ENSDARG00000021442


Danio rerio

Features
Gene ID: ENSDARG00000021442
  
Biological name :cdh11
  
Synonyms : cadherin 11, type 2, OB-cadherin (osteoblast) / cdh11
  
Possible biological names infered from orthology : cadherin 11 / P55287 / P55288
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 43760149
Gene end: 43857938
  
Corresponding Affymetrix probe sets: Dr.21810.1.A1_at (Zebrafish Array)   Dr.251.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000151942
Ensembl peptide - ENSDARP00000153918
Ensembl peptide - ENSDARP00000006449
Ensembl peptide - ENSDARP00000143868
NCBI entrez gene - 30461     See in Manteia.
RefSeq - XM_005166446
RefSeq - XM_021477391
RefSeq - XM_021477392
RefSeq Peptide - NP_571289
swissprot - B3DGG4
ZFIN ID - ZDB-GENE-980526-170
Ensembl - ENSDARG00000021442
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CDH11ENSGALG00000039985Gallus gallus
 CDH11ENSG00000140937Homo sapiens
 Cdh11ENSMUSG00000031673Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cdh7a / cadherin 7a / CDH7* / Q8BM92* / Q9ULB5* / cadherin 7*ENSDARG0000002354255
cdh10a / cadherin 10, type 2a (T2-cadherin) / CDH6* / CDH9* / CDH10* / Q9Y6N8* / P70408* / P97326* / Q9ULB4* / P55285* / cadherin 9* / cadherin 6* / cadherin 10*ENSDARG0000005584353
CDH18 / cadherin 18 / Q13634*ENSDARG0000010276952
cdh12a / cadherin 12, type 2a (N-cadherin 2) / CDH12* / P55289* / Q5RJH3* / cadherin 12*ENSDARG0000007822649
cdh6 / cadherin 6 / CDH9* / CDH10* / Q9Y6N8* / P97326* / Q9ULB4* / P55285* / P70408* / cadherin 9* / cadherin 10*ENSDARG0000001452249
CDH22 / cadherin 22 / Q9UJ99*ENSDARG0000009882446
cdh24b / cadherin 24, type 2b / CDH24* / Q6PFX6* / Q86UP0* / cadherin 24*ENSDARG0000007799644
LO017650.1 / CDH9* / CDH6* / CDH10* / Q9Y6N8* / P70408* / P97326* / Q9ULB4* / P55285* / cadherin 9* / cadherin 6* / cadherin 10*ENSDARG0000010390341
CABZ01109081.1 / CDH19* / Q9H159* / cadherin 19*ENSDARG0000010059836
cdh7b / cadherin 7b / CDH7* / Q9ULB5* / cadherin 7*ENSDARG0000001764936


Protein motifs (from Interpro)
Interpro ID Name
 IPR000233  Cadherin, cytoplasmic domain
 IPR002126  Cadherin
 IPR015919  Cadherin-like
 IPR020894  Cadherin conserved site
 IPR027397  Catenin binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IEA
 biological_processGO:0031290 retinal ganglion cell axon guidance IMP
 biological_processGO:0048840 otolith development IMP
 biological_processGO:0060041 retina development in camera-type eye IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Adherens junctions interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000024 retinal ganglion cell layer retinal ganglion cell layer has fewer parts of type retinal ganglion cell , abnormal
retinal ganglion cell layer decreased thickness , abnormal
retinal ganglion cell layer disorganized , abnormal
Show

 ZFA:0000029 hindbrain hindbrain morphology , abnormal
hindbrain cell cellular adhesivity hindbrain cell, abnormal
Show

 ZFA:0000035 lens lens decreased size , abnormal
lens disorganized , abnormal
Show

 ZFA:0000051 otic vesicle otic vesicle morphology , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000119 retinal inner nuclear layer retinal inner nuclear layer has fewer parts of type amacrine cell , abnormal
Show

 ZFA:0000137 optic stalk optic stalk shape , abnormal
optic stalk decreased size , abnormal
Show

 ZFA:0000152 retina retina morphology , abnormal
retina disorganized , abnormal
retina apoptotic process increased occurrence , abnormal
Show

 ZFA:0000217 inner ear inner ear decreased size , abnormal
Show

 ZFA:0000386 macula macula morphology , abnormal
Show

 ZFA:0000435 cranial nerve II cranial nerve II decreased thickness , abnormal
cranial nerve II physical object quality , abnormal
Show

 ZFA:0000445 optic tectum optic tectum has fewer parts of type retinal ganglion cell neuron projection, abnormal
Show

 ZFA:0000534 lateral longitudinal fasciculus lateral longitudinal fasciculus decreased size , abnormal
Show

 ZFA:0000543 medial longitudinal fasciculus medial longitudinal fasciculus decreased size , abnormal
Show

 ZFA:0000823 rhombomere 5 rhombomere 5 shape , abnormal
Show

 ZFA:0000948 rhombomere 3 rhombomere 3 shape , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
Show

 ZFA:0001117 post-vent region post-vent region increased curvature , abnormal
post-vent region cystic , abnormal
post-vent region cell cellular adhesivity post-vent region cell, abnormal
Show

 ZFA:0001617 otolith otolith decreased size , abnormal
otolith decreased amount , abnormal
Show

 ZFA:0009310 retinal ganglion cell retinal ganglion cell neuron projection mislocalised , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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