ENSGALG00000042351


Gallus gallus

Features
Gene ID: ENSGALG00000042351
  
Biological name :PIK3R6
  
Synonyms : phosphoinositide-3-kinase regulatory subunit 6 / PIK3R6
  
Possible biological names infered from orthology : Q3U6Q4 / Q5UE93
  
Species: Gallus gallus
  
Chr. number: 18
Strand: -1
Band:
Gene start: 1996687
Gene end: 2009739
  
Corresponding Affymetrix probe sets: GgaAffx.23558.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000048229
Ensembl peptide - ENSGALP00000048541
NCBI entrez gene - 769202     See in Manteia.
RefSeq - XM_015295245
RefSeq - XM_004949966
RefSeq - XM_015295244
RefSeq - XM_001232430
RefSeq - XM_004949965
swissprot - A0A1D5P757
swissprot - A0A1D5P6A4
Ensembl - ENSGALG00000042351
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pik3r6bENSDARG00000091140Danio rerio
 PIK3R6ENSG00000276231Homo sapiens
 Pik3r6ENSMUSG00000046207Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PIK3R5 / phosphoinositide 3-kinase regulatory subunit 5 / Q5SW28* / Q8WYR1*ENSGALG0000002616719


Protein motifs (from Interpro)
Interpro ID Name
 IPR019522  Phosphoinositide 3-kinase regulatory subunit 5/6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0042269 regulation of natural killer cell mediated cytotoxicity IEA
 biological_processGO:0043406 positive regulation of MAP kinase activity IEA
 biological_processGO:0043551 regulation of phosphatidylinositol 3-kinase activity IEA
 biological_processGO:0045582 positive regulation of T cell differentiation IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 cellular_componentGO:0005944 phosphatidylinositol 3-kinase complex, class IB IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity IEA
 molecular_functionGO:0046935 1-phosphatidylinositol-3-kinase regulator activity IEA


Pathways (from Reactome)
Pathway description
GPVI-mediated activation cascade
Synthesis of PIPs at the plasma membrane
G beta:gamma signalling through PI3Kgamma


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008081 PIK3CG / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma / P48736* / Q9JHG7* / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform *  / complex
 ENSGALG00000001334 GNB1 / G protein subunit beta 1 / P62873* / P62874* / guanine nucleotide binding protein (G protein), beta 1*  / reaction / complex
 ENSGALG00000027629 GNG2 / G protein subunit gamma 2 / P59768* / P63213* / guanine nucleotide binding protein (G protein), gamma 2*  / complex / reaction






 

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