ENSGALG00000016860


Gallus gallus

Features
Gene ID: ENSGALG00000016860
  
Biological name :ERCC5
  
Synonyms : DNA repair protein complementing XP-G cells / ERCC5
  
Possible biological names infered from orthology : ERCC excision repair 5, endonuclease / P28715
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 142756384
Gene end: 142771448
  
Corresponding Affymetrix probe sets: Gga.16086.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000027186
NCBI entrez gene - 428019     See in Manteia.
RefSeq - XM_015274521
RefSeq - NM_001034823
RefSeq - XM_015274512
RefSeq - XM_015274516
RefSeq Peptide - NP_001029995
swissprot - F1P266
Ensembl - ENSGALG00000016860
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ercc5ENSDARG00000023678Danio rerio
 ERCC5ENSG00000134899Homo sapiens
 Ercc5ENSMUSG00000026048Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001044  XPG/Rad2 endonuclease, eukaryotes
 IPR006084  XPG/Rad2 endonuclease
 IPR006085  XPG N-terminal
 IPR006086  XPG-I domain
 IPR008918  Helix-hairpin-helix motif, class 2
 IPR019974  XPG conserved site
 IPR020045  DNA polymerase I-like, H3TH domain
 IPR029060  PIN-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006283 transcription-coupled nucleotide-excision repair IEA
 biological_processGO:0006289 nucleotide-excision repair IEA
 biological_processGO:0006295 nucleotide-excision repair, DNA incision, 3"-to lesion IEA
 biological_processGO:0009411 response to UV IEA
 biological_processGO:0009650 UV protection IEA
 biological_processGO:0010225 response to UV-C IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005662 DNA replication factor A complex IEA
 cellular_componentGO:0005675 holo TFIIH complex IEA
 cellular_componentGO:0016591 DNA-directed RNA polymerase II, holoenzyme IEA
 molecular_functionGO:0000405 bubble DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IEA
 molecular_functionGO:0003697 single-stranded DNA binding IBA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0004520 endodeoxyribonuclease activity IEA
 molecular_functionGO:0016788 hydrolase activity, acting on ester bonds IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0047485 protein N-terminus binding IEA


Pathways (from Reactome)
Pathway description
Formation of Incision Complex in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000734 RPA2 / RPA4* / Q13156* / P15927* / replication protein A2* / replication protein A4*  / complex / reaction
 ENSGALG00000003072 RPA1 / Q5ZJJ2 / Replication protein A 70 kDa DNA-binding subunit / Q8VEE4* / P27694* / replication protein A1*  / reaction / complex
 ENSGALG00000010700 RPA3 / replication protein A3 / P35244* / Q9CQ71* / Replication protein A 14 kDa subunit *  / complex / reaction






 

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