ENSGALG00000008382


Gallus gallus

Features
Gene ID: ENSGALG00000008382
  
Biological name :GNAI1
  
Synonyms : GNAI1 / guanine nucleotide-binding protein G(i) subunit alpha-1
  
Possible biological names infered from orthology : B2RSH2 / G protein subunit alpha i1 / guanine nucleotide binding protein (G protein), alpha inhibiting 1 / P63096
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 11370427
Gene end: 11403687
  
Corresponding Affymetrix probe sets: Gga.18910.1.S1_at (Chicken Array)   Gga.18910.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044195
Ensembl peptide - ENSGALP00000013640
NCBI entrez gene - 396368     See in Manteia.
RefSeq - XM_015301090
RefSeq - NM_205403
RefSeq Peptide - NP_990734
swissprot - E1BXS2
Ensembl - ENSGALG00000008382
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gnai3ENSDARG00000030644Danio rerio
 GNAI1ENSG00000127955Homo sapiens
 Gnai1ENSMUSG00000057614Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GNAI3 / guanine nucleotide-binding protein G(k) subunit alpha / P08754* / Q9DC51* / G protein subunit alpha i3* / guanine nucleotide binding protein (G protein), alpha inhibiting 3*ENSGALG0000004170094
GNAI2 / G protein subunit alpha i2 / P04899* / P08752* / guanine nucleotide binding protein (G protein), alpha inhibiting 2*ENSGALG0000003564591
GNAO1 / G protein subunit alpha o1 / P09471* / P18872* / guanine nucleotide binding protein, alpha O*ENSGALG0000000316372
GNAT2 / G protein subunit alpha transducin 2 / P19087* / P50149* / guanine nucleotide binding protein, alpha transducing 2*ENSGALG0000003808470
GNAZ / G protein subunit alpha z / O70443* / P19086* / guanine nucleotide binding protein, alpha z subunit*ENSGALG0000000671968
GNAT1 / G protein subunit alpha transducin 1 / P11488* / P20612* / guanine nucleotide binding protein, alpha transducing 1*ENSGALG0000002869766
GNAT3 / G protein subunit alpha transducin 3 / A8MTJ3* / Q3V3I2* / guanine nucleotide binding protein, alpha transducing 3*ENSGALG0000000842764
GNA11ENSGALG0000000323851
GNAQ / G protein subunit alpha q / P21279* / P50148* / guanine nucleotide binding protein, alpha q polypeptide*ENSGALG0000001517751
GNA14 / G protein subunit alpha 14 / O95837* / P30677* / guanine nucleotide binding protein, alpha 14*ENSGALG0000001517651
GNA13 / G protein subunit alpha 13 / P27601* / Q14344* / guanine nucleotide binding protein, alpha 13*ENSGALG0000003602840
GNA12 / G protein subunit alpha 12 / P27600* / Q03113* / guanine nucleotide binding protein, alpha 12*ENSGALG0000000436828


Protein motifs (from Interpro)
Interpro ID Name
 IPR001019  Guanine nucleotide binding protein (G-protein), alpha subunit
 IPR001408  G-protein alpha subunit, group I
 IPR011025  G protein alpha subunit, helical insertion
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0060236 regulation of mitotic spindle organization IEA
 biological_processGO:1904778 positive regulation of protein localization to cell cortex IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0099738 cell cortex region IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0019001 guanyl nucleotide binding IEA
 molecular_functionGO:0031683 G-protein beta/gamma-subunit complex binding IEA


Pathways (from Reactome)
Pathway description
PLC beta mediated events
Adenylate cyclase inhibitory pathway
G-protein activation
ADP signalling through P2Y purinoceptor 12
G alpha (i) signalling events
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000027629 GNG2 / G protein subunit gamma 2 / P59768* / P63213* / guanine nucleotide binding protein (G protein), gamma 2*  / complex / reaction
 ENSGALG00000001334 GNB1 / G protein subunit beta 1 / P62873* / P62874* / guanine nucleotide binding protein (G protein), beta 1*  / complex / reaction
 ENSGALG00000013785 GNAL / G protein subunit alpha L / P38405* / Q8CGK7* / guanine nucleotide binding protein, alpha stimulating, olfactory type*  / reaction / complex






 

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