ENSGALG00000023521


Gallus gallus

Features
Gene ID: ENSGALG00000023521
  
Biological name :ADRA2A
  
Synonyms : ADRA2A / adrenoceptor alpha 2A
  
Possible biological names infered from orthology : P08913
  
Species: Gallus gallus
  
Chr. number: 6
Strand: 1
Band:
Gene start: 26252415
Gene end: 26253698
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000038251
NCBI entrez gene - 428980     See in Manteia.
RefSeq - XM_004942276
swissprot - F1NQY7
Ensembl - ENSGALG00000023521
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adra2aENSDARG00000040841Danio rerio
 ADRA2AENSG00000150594Homo sapiens
 Adra2aENSMUSG00000033717Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADRA2C / adrenoceptor alpha 2C / P18825* / Q01337* / Alpha-2C adrenergic receptor *ENSGALG0000001560854
ENSGALG0000003545739
HTR1A / 5-hydroxytryptamine receptor 1A / P08908* / Q64264* / 5-hydroxytryptamine (serotonin) receptor 1A*ENSGALG0000001474230
HTR1B / 5-hydroxytryptamine receptor 1B / P28222* / P28334* / 5-hydroxytryptamine (serotonin) receptor 1B*ENSGALG0000001589529
HTR1D / 5-hydroxytryptamine receptor 1D / P28221* / Q61224* / 5-hydroxytryptamine (serotonin) receptor 1D*ENSGALG0000000082029
HTR1F / 5-hydroxytryptamine receptor 1F / P30939* / Q02284* / 5-hydroxytryptamine (serotonin) receptor 1F*ENSGALG0000001549428
ADRA1B / adrenoceptor alpha 1B / P35368*ENSGALG0000000141628
ADRA1D* / P25100* / adrenoceptor alpha 1D*ENSGALG0000003878727
ADRA1A / adrenoceptor alpha 1A / P35348* / P97718* / Alpha-1A adrenergic receptor *ENSGALG0000000046926
HTR7 / 5-hydroxytryptamine receptor 7 / P32304* / P34969* / 5-hydroxytryptamine (serotonin) receptor 7*ENSGALG0000004054926
HTR7LENSGALG0000003508126
HTR1E / 5-hydroxytryptamine receptor 1E / P28566*ENSGALG0000001582626
HTR5A / 5-hydroxytryptamine receptor 5A / P30966* / P47898* / 5-hydroxytryptamine (serotonin) receptor 5A*ENSGALG0000000636225


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR002233  Adrenoceptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001819 positive regulation of cytokine production IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0032147 activation of protein kinase activity IEA
 biological_processGO:0032148 activation of protein kinase B activity IEA
 biological_processGO:0032870 cellular response to hormone stimulus IEA
 biological_processGO:0035625 obsolete epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0043406 positive regulation of MAP kinase activity IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IEA
 biological_processGO:0045741 positive regulation of epidermal growth factor-activated receptor activity IEA
 biological_processGO:0046676 negative regulation of insulin secretion IEA
 biological_processGO:0050995 negative regulation of lipid catabolic process IEA
 biological_processGO:0051044 positive regulation of membrane protein ectodomain proteolysis IEA
 biological_processGO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus IEA
 biological_processGO:0071875 adrenergic receptor signaling pathway IEA
 biological_processGO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway IBA
 biological_processGO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway IEA
 biological_processGO:0071882 phospholipase C-activating adrenergic receptor signaling pathway IEA
 biological_processGO:0090303 positive regulation of wound healing IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004935 adrenergic receptor activity IBA
 molecular_functionGO:0004938 alpha2-adrenergic receptor activity IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0031696 alpha-2C adrenergic receptor binding IEA
 molecular_functionGO:0031996 thioesterase binding IEA
 molecular_functionGO:0032795 heterotrimeric G-protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0051379 epinephrine binding IEA
 molecular_functionGO:0051380 norepinephrine binding IEA


Pathways (from Reactome)
Pathway description
Adrenoceptors
Adrenaline signalling through Alpha-2 adrenergic receptor
Adrenaline,noradrenaline inhibits insulin secretion
G alpha (i) signalling events
G alpha (z) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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