ENSDARG00000079399


Danio rerio

Features
Gene ID: ENSDARG00000079399
  
Biological name :F2RL3
  
Synonyms : F2RL3 / si:ch211-132p1.2
  
Possible biological names infered from orthology : F2R like thrombin or trypsin receptor 3 / O88634 / Proteinase-activated receptor 4 / Q96RI0
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 36869273
Gene end: 36878988
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000098661
NCBI entrez gene - 793315     See in Manteia.
swissprot - E7FDD1
ZFIN ID - ZDB-GENE-130530-869
Ensembl - ENSDARG00000079399
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 F2RL3ENSGALG00000044485Gallus gallus
 F2RL3ENSG00000127533Homo sapiens
 F2rl3ENSMUSG00000050147Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
f2rl1.2 / coagulation factor II (thrombin) receptor-like 1, tandem duplicate 2 / F2RL1* / P55086* / P55085* / F2R like trypsin receptor 1* / Proteinase-activated receptor 2 *ENSDARG0000007754032
f2rl1.1 / coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1 / F2RL1* / P55086* / P55085* / F2R like trypsin receptor 1* / Proteinase-activated receptor 2 *ENSDARG0000006885631
p2ry8 / P2Y receptor family member 8 / Q86VZ1*ENSDARG0000005556028
f2r / coagulation factor II (thrombin) receptor / P25116* / P30558* / Proteinase-activated receptor 1 *ENSDARG0000006001228
CABZ01071020.1 / F2RL2* / O00254* / coagulation factor II thrombin receptor like 2*ENSDARG0000007947227
si:dkey-163m14.6ENSDARG0000009004125
si:dkey-163m14.4ENSDARG0000008746925
f2rl2 / coagulation factor II (thrombin) receptor-like 2 / O00254*ENSDARG0000009052425
si:dkey-163m14.7ENSDARG0000008623625
si:dkey-163m14.2ENSDARG0000005950724
zgc:171965ENSDARG0000007763823
si:dkey-163m14.10ENSDARG0000008626222
gpr4 / G protein-coupled receptor 4 / P46093* / Q8BUD0*ENSDARG0000007947921
si:ch73-90p23.1 / FFAR3* / GPR42* / FFAR2* / Q8VCK6* / O15529* / O15552* / Q3UFD7* / O14843* / free fatty acid receptor 2* / free fatty acid receptor 3* / G protein-coupled receptor 42 (gen...ENSDARG0000009790121
si:ch211-231m23.4 / FFAR3* / GPR42* / FFAR2* / Q8VCK6* / O15529* / O15552* / Q3UFD7* / O14843* / free fatty acid receptor 2* / free fatty acid receptor 3* / G protein-coupled receptor 42 (g...ENSDARG0000004129221
CU855821.1 / GPR42* / FFAR2* / FFAR3* / O15552* / O14843* / O15529* / free fatty acid receptor 2* / free fatty acid receptor 3* / G protein-coupled receptor 42 (gene/pseudogene)*ENSDARG0000007966120
gpr132b / G protein-coupled receptor 132b / Q9Z282* / GPR132* / Q9UNW8* / G protein-coupled receptor 132*ENSDARG0000010354020
si:dkey-165a24.9ENSDARG0000009005220
GPR68 / G protein-coupled receptor 68 / Q15743*ENSDARG0000005371120
si:dkey-211g8.6 / FFAR3* / GPR42* / FFAR2* / Q8VCK6* / O15529* / O15552* / Q3UFD7* / O14843* / free fatty acid receptor 2* / free fatty acid receptor 3* / G protein-coupled receptor 42 (gen...ENSDARG0000006308820


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0035025 positive regulation of Rho protein signal transduction IBA
 biological_processGO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway IBA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IBA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events
Thrombin signalling through proteinase activated receptors (PARs)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000011487 gnaq / guanine nucleotide binding protein (G protein), q polypeptide / P50148* / P21279* / G protein subunit alpha q* / guanine nucleotide binding protein, alpha q polypeptide*  / complex / reaction
 ENSDARG00000025826 gna12a / guanine nucleotide binding protein (G protein) alpha 12a / GNA12* / Q03113* / P27600* / G protein subunit alpha 12* / guanine nucleotide binding protein, alpha 12*  / complex / reaction
 ENSDARG00000036041 f2 / coagulation factor II (thrombin) / P00734* / P19221* / Prothrombin Activation peptide fragment 1 Activation peptide fragment 2 Thrombin light chain Thrombin heavy chain*  / reaction / complex
 ENSDARG00000060012 f2r / coagulation factor II (thrombin) receptor / P25116* / P30558* / Proteinase-activated receptor 1 *  / reaction
 ENSDARG00000056831 gng2 / guanine nucleotide binding protein (G protein), gamma 2 / P59768* / P63213* / G protein subunit gamma 2*  / reaction / complex
 ENSDARG00000090524 f2rl2 / coagulation factor II (thrombin) receptor-like 2 / O00254*  / reaction
 ENSDARG00000073765 gna13a / guanine nucleotide binding protein (G protein), alpha 13a / GNA13* / Q14344* / P27601* / G protein subunit alpha 13* / guanine nucleotide binding protein, alpha 13*  / complex / reaction
 ENSDARG00000079472 CABZ01071020.1 / F2RL2* / O00254* / coagulation factor II thrombin receptor like 2*  / reaction
 ENSDARG00000104372 gnb1b / guanine nucleotide binding protein (G protein), beta polypeptide 1b / GNB1* / P62874* / P62873* / G protein subunit beta 1* / guanine nucleotide binding protein (G protein), beta 1*  / complex / reaction
 ENSDARG00000016364 gna15.1 / guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1 / GNA15* / P30679* / P30678* / G protein subunit alpha 15* / guanine nucleotide binding pro...  / reaction / complex
 ENSDARG00000090454 gnb1a / Q6PH57 / guanine nucleotide binding protein (G protein), beta polypeptide 1a / GNB1* / P62873* / G protein subunit beta 1*  / reaction / complex
 ENSDARG00000025013 gna14a / guanine nucleotide binding protein (G protein), alpha 14a / GNA14* / P30677* / O95837* / G protein subunit alpha 14* / guanine nucleotide binding protein, alpha 14*  / reaction / complex
 ENSDARG00000079399 F2RL3 / si:ch211-132p1.2 / O88634* / Q96RI0* / Proteinase-activated receptor 4 * / F2R like thrombin or trypsin receptor 3*  / reaction






 

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