ENSDARG00000023678


Danio rerio

Features
Gene ID: ENSDARG00000023678
  
Biological name :ercc5
  
Synonyms : ercc5 / excision repair cross-complementation group 5
  
Possible biological names infered from orthology : ERCC excision repair 5, endonuclease / P28715
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 474085
Gene end: 494280
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000033024
Ensembl peptide - ENSDARP00000123630
Ensembl peptide - ENSDARP00000148316
NCBI entrez gene - 541502     See in Manteia.
RefSeq - XM_003197605
swissprot - F1QB77
swissprot - F1QJS3
swissprot - Q58EB6
ZFIN ID - ZDB-GENE-050327-28
Ensembl - ENSDARG00000023678
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ERCC5ENSGALG00000016860Gallus gallus
 ERCC5ENSG00000134899Homo sapiens
 Ercc5ENSMUSG00000026048Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001044  XPG/Rad2 endonuclease, eukaryotes
 IPR006084  XPG/Rad2 endonuclease
 IPR006085  XPG N-terminal
 IPR006086  XPG-I domain
 IPR008918  Helix-hairpin-helix motif, class 2
 IPR019974  XPG conserved site
 IPR020045  DNA polymerase I-like, H3TH domain
 IPR029060  PIN-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006289 nucleotide-excision repair IEA
 biological_processGO:0006295 nucleotide-excision repair, DNA incision, 3"-to lesion IBA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003697 single-stranded DNA binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0004520 endodeoxyribonuclease activity IBA
 molecular_functionGO:0016788 hydrolase activity, acting on ester bonds IEA


Pathways (from Reactome)
Pathway description
Formation of Incision Complex in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003938 rpa1 / Q6NY74 / replication protein A1 / Q8VEE4* / P27694* / Replication protein A 70 kDa DNA-binding subunit *  / reaction / complex
 ENSDARG00000031680 ercc1 / excision repair cross-complementation group 1 / P07992* / P07903* / DNA excision repair protein ERCC-1 * / ERCC excision repair 1, endonuclease non-catalytic subunit*  / complex / reaction
 ENSDARG00000037188 rpa2 / replication protein A2 / RPA4* / Q13156* / P15927* / replication protein A4*  / reaction / complex






 

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