ENSDARG00000055377


Danio rerio

Features
Gene ID: ENSDARG00000055377
  
Biological name :gnb5b
  
Synonyms : gnb5b / guanine nucleotide binding protein (G protein), beta 5b / Q6PBY0
  
Possible biological names infered from orthology : GNB5 / G protein subunit beta 5 / guanine nucleotide binding protein (G protein), beta 5 / O14775 / P62881
  
Species: Danio rerio
  
Chr. number: 18
Strand: 1
Band:
Gene start: 39067575
Gene end: 39105519
  
Corresponding Affymetrix probe sets: Dr.9903.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000072190
Ensembl peptide - ENSDARP00000113211
NCBI entrez gene - 393719     See in Manteia.
swissprot - F1R9V4
swissprot - Q6PBY0
ZFIN ID - ZDB-GENE-040426-1712
Ensembl - ENSDARG00000055377
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GNB5ENSGALG00000039307Gallus gallus
 GNB5ENSG00000069966Homo sapiens
 Gnb5ENSMUSG00000032192Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gnb5a / A1L271 / guanine nucleotide binding protein (G protein), beta 5a / GNB5* / P62881* / O14775* / G protein subunit beta 5* / guanine nucleotide binding protein (G protein), beta 5*ENSDARG0000009968580
gnb1a / Q6PH57 / guanine nucleotide binding protein (G protein), beta polypeptide 1a / GNB1* / P62873* / G protein subunit beta 1*ENSDARG0000009045446
gnb1b / guanine nucleotide binding protein (G protein), beta polypeptide 1b / GNB1* / P62874* / P62873* / G protein subunit beta 1* / guanine nucleotide binding protein (G protein), beta 1*ENSDARG0000010437246
gnb4b / guanine nucleotide binding protein (G protein), beta polypeptide 4b / GNB4* / Q9HAV0* / G protein subunit beta 4*ENSDARG0000011538345
gnb2 / guanine nucleotide binding protein (G protein), beta polypeptide 2 / P62880* / P62879* / G protein subunit beta 2* / guanine nucleotide binding protein (G protein), beta 2*ENSDARG0000003535745
gnb3a / guanine nucleotide binding protein (G protein), beta polypeptide 3a / GNB3* / Q61011* / P16520* / G protein subunit beta 3* / guanine nucleotide binding protein (G protein), beta 3*ENSDARG0000000435842
gnb3b / guanine nucleotide binding protein (G protein), beta polypeptide 3b / GNB3* / Q61011* / P16520* / G protein subunit beta 3* / guanine nucleotide binding protein (G protein), beta 3*ENSDARG0000000269641
GNB4 / G protein subunit beta 4 / Q9HAV0*ENSDARG0000001927830
wdr47a / WD repeat domain 47a / WDR47* / Q8CGF6* / O94967* / WD repeat domain 47*ENSDARG0000007813626
wdr47b / WD repeat domain 47b / WDR47* / O94967* / WD repeat domain 47*ENSDARG0000009975725


Protein motifs (from Interpro)
Interpro ID Name
 IPR001632  G-protein, beta subunit
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA


Pathways (from Reactome)
Pathway description
G-protein activation
Inactivation, recovery and regulation of the phototransduction cascade
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000016584 rgs7a / regulator of G protein signaling 7a / RGS7* / O54829* / P49802* / regulator of G protein signaling 7*  / complex / reaction
 ENSDARG00000045156 rgs9b / regulator of G protein signaling 9b / RGS9* / O54828* / O75916* / regulator of G protein signaling 9*  / reaction / complex
 ENSDARG00000086756 RGS9BP / si:ch73-167i17.6 / Q6ZS82* / regulator of G protein signaling 9 binding protein*  / complex
 ENSDARG00000009480 pdcl / phosducin-like / Q13371* / Q9DBX2* / Phosducin-like protein *  / complex






 

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