ENSGALG00000001181


Gallus gallus

Features
Gene ID: ENSGALG00000001181
  
Biological name :KCNJ5
  
Synonyms : KCNJ5 / potassium voltage-gated channel subfamily J member 5
  
Possible biological names infered from orthology : G protein-activated inward rectifier potassium channel 4 / P48544 / P48545
  
Species: Gallus gallus
  
Chr. number: 24
Strand: 1
Band:
Gene start: 1075877
Gene end: 1112534
  
Corresponding Affymetrix probe sets: Gga.546.1.S1_at (Chicken Array)   Gga.546.1.S1_s_at (Chicken Array)   GgaAffx.23423.1.S1_at (Chicken Array)   GgaAffx.23423.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045182
Ensembl peptide - ENSGALP00000001788
NCBI entrez gene - 395925     See in Manteia.
RefSeq - XM_417864
RefSeq - XM_004947965
swissprot - F1P3M0
swissprot - A0A1D5NXT2
Ensembl - ENSGALG00000001181
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnj5ENSDARG00000061014Danio rerio
 KCNJ5ENSG00000120457Homo sapiens
 Kcnj5ENSMUSG00000032034Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNJ6 / potassium voltage-gated channel subfamily J member 6 / P48051* / G protein-activated inward rectifier potassium channel 2 isoform Girk2B *ENSGALG0000001605467
KCNJ3 / G protein-activated inward rectifier potassium channel 1 / P48549* / P63250* / potassium voltage-gated channel subfamily J member 3*ENSGALG0000001253749
ENSGALG0000000993549
ENSGALG0000000692246
F1NHE9 / ATP-sensitive inward rectifier potassium channel 12 / KCNJ18* / P52187* / Q14500* / B7U540* / KCNJ12* / potassium voltage-gated channel subfamily J member 18* / potassium voltage-...ENSGALG0000000472145
KCNJ2 / inward rectifier potassium channel 2 / P35561* / P63252* / potassium voltage-gated channel subfamily J member 2* / potassium inwardly-rectifying channel, subfamily J, member 2*ENSGALG0000000437643
KCNJ4 / potassium voltage-gated channel subfamily J member 4 / P48050*ENSGALG0000001225442
KCNJ11 / potassium voltage-gated channel subfamily J member 11 / Q14654* / Q61743* / ATP-sensitive inward rectifier potassium channel 11 *ENSGALG0000002050538
KCNJ8 / ATP-sensitive inward rectifier potassium channel 8 / P97794* / Q15842* / potassium voltage-gated channel subfamily J member 8* / potassium inwardly-rectifying channel, subfamily J, member 8*ENSGALG0000002637337
KCNJ1 / potassium voltage-gated channel subfamily J member 1 / O88335* / P48048* / ATP-sensitive inward rectifier potassium channel 1 *ENSGALG0000000116733
KCNJ15 / potassium voltage-gated channel subfamily J member 15 / O88932* / Q99712* / ATP-sensitive inward rectifier potassium channel 15 *ENSGALG0000001605529


Protein motifs (from Interpro)
Interpro ID Name
 IPR003277  Potassium channel, inwardly rectifying, Kir3.4
 IPR013518  Potassium channel, inwardly rectifying, Kir, cytoplasmic
 IPR014756  Immunoglobulin E-set
 IPR016449  Potassium channel, inwardly rectifying, Kir


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0010107 potassium ion import IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 biological_processGO:0086091 regulation of heart rate by cardiac conduction IEA
 biological_processGO:0098914 membrane repolarization during atrial cardiac muscle cell action potential IEA
 biological_processGO:1990573 potassium ion import across plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005242 inward rectifier potassium channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0015467 G-protein activated inward rectifier potassium channel activity IEA
 molecular_functionGO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization IEA


Pathways (from Reactome)
Pathway description
Activation of G protein gated Potassium channels
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000013200 GABBR2 / gamma-aminobutyric acid type B receptor subunit 2 / O75899* / Q80T41*  / complex
 ENSGALG00000001181 KCNJ5 / potassium voltage-gated channel subfamily J member 5 / P48544* / P48545* / G protein-activated inward rectifier potassium channel 4 *  / complex
 ENSGALG00000001334 GNB1 / G protein subunit beta 1 / P62873* / P62874* / guanine nucleotide binding protein (G protein), beta 1*  / complex






 

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