ENSGALG00000008367


Gallus gallus

Features
Gene ID: ENSGALG00000008367
  
Biological name :MDK
  
Synonyms : MDK / midkine precursor
  
Possible biological names infered from orthology : midkine / P12025 / P21741
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 23648664
Gene end: 23650689
  
Corresponding Affymetrix probe sets: Gga.5002.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000013607
Ensembl peptide - ENSGALP00000063721
Ensembl peptide - ENSGALP00000060817
NCBI entrez gene - 423196     See in Manteia.
RefSeq - XM_015287039
RefSeq - XM_015287041
RefSeq - NM_001113289
RefSeq - XM_015287040
RefSeq Peptide - NP_001106760
swissprot - A9DAB9
swissprot - A0A1L1RXZ9
Ensembl - ENSGALG00000008367
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mdkaENSDARG00000036036Danio rerio
 mdkbENSDARG00000020708Danio rerio
 MDKENSG00000110492Homo sapiens
 MdkENSMUSG00000027239Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTN / pleiotrophin / P21246* / P63089*ENSGALG0000004049348


Protein motifs (from Interpro)
Interpro ID Name
 IPR000762  Midkine heparin-binding growth factor
 IPR020089  Pleiotrophin/Midkine, N-terminal domain
 IPR020090  Pleiotrophin/Midkine, C-terminal domain
 IPR020091  Pleiotrophin/Midkine disulphide-rich domain superfamily
 IPR020092  Pleiotrophin/Midkine heparin-binding growth factor, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001662 behavioral fear response IEA
 biological_processGO:0007614 short-term memory IEA
 biological_processGO:0009611 response to wounding IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0021542 dentate gyrus development IEA
 biological_processGO:0021681 cerebellar granular layer development IEA
 biological_processGO:0021766 hippocampus development IEA
 biological_processGO:0021987 cerebral cortex development IEA
 biological_processGO:0030421 defecation IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0050795 regulation of behavior IEA
 biological_processGO:1901215 negative regulation of neuron death IEA
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0008201 heparin binding IEA


Pathways (from Reactome)
Pathway description
NOTCH2 Activation and Transmission of Signal to the Nucleus


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002922 NOTCH2 / Q04721*  / reaction / complex
 ENSGALG00000008367 MDK / midkine precursor / P12025* / P21741* / midkine*  / complex






 

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