ENSGALG00000000469


Gallus gallus

Features
Gene ID: ENSGALG00000000469
  
Biological name :ADRA1A
  
Synonyms : ADRA1A / adrenoceptor alpha 1A
  
Possible biological names infered from orthology : Alpha-1A adrenergic receptor / P35348 / P97718
  
Species: Gallus gallus
  
Chr. number: 22
Strand: 1
Band:
Gene start: 4528861
Gene end: 4544179
  
Corresponding Affymetrix probe sets: GgaAffx.290.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000000638
NCBI entrez gene - 428203     See in Manteia.
RefSeq - XM_015297497
swissprot - F1NP52
Ensembl - ENSGALG00000000469
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adra1aaENSDARG00000028725Danio rerio
 adra1abENSDARG00000027638Danio rerio
 ADRA1AENSG00000120907Homo sapiens
 Adra1aENSMUSG00000045875Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADRA1B / adrenoceptor alpha 1B / P35368*ENSGALG0000000141651
ADRA1D* / P25100* / adrenoceptor alpha 1D*ENSGALG0000003878749
HTR7 / 5-hydroxytryptamine receptor 7 / P32304* / P34969* / 5-hydroxytryptamine (serotonin) receptor 7*ENSGALG0000004054926
HTR1A / 5-hydroxytryptamine receptor 1A / P08908* / Q64264* / 5-hydroxytryptamine (serotonin) receptor 1A*ENSGALG0000001474225
HTR7LENSGALG0000003508125
HTR1B / 5-hydroxytryptamine receptor 1B / P28222* / P28334* / 5-hydroxytryptamine (serotonin) receptor 1B*ENSGALG0000001589524
ADRA2A / adrenoceptor alpha 2A / P08913*ENSGALG0000002352124
HTR1D / 5-hydroxytryptamine receptor 1D / P28221* / Q61224* / 5-hydroxytryptamine (serotonin) receptor 1D*ENSGALG0000000082024
HTR1F / 5-hydroxytryptamine receptor 1F / P30939* / Q02284* / 5-hydroxytryptamine (serotonin) receptor 1F*ENSGALG0000001549423
HTR1E / 5-hydroxytryptamine receptor 1E / P28566*ENSGALG0000001582623
ADRA2C / adrenoceptor alpha 2C / P18825* / Q01337* / Alpha-2C adrenergic receptor *ENSGALG0000001560823
HTR5A / 5-hydroxytryptamine receptor 5A / P30966* / P47898* / 5-hydroxytryptamine (serotonin) receptor 5A*ENSGALG0000000636222
ENSGALG0000003545721


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001004  Alpha 1A adrenoceptor
 IPR002233  Adrenoceptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001985 negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure IEA
 biological_processGO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure IEA
 biological_processGO:0001996 positive regulation of heart rate by epinephrine-norepinephrine IEA
 biological_processGO:0001997 positive regulation of the force of heart contraction by epinephrine-norepinephrine IEA
 biological_processGO:0006937 regulation of muscle contraction IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IBA
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0007512 adult heart development IEA
 biological_processGO:0010507 negative regulation of autophagy IEA
 biological_processGO:0010613 positive regulation of cardiac muscle hypertrophy IEA
 biological_processGO:0019229 regulation of vasoconstriction IEA
 biological_processGO:0035265 organ growth IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IEA
 biological_processGO:0045907 positive regulation of vasoconstriction IBA
 biological_processGO:0045987 positive regulation of smooth muscle contraction IEA
 biological_processGO:0055117 regulation of cardiac muscle contraction IEA
 biological_processGO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway IBA
 biological_processGO:0097195 pilomotor reflex IEA
 biological_processGO:1903997 positive regulation of non-membrane spanning protein tyrosine kinase activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004935 adrenergic receptor activity IEA
 molecular_functionGO:0004937 alpha1-adrenergic receptor activity IBA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Adrenoceptors
G alpha (q) signalling events
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001334 GNB1 / G protein subunit beta 1 / P62873* / P62874* / guanine nucleotide binding protein (G protein), beta 1*  / reaction / complex
 ENSGALG00000027629 GNG2 / G protein subunit gamma 2 / P59768* / P63213* / guanine nucleotide binding protein (G protein), gamma 2*  / complex / reaction
 ENSGALG00000036028 GNA13 / G protein subunit alpha 13 / P27601* / Q14344* / guanine nucleotide binding protein, alpha 13*  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr