ENSDARG00000090524


Danio rerio

Features
Gene ID: ENSDARG00000090524
  
Biological name :f2rl2
  
Synonyms : coagulation factor II (thrombin) receptor-like 2 / f2rl2
  
Possible biological names infered from orthology : O00254 / O08675 / Proteinase-activated receptor 3
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 46146084
Gene end: 46152740
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000108581
NCBI entrez gene - 100148468     See in Manteia.
swissprot - F1QQR2
ZFIN ID - ZDB-GENE-110127-4
Ensembl - ENSDARG00000090524
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 F2RL2ENSGALG00000023379Gallus gallus
 F2RL2ENSG00000164220Homo sapiens
 F2rl2ENSMUSG00000021675Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CABZ01071020.1 / F2RL2* / O00254* / coagulation factor II thrombin receptor like 2*ENSDARG0000007947241
si:dkey-163m14.6ENSDARG0000009004128
si:dkey-163m14.4ENSDARG0000008746927
si:dkey-163m14.2ENSDARG0000005950727
f2rl1.1 / coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1 / F2RL1* / P55086* / P55085* / F2R like trypsin receptor 1* / Proteinase-activated receptor 2 *ENSDARG0000006885626
zgc:171965ENSDARG0000007763826
si:dkey-163m14.7ENSDARG0000008623626
si:dkey-163m14.10ENSDARG0000008626225
F2RL3 / si:ch211-132p1.2 / O88634* / Q96RI0* / Proteinase-activated receptor 4 * / F2R like thrombin or trypsin receptor 3*ENSDARG0000007939925
f2r / coagulation factor II (thrombin) receptor / P25116* / P30558* / Proteinase-activated receptor 1 *ENSDARG0000006001225
f2rl1.2 / coagulation factor II (thrombin) receptor-like 1, tandem duplicate 2 / F2RL1* / P55086* / P55085* / F2R like trypsin receptor 1* / Proteinase-activated receptor 2 *ENSDARG0000007754023
p2ry8 / P2Y receptor family member 8 / Q86VZ1*ENSDARG0000005556022
gpr65 / G protein-coupled receptor 65 / Q8IYL9*ENSDARG0000004595721
gpr4 / G protein-coupled receptor 4 / P46093* / Q8BUD0*ENSDARG0000007947921
gpr184 / G protein-coupled receptor 184ENSDARG0000010291220
GPR68 / G protein-coupled receptor 68 / Q15743*ENSDARG0000005371120
si:ch211-231m23.4 / FFAR3* / GPR42* / FFAR2* / Q8VCK6* / O15529* / O15552* / Q3UFD7* / O14843* / free fatty acid receptor 2* / free fatty acid receptor 3* / G protein-coupled receptor 42 (g...ENSDARG0000004129220
gpr132b / G protein-coupled receptor 132b / Q9Z282* / GPR132* / Q9UNW8* / G protein-coupled receptor 132*ENSDARG0000010354020
si:dkey-165a24.9ENSDARG0000009005220
CU855821.1 / GPR42* / FFAR2* / FFAR3* / O15552* / O14843* / O15529* / free fatty acid receptor 2* / free fatty acid receptor 3* / G protein-coupled receptor 42 (gene/pseudogene)*ENSDARG0000007966119


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR003912  Protease-activated receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007596 blood coagulation IEA
 biological_processGO:0070493 thrombin-activated receptor signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0015057 thrombin-activated receptor activity IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events
Thrombin signalling through proteinase activated receptors (PARs)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000011487 gnaq / guanine nucleotide binding protein (G protein), q polypeptide / P50148* / P21279* / G protein subunit alpha q* / guanine nucleotide binding protein, alpha q polypeptide*  / complex / reaction
 ENSDARG00000025826 gna12a / guanine nucleotide binding protein (G protein) alpha 12a / GNA12* / Q03113* / P27600* / G protein subunit alpha 12* / guanine nucleotide binding protein, alpha 12*  / complex / reaction
 ENSDARG00000036041 f2 / coagulation factor II (thrombin) / P00734* / P19221* / Prothrombin Activation peptide fragment 1 Activation peptide fragment 2 Thrombin light chain Thrombin heavy chain*  / reaction / complex
 ENSDARG00000060012 f2r / coagulation factor II (thrombin) receptor / P25116* / P30558* / Proteinase-activated receptor 1 *  / reaction
 ENSDARG00000056831 gng2 / guanine nucleotide binding protein (G protein), gamma 2 / P59768* / P63213* / G protein subunit gamma 2*  / reaction / complex
 ENSDARG00000025013 gna14a / guanine nucleotide binding protein (G protein), alpha 14a / GNA14* / P30677* / O95837* / G protein subunit alpha 14* / guanine nucleotide binding protein, alpha 14*  / reaction / complex
 ENSDARG00000090524 f2rl2 / coagulation factor II (thrombin) receptor-like 2 / O00254*  / reaction
 ENSDARG00000079399 F2RL3 / si:ch211-132p1.2 / O88634* / Q96RI0* / Proteinase-activated receptor 4 * / F2R like thrombin or trypsin receptor 3*  / reaction
 ENSDARG00000104372 gnb1b / guanine nucleotide binding protein (G protein), beta polypeptide 1b / GNB1* / P62874* / P62873* / G protein subunit beta 1* / guanine nucleotide binding protein (G protein), beta 1*  / complex / reaction
 ENSDARG00000079472 CABZ01071020.1 / F2RL2* / O00254* / coagulation factor II thrombin receptor like 2*  / reaction
 ENSDARG00000073765 gna13a / guanine nucleotide binding protein (G protein), alpha 13a / GNA13* / Q14344* / P27601* / G protein subunit alpha 13* / guanine nucleotide binding protein, alpha 13*  / reaction / complex
 ENSDARG00000016364 gna15.1 / guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1 / GNA15* / P30679* / P30678* / G protein subunit alpha 15* / guanine nucleotide binding pro...  / reaction / complex
 ENSDARG00000090454 gnb1a / Q6PH57 / guanine nucleotide binding protein (G protein), beta polypeptide 1a / GNB1* / P62873* / G protein subunit beta 1*  / reaction / complex






 

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