ENSDARG00000027638


Danio rerio

Features
Gene ID: ENSDARG00000027638
  
Biological name :adra1ab
  
Synonyms : adra1ab / adrenoceptor alpha 1Ab
  
Possible biological names infered from orthology : ADRA1A / adrenoceptor alpha 1A / Alpha-1A adrenergic receptor / P35348 / P97718
  
Species: Danio rerio
  
Chr. number: 10
Strand: -1
Band:
Gene start: 18999841
Gene end: 19011934
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000117062
Ensembl peptide - ENSDARP00000130230
NCBI entrez gene - 557259     See in Manteia.
swissprot - A0A0R4IB14
swissprot - A8DZ94
ZFIN ID - ZDB-GENE-060503-384
Ensembl - ENSDARG00000027638
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ADRA1AENSGALG00000000469Gallus gallus
 ADRA1AENSG00000120907Homo sapiens
 Adra1aENSMUSG00000045875Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
adra1aa / adrenoceptor alpha 1Aa / ADRA1A* / P35348* / adrenoceptor alpha 1A*ENSDARG0000002872558
adra1ba / adrenoceptor alpha 1Ba / ADRA1B* / P35368* / adrenoceptor alpha 1B*ENSDARG0000001131746
adra1bb / adrenoceptor alpha 1Bb / ADRA1B* / P35368* / adrenoceptor alpha 1B*ENSDARG0000004117346
adra1d / adrenoceptor alpha 1D / P25100*ENSDARG0000002410145
htr7a / 5-hydroxytryptamine (serotonin) receptor 7a / HTR7* / P34969* / P32304* / 5-hydroxytryptamine receptor 7* / 5-hydroxytryptamine (serotonin) receptor 7*ENSDARG0000005694928
FO704724.1 / HTR7* / P34969* / 5-hydroxytryptamine receptor 7*ENSDARG0000009985428
htr1aa / 5-hydroxytryptamine (serotonin) receptor 1A a / HTR1A* / Q64264* / P08908* / 5-hydroxytryptamine receptor 1A* / 5-hydroxytryptamine (serotonin) receptor 1A*ENSDARG0000009374527
FP236542.1 / ADRA2B* / P18089* / adrenoceptor alpha 2B*ENSDARG0000011698826
htr7c / 5-hydroxytryptamine (serotonin) receptor 7cENSDARG0000009527226
htr7b / 5-hydroxytryptamine (serotonin) receptor 7bENSDARG0000002758726
adra2c / Q90WY6 / adrenoceptor alpha 2C / P18825* / Q01337* / Alpha-2C adrenergic receptor *ENSDARG0000006966926
htr1fb / 5-hydroxytryptamine (serotonin) receptor 1Fb / HTR1F* / Q02284* / P30939* / 5-hydroxytryptamine receptor 1F* / 5-hydroxytryptamine (serotonin) receptor 1F*ENSDARG0000005358025
adra2da / adrenergic, alpha-2D-, receptor aENSDARG0000009127725
adra2db / adrenergic, alpha-2D-, receptor bENSDARG0000005466725
htr1ab / 5-hydroxytryptamine (serotonin) receptor 1A bENSDARG0000005709825
adra2b / adrenoceptor alpha 2B / P18089*ENSDARG0000010209625
htr5ab / 5-hydroxytryptamine (serotonin) receptor 5A, genome duplicate b / HTR5A* / P47898* / P30966* / 5-hydroxytryptamine receptor 5A* / 5-hydroxytryptamine (serotonin) receptor 5A*ENSDARG0000006855724
htr1b / 5-hydroxytryptamine (serotonin) receptor 1B / P28222* / P28334* / 5-hydroxytryptamine receptor 1B*ENSDARG0000005398724
htr5aa / 5-hydroxytryptamine (serotonin) receptor 5A, genome duplicate a / HTR5A* / P47898* / P30966* / 5-hydroxytryptamine receptor 5A* / 5-hydroxytryptamine (serotonin) receptor 5A*ENSDARG0000003886924
adra2a / adrenoceptor alpha 2A / P08913*ENSDARG0000004084124


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR002233  Adrenoceptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure IBA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IBA
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0045907 positive regulation of vasoconstriction IBA
 biological_processGO:0045987 positive regulation of smooth muscle contraction IBA
 biological_processGO:0071875 adrenergic receptor signaling pathway IEA
 biological_processGO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004935 adrenergic receptor activity IEA
 molecular_functionGO:0004937 alpha1-adrenergic receptor activity IBA


Pathways (from Reactome)
Pathway description
Adrenoceptors
G alpha (q) signalling events
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000025826 gna12a / guanine nucleotide binding protein (G protein) alpha 12a / GNA12* / Q03113* / P27600* / G protein subunit alpha 12* / guanine nucleotide binding protein, alpha 12*  / complex / reaction
 ENSDARG00000056831 gng2 / guanine nucleotide binding protein (G protein), gamma 2 / P59768* / P63213* / G protein subunit gamma 2*  / complex / reaction
 ENSDARG00000073765 gna13a / guanine nucleotide binding protein (G protein), alpha 13a / GNA13* / Q14344* / P27601* / G protein subunit alpha 13* / guanine nucleotide binding protein, alpha 13*  / reaction / complex
 ENSDARG00000090454 gnb1a / Q6PH57 / guanine nucleotide binding protein (G protein), beta polypeptide 1a / GNB1* / P62873* / G protein subunit beta 1*  / complex / reaction
 ENSDARG00000104372 gnb1b / guanine nucleotide binding protein (G protein), beta polypeptide 1b / GNB1* / P62874* / P62873* / G protein subunit beta 1* / guanine nucleotide binding protein (G protein), beta 1*  / complex / reaction






 

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