ENSGALG00000016600


Gallus gallus

Features
Gene ID: ENSGALG00000016600
  
Biological name :POMC
  
Synonyms : POMC / pro-opiomelanocortin precursor
  
Possible biological names infered from orthology : P01189 / P01193 / proopiomelanocortin / pro-opiomelanocortin-alpha
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 105818021
Gene end: 105834013
  
Corresponding Affymetrix probe sets: Gga.6271.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000064131
Ensembl peptide - ENSGALP00000026742
Ensembl peptide - ENSGALP00000062705
Ensembl peptide - ENSGALP00000063133
NCBI entrez gene - 422011     See in Manteia.
RefSeq - NM_001031098
RefSeq - XM_015285103
RefSeq Peptide - NP_001026269
swissprot - F1NGL2
Ensembl - ENSGALG00000016600
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pomcaENSDARG00000043135Danio rerio
 pomcbENSDARG00000069307Danio rerio
 POMCENSG00000115138Homo sapiens
 PomcENSMUSG00000020660Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001941  Pro-opiomelanocortin
 IPR013531  Pro-opiomelanocortin/corticotropin, ACTH, central region
 IPR013532  Opiodes neuropeptide
 IPR013593  Pro-opiomelanocortin N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006091 generation of precursor metabolites and energy IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007218 neuropeptide signaling pathway IBA
 biological_processGO:0007267 cell-cell signaling IEA
 biological_processGO:0008217 regulation of blood pressure IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0032098 regulation of appetite IEA
 biological_processGO:0032720 negative regulation of tumor necrosis factor production IEA
 biological_processGO:0033059 cellular pigmentation IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0070873 regulation of glycogen metabolic process IEA
 biological_processGO:2000852 regulation of corticosterone secretion IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0030141 secretory granule IBA
 molecular_functionGO:0001664 G-protein coupled receptor binding IBA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0005184 neuropeptide hormone activity IBA
 molecular_functionGO:0031781 type 3 melanocortin receptor binding IEA
 molecular_functionGO:0031782 type 4 melanocortin receptor binding IEA
 molecular_functionGO:0070996 type 1 melanocortin receptor binding IEA


Pathways (from Reactome)
Pathway description
Opioid Signalling
Androgen biosynthesis
G-protein activation
Peptide hormone biosynthesis
Peptide ligand-binding receptors
G alpha (s) signalling events
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000014681 PCSK1 / proprotein convertase subtilisin/kexin type 1 / P29120* / P63239* / Neuroendocrine convertase 1 *  / reaction
 ENSGALG00000032087 MC5R / melanocortin receptor 5 / P33032* / melanocortin 5 receptor*  / complex / reaction
 ENSGALG00000001334 GNB1 / G protein subunit beta 1 / P62873* / P62874* / guanine nucleotide binding protein (G protein), beta 1*  / reaction / complex
 ENSGALG00000027260 MC3R / melanocortin 3 receptor / P33033* / P41968* / Melanocortin receptor 3 *  / reaction / complex
 ENSGALG00000027629 GNG2 / G protein subunit gamma 2 / P59768* / P63213* / guanine nucleotide binding protein (G protein), gamma 2*  / complex / reaction
 ENSGALG00000035569 MC2R / adrenocorticotropic hormone receptor / Q01718* / Q64326* / melanocortin 2 receptor*  / reaction / complex






 

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