ENSGALG00000023379


Gallus gallus

Features
Gene ID: ENSGALG00000023379
  
Biological name :F2RL2
  
Synonyms : coagulation factor II thrombin receptor like 2 / F2RL2
  
Possible biological names infered from orthology : O00254 / O08675 / Proteinase-activated receptor 3
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 23491744
Gene end: 23494829
  
Corresponding Affymetrix probe sets: Gga.11368.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000037768
NCBI entrez gene - 768449     See in Manteia.
RefSeq - XM_001231245
swissprot - F1P2V3
Ensembl - ENSGALG00000023379
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01071020.1ENSDARG00000079472Danio rerio
 f2rl2ENSDARG00000090524Danio rerio
 F2RL2ENSG00000164220Homo sapiens
 F2rl2ENSMUSG00000021675Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
F2RL3 / F2R like thrombin or trypsin receptor 3 / O88634* / Q96RI0* / Proteinase-activated receptor 4 *ENSGALG0000004448532
F2RL1 / F2R like trypsin receptor 1 / P55085* / P55086* / Proteinase-activated receptor 2 *ENSGALG0000001498432
ENSGALG0000000257029
P2RY8 / Q5ZI82 / P2Y purinoceptor 8 / Q86VZ1* / P2Y receptor family member 8*ENSGALG0000001668728
F2R / coagulation factor II thrombin receptor / P25116* / P30558* / Proteinase-activated receptor 1 *ENSGALG0000001498323
GPR132 / G protein-coupled receptor 132 / Q9UNW8* / Q9Z282*ENSGALG0000002740722
GPR65 / G protein-coupled receptor 65 / Q8IYL9*ENSGALG0000001059520
GPR68 / G protein-coupled receptor 68 / Q15743* / Q8BFQ3* / Ovarian cancer G-protein coupled receptor 1 *ENSGALG0000001070720


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR003912  Protease-activated receptor
 IPR003943  Protease-activated receptor 3
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007596 blood coagulation IEA
 biological_processGO:0035025 positive regulation of Rho protein signal transduction IBA
 biological_processGO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway IBA
 biological_processGO:0070493 thrombin-activated receptor signaling pathway IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IBA
 molecular_functionGO:0015057 thrombin-activated receptor activity IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events
Thrombin signalling through proteinase activated receptors (PARs)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001334 GNB1 / G protein subunit beta 1 / P62873* / P62874* / guanine nucleotide binding protein (G protein), beta 1*  / complex / reaction
 ENSGALG00000008332 F2 / prothrombin precursor / P00734* / P19221* / coagulation factor II, thrombin* / Prothrombin Activation peptide fragment 1 Activation peptide fragment 2 Thrombin light chain Thrombin heavy chain*  / complex / reaction
 ENSGALG00000027629 GNG2 / G protein subunit gamma 2 / P59768* / P63213* / guanine nucleotide binding protein (G protein), gamma 2*  / complex / reaction
 ENSGALG00000023379 F2RL2 / coagulation factor II thrombin receptor like 2 / O00254* / O08675* / Proteinase-activated receptor 3 *  / reaction
 ENSGALG00000036028 GNA13 / G protein subunit alpha 13 / P27601* / Q14344* / guanine nucleotide binding protein, alpha 13*  / complex / reaction
 ENSGALG00000015176 GNA14 / G protein subunit alpha 14 / O95837* / P30677* / guanine nucleotide binding protein, alpha 14*  / complex / reaction
 ENSGALG00000015177 GNAQ / G protein subunit alpha q / P21279* / P50148* / guanine nucleotide binding protein, alpha q polypeptide*  / reaction / complex






 

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