ENSDARG00000019342


Danio rerio

Features
Gene ID: ENSDARG00000019342
  
Biological name :chrnd
  
Synonyms : cholinergic receptor, nicotinic, delta (muscle) / chrnd
  
Possible biological names infered from orthology : cholinergic receptor, nicotinic, delta polypeptide / cholinergic receptor nicotinic delta subunit / P02716 / Q07001
  
Species: Danio rerio
  
Chr. number: 24
Strand: -1
Band:
Gene start: 25683071
Gene end: 25691020
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000016537
NCBI entrez gene - 404273     See in Manteia.
RefSeq - NM_207064
RefSeq Peptide - NP_996947
swissprot - Q75XT1
ZFIN ID - ZDB-GENE-030131-6665
Ensembl - ENSDARG00000019342
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CHRNDENSGALG00000007899Gallus gallus
 CHRNDENSG00000135902Homo sapiens
 ChrndENSMUSG00000026251Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
chrne / cholinergic receptor, nicotinic, epsilon / P20782* / Q04844* / cholinergic receptor nicotinic epsilon subunit* / cholinergic receptor, nicotinic, epsilon polypeptide*ENSDARG0000003430748
chrng / cholinergic receptor, nicotinic, gamma / P07510* / cholinergic receptor nicotinic gamma subunit*ENSDARG0000008664745
chrnb1l / cholinergic receptor, nicotinic, beta 1 (muscle) like / CHRNB1* / P09690* / P11230* / cholinergic receptor nicotinic beta 1 subunit* / cholinergic receptor, nicotinic, beta polype...ENSDARG0000002253239
chrnb1 / cholinergic receptor, nicotinic, beta 1 (muscle) / P09690* / P11230* / cholinergic receptor nicotinic beta 1 subunit* / cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)*ENSDARG0000006966037
chrna7 / cholinergic receptor, nicotinic, alpha 7 (neuronal) / Q494W8* / P36544* / P49582* / CHRFAM7A* / cholinergic receptor nicotinic alpha 7 subunit* / CHRNA7 (exons 5-10) and FAM7A (exo...ENSDARG0000010170232
FO907089.1 / Q494W8* / CHRNA7* / P36544* / CHRFAM7A* / cholinergic receptor nicotinic alpha 7 subunit* / CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion*ENSDARG0000010152232
si:ch73-380n15.2ENSDARG0000008722430
si:ch211-39a7.1ENSDARG0000003742728
chrna10a / cholinergic receptor, nicotinic, alpha 10aENSDARG0000001111326
chrna9 / cholinergic receptor, nicotinic, alpha 9 / Q9UGM1* / cholinergic receptor nicotinic alpha 9 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 9*ENSDARG0000005468026
CR847523.1ENSDARG0000010811826
LO018568.1 / CHRNA9* / Q9UGM1* / cholinergic receptor nicotinic alpha 9 subunit*ENSDARG0000009918124
htr3a / 5-hydroxytryptamine (serotonin) receptor 3A / P46098* / 5-hydroxytryptamine receptor 3A*ENSDARG0000008921218
FO818743.1ENSDARG0000010267517
htr3b / 5-hydroxytryptamine (serotonin) receptor 3B / O95264* / Q9JHJ5* / 5-hydroxytryptamine receptor 3B*ENSDARG0000006174917
si:ch211-256e16.4ENSDARG0000007842815
si:ch211-256e16.6ENSDARG0000007960314
HTR3C / 5-hydroxytryptamine receptor 3C / HTR3D* / HTR3E* / A5X5Y0* / Q8WXA8* / Q70Z44* / 5-hydroxytryptamine receptor 3D* / 5-hydroxytryptamine receptor 3E*ENSDARG0000007795914
si:dkey-49c17.4ENSDARG0000007482410
si:ch211-256e16.10ENSDARG0000009756610


Protein motifs (from Interpro)
Interpro ID Name
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007271 synaptic transmission, cholinergic IBA
 biological_processGO:0007274 neuromuscular synaptic transmission IBA
 biological_processGO:0030239 myofibril assembly IMP
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0035094 response to nicotine IBA
 biological_processGO:0060078 regulation of postsynaptic membrane potential IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005892 acetylcholine-gated channel complex IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0022848 acetylcholine-gated cation-selective channel activity IMP
 molecular_functionGO:0042166 acetylcholine binding IBA


Pathways (from Reactome)
Pathway description
Highly sodium permeable acetylcholine nicotinic receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain quality , abnormal
Show

 ZFA:0000026 hatching gland hatching gland quality , abnormal
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 ZFA:0000155 somite somite fast muscle cell decreased size , abnormal
somite fast muscle cell degenerate , abnormal
somite slow muscle cell morphology , abnormal
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 ZFA:0000396 nervous system nervous system quality , abnormal
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 ZFA:0001056 myotome myotome skeletal muscle cell atrophied , abnormal
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 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
whole organism viability , abnormal
whole organism immobile , abnormal
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 ZFA:0001135 neural tube neural tube quality , abnormal
neural tube morphology , abnormal
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 ZFA:0005277 skeletal muscle skeletal muscle acetylcholine-gated channel complex absent , abnormal
skeletal muscle potassium channel complex decreased amount , abnormal
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 ZFA:0009115 skeletal muscle cell skeletal muscle cell acetylcholine-gated channel complex position , abnormal
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 ZFA:0009116 slow muscle cell slow muscle cell membrane potential , abnormal
slow muscle cell myosin complex decreased object quality , abnormal
slow muscle cell myofibril decreased diameter , abnormal
slow muscle cell neuromuscular synaptic transmission decreased magnitude , abnormal
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 ZFA:0009117 fast muscle cell fast muscle cell myosin complex decreased object quality , abnormal
fast muscle cell acetylcholine-gated channel complex non-functional , abnormal
fast muscle cell neuromuscular synaptic transmission arrested , abnormal
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 ZFA:0009247 secondary motor neuron secondary motor neuron axon branched , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000101677 chrnb4 / cholinergic receptor, nicotinic, beta 4 (neuronal) / P30926* / Q8R493* / cholinergic receptor nicotinic beta 4 subunit* / cholinergic receptor, nicotinic, beta polypeptide 4*  / complex






 

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