ENSDARG00000020708


Danio rerio

Features
Gene ID: ENSDARG00000020708
  
Biological name :mdkb
  
Synonyms : mdkb / midkine b
  
Possible biological names infered from orthology : MDK / midkine / P12025 / P21741
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 7872135
Gene end: 7880878
  
Corresponding Affymetrix probe sets: Dr.24241.1.S1_at (Zebrafish Array)   NM_131716_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000018513
NCBI entrez gene - 65231     See in Manteia.
RefSeq - NM_131716
RefSeq Peptide - NP_571791
swissprot - Q9DDG2
ZFIN ID - ZDB-GENE-010131-6
Ensembl - ENSDARG00000020708
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MDKENSGALG00000008367Gallus gallus
 MDKENSG00000110492Homo sapiens
 MdkENSMUSG00000027239Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mdka / midkine a / MDK* / P21741* / P12025* / midkine*ENSDARG0000003603662
ptn / pleiotrophin / P21246* / P63089*ENSDARG0000010234041


Protein motifs (from Interpro)
Interpro ID Name
 IPR000762  Midkine heparin-binding growth factor
 IPR020089  Pleiotrophin/Midkine, N-terminal domain
 IPR020090  Pleiotrophin/Midkine, C-terminal domain
 IPR020091  Pleiotrophin/Midkine disulphide-rich domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007399 nervous system development IMP
 biological_processGO:0007420 brain development IMP
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0014029 neural crest formation IMP
 biological_processGO:0045666 positive regulation of neuron differentiation IMP
 cellular_componentGO:0005576 extracellular region IDA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
NOTCH2 Activation and Transmission of Signal to the Nucleus


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000068 proneural cluster proneural cluster decreased size , abnormal
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 ZFA:0009053 sensory neuron sensory neuron decreased amount , abnormal
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 ZFA:0009150 Rohon-Beard neuron Rohon-Beard neuron decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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