (G protein), alpha inhibiting 1*	ENSGALG00000008382	37
GNAT1 / G protein subunit alpha transducin 1 / P11488* / P20612* / guanine nucleotide binding protein, alpha transducing 1*	ENSGALG00000028697	37
GNAI2 / G protein subunit alpha i2 / P04899* / P08752* / guanine nucleotide binding protein (G protein), alpha inhibiting 2*	ENSGALG00000035645	37
GNAI3 / guanine nucleotide-binding protein G(k) subunit alpha / P08754* / Q9DC51* / G protein subunit alpha i3* / guanine nucleotide binding protein (G protein), alpha inhibiting 3*	ENSGALG00000041700	37
GNAT2 / G protein subunit alpha transducin 2 / P19087* / P50149* / guanine nucleotide binding protein, alpha transducing 2*	ENSGALG00000038084	37
GNAZ / G protein subunit alpha z / O70443* / P19086* / guanine nucleotide binding protein, alpha z subunit*	ENSGALG00000006719	36

Protein motifs (from Interpro)

Interpro ID	Name
IPR000469	G-protein alpha subunit, group 12/13
IPR001019	Guanine nucleotide binding protein (G-protein), alpha subunit
IPR011025	G protein alpha subunit, helical insertion
IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0001525	angiogenesis	IEA
biological_process	GO:0001569	branching involved in blood vessel morphogenesis	IEA
biological_process	GO:0001701	in utero embryonic development	IEA
biological_process	GO:0007165	signal transduction	IEA
biological_process	GO:0007186	G-protein coupled receptor signaling pathway	IEA
biological_process	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway	IEA
biological_process	GO:0007264	small GTPase mediated signal transduction	IEA
biological_process	GO:0007266	Rho protein signal transduction	IEA
biological_process	GO:0008360	regulation of cell shape	IEA
biological_process	GO:0030154	cell differentiation	IEA
biological_process	GO:0030168	platelet activation	IEA
biological_process	GO:0030334	regulation of cell migration	IEA
biological_process	GO:0035556	intracellular signal transduction	IEA
cellular_component	GO:0005622	intracellular	IEA
cellular_component	GO:0005829	cytosol	IEA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0001664	G-protein coupled receptor binding	IEA
molecular_function	GO:0003924	GTPase activity	IEA
molecular_function	GO:0004871	obsolete signal transducer activity	IEA
molecular_function	GO:0005525	GTP binding	IEA
molecular_function	GO:0019001	guanyl nucleotide binding	IEA
molecular_function	GO:0031683	G-protein beta/gamma-subunit complex binding	IEA

Pathways (from Reactome)

Pathway description

G alpha (12/13) signalling events

Thromboxane signalling through TP receptor

Thrombin signalling through proteinase activated receptors (PARs)

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSGALG00000001334	GNB1 / G protein subunit beta 1 / P62873* / P62874* / guanine nucleotide binding protein (G protein), beta 1*	/ complex / reaction
ENSGALG00000006663	ARHGEF12 / Rho guanine nucleotide exchange factor 12 / Q8R4H2* / Q9NZN5* / Mus musculus Rho guanine nucleotide exchange factor (GEF) 12 (Arhgef12), transcript variant 2, mRNA.*	/ complex / reaction
ENSGALG00000027629	GNG2 / G protein subunit gamma 2 / P59768* / P63213* / guanine nucleotide binding protein (G protein), gamma 2*	/ complex / reaction
ENSGALG00000023379	F2RL2 / coagulation factor II thrombin receptor like 2 / O00254* / O08675* / Proteinase-activated receptor 3 *	/ reaction / complex
ENSGALG00000006526	PLXNB1 / plexin B1 / O43157* / Q8CJH3*	/ reaction / complex
ENSGALG00000000469	ADRA1A / adrenoceptor alpha 1A / P35348* / P97718* / Alpha-1A adrenergic receptor *	/ reaction / complex
ENSGALG00000001416	ADRA1B / adrenoceptor alpha 1B / P35368*	/ complex / reaction
ENSGALG00000038787	ADRA1D* / P25100* / adrenoceptor alpha 1D*	/ complex / reaction

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr