Manteia

ENSGALG00000008427

Gallus gallus

Features

Gene ID:	ENSGALG00000008427

Biological name :	GNAT3

Synonyms :	GNAT3 / G protein subunit alpha transducin 3

Possible biological names infered from orthology :	A8MTJ3 / guanine nucleotide binding protein, alpha transducing 3 / Q3V3I2

Species:	Gallus gallus

Chr. number:	1
Strand:	1
Band:
Gene start:	11261662
Gene end:	11291903

Corresponding Affymetrix probe sets:	Gga.17082.1.S1_at (Chicken Array) GgaAffx.11334.1.S1_s_at (Chicken Array) GgaAffx.22578.1.S1_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000013713 NCBI entrez gene - 427851 See in Manteia. RefSeq - NM_001267811 RefSeq Peptide - NP_001254740 swissprot - F1P3R0 Ensembl - ENSGALG00000008427

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
GNAT3	ENSG00000214415	Homo sapiens
Gnat3	ENSMUSG00000028777	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
GNAT2 / G protein subunit alpha transducin 2 / P19087* / P50149* / guanine nucleotide binding protein, alpha transducing 2*	ENSGALG00000038084	76
GNAT1 / G protein subunit alpha transducin 1 / P11488* / P20612* / guanine nucleotide binding protein, alpha transducing 1*	ENSGALG00000028697	76
GNAI1 / guanine nucleotide-binding protein G(i) subunit alpha-1 / P63096* / B2RSH2* / G protein subunit alpha i1* / guanine nucleotide binding protein (G protein), alpha inhibiting 1*	ENSGALG00000008382	64
GNAI3 / guanine nucleotide-binding protein G(k) subunit alpha / P08754* / Q9DC51* / G protein subunit alpha i3* / guanine nucleotide binding protein (G protein), alpha inhibiting 3*	ENSGALG00000041700	63
GNAI2 / G protein subunit alpha i2 / P04899* / P08752* / guanine nucleotide binding protein (G protein), alpha inhibiting 2*	ENSGALG00000035645	63
GNAO1 / G protein subunit alpha o1 / P09471* / P18872* / guanine nucleotide binding protein, alpha O*	ENSGALG00000003163	61
GNAZ / G protein subunit alpha z / O70443* / P19086* / guanine nucleotide binding protein, alpha z subunit*	ENSGALG00000006719	56
GNA14 / G protein subunit alpha 14 / O95837* / P30677* / guanine nucleotide binding protein, alpha 14*	ENSGALG00000015176	49
GNA11	ENSGALG00000003238	49
GNAQ / G protein subunit alpha q / P21279* / P50148* / guanine nucleotide binding protein, alpha q polypeptide*	ENSGALG00000015177	48
GNA13 / G protein subunit alpha 13 / P27601* / Q14344* / guanine nucleotide binding protein, alpha 13*	ENSGALG00000036028	41
GNA12 / G protein subunit alpha 12 / P27600* / Q03113* / guanine nucleotide binding protein, alpha 12*	ENSGALG00000004368	27

Protein motifs (from Interpro)

Interpro ID	Name
IPR001019	Guanine nucleotide binding protein (G-protein), alpha subunit
IPR001408	G-protein alpha subunit, group I
IPR011025	G protein alpha subunit, helical insertion
IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste	IBA
biological_process	GO:0007165	signal transduction	IEA
biological_process	GO:0007186	G-protein coupled receptor signaling pathway	IEA
biological_process	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway	IBA
biological_process	GO:0050909	sensory perception of taste	IEA
biological_process	GO:0050913	sensory perception of bitter taste	IEA
biological_process	GO:0050916	sensory perception of sweet taste	IEA
biological_process	GO:0050917	sensory perception of umami taste	IEA
cellular_component	GO:0001750	photoreceptor outer segment	IBA
cellular_component	GO:0001917	photoreceptor inner segment	IBA
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005834	heterotrimeric G-protein complex	IBA
cellular_component	GO:0032991	protein-containing complex	IEA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0001664	G-protein coupled receptor binding	IBA
molecular_function	GO:0003924	GTPase activity	IBA
molecular_function	GO:0004871	obsolete signal transducer activity	IBA
molecular_function	GO:0005525	GTP binding	IEA
molecular_function	GO:0019001	guanyl nucleotide binding	IEA
molecular_function	GO:0031683	G-protein beta/gamma-subunit complex binding	IBA

Pathways (from Reactome)

Pathway description

PLC beta mediated events

Adenylate cyclase inhibitory pathway

G-protein activation

Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)

ADP signalling through P2Y purinoceptor 12

G alpha (i) signalling events

Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSGALG00000005293	GNG13 / Q9JMF3* / Q9P2W3* / G protein subunit gamma 13* / guanine nucleotide binding protein (G protein), gamma 13*	/ complex
ENSGALG00000013785	GNAL / G protein subunit alpha L / P38405* / Q8CGK7* / guanine nucleotide binding protein, alpha stimulating, olfactory type*	/ complex / reaction
ENSGALG00000001334	GNB1 / G protein subunit beta 1 / P62873* / P62874* / guanine nucleotide binding protein (G protein), beta 1*	/ complex / reaction
ENSGALG00000027629	GNG2 / G protein subunit gamma 2 / P59768* / P63213* / guanine nucleotide binding protein (G protein), gamma 2*	/ reaction / complex

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr