ENSDARG00000023914


Danio rerio

Features
Gene ID: ENSDARG00000023914
  
Biological name :mark4a
  
Synonyms : MAP/microtubule affinity-regulating kinase 4a / mark4a
  
Possible biological names infered from orthology : MAP/microtubule affinity-regulating kinase 4 / MARK4 / microtubule affinity regulating kinase 4 / Q8CIP4 / Q96L34
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 36768674
Gene end: 36822220
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000081625
Ensembl peptide - ENSDARP00000121243
swissprot - A2BHA2
swissprot - F1Q5N2
ZFIN ID - ZDB-GENE-060531-156
Ensembl - ENSDARG00000023914
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MARK4ENSG00000007047Homo sapiens
 Mark4ENSMUSG00000030397Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MARK4 / si:dkey-31m14.7 / Q96L34* / Q8CIP4* / microtubule affinity regulating kinase 4* / MAP/microtubule affinity-regulating kinase 4 *ENSDARG0000002496671
mark3b / MAP/microtubule affinity-regulating kinase 3b / MARK1* / MARK3* / P27448* / Q9P0L2* / Q8VHJ5* / Q03141* / Serine/threonine-protein kinase MARK1 * / microtubule affinity regulating ...ENSDARG0000002663059
mark3a / MAP/microtubule affinity-regulating kinase 3aENSDARG0000001934554
mark2b / MAP/microtubule affinity-regulating kinase 2b / MARK2* / Q7KZI7* / microtubule affinity regulating kinase 2*ENSDARG0000003245850
mark2a / MAP/microtubule affinity-regulating kinase 2a / MARK2* / Q7KZI7* / microtubule affinity regulating kinase 2*ENSDARG0000007990550
mark1 / MAP/microtubule affinity-regulating kinase 1ENSDARG0000010401444
sik2b / salt-inducible kinase 2b / SIK2* / Q9H0K1* / salt inducible kinase 2*ENSDARG0000006231528
sik1 / salt-inducible kinase 1 / SIK1B* / Q60670* / P57059* / salt inducible kinase 1B (putative)* / Serine/threonine-protein kinase SIK1 *ENSDARG0000005860627
sik2a / salt-inducible kinase 2a / SIK2* / Q9H0K1* / salt inducible kinase 2*ENSDARG0000007961827
sik3 / SIK family kinase 3ENSDARG0000008808326
snrka / SNF related kinase a / SNRK* / Q9NRH2* / SNF related kinase*ENSDARG0000007083226
snrkb / SNF related kinase bENSDARG0000001766521
nim1k / NIM1 serine/threonine protein kinase / Q8BHI9* / Q8IY84* / Serine/threonine-protein kinase NIM1 *ENSDARG0000007408719
si:ch211-22d5.2ENSDARG0000007903119


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001772  Kinase associated domain 1 (KA1)
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR015940  Ubiquitin-associated domain
 IPR017441  Protein kinase, ATP binding site
 IPR028375  KA1 domain/Ssp2, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030010 establishment of cell polarity IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Anchoring of the basal body to the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000005670 ttbk2a / tau tubulin kinase 2a / TTBK2* / Q3UVR3* / Q6IQ55* / tau tubulin kinase 2*  / reaction / complex
 ENSDARG00000043026 ttbk2b / tau tubulin kinase 2b / TTBK2* / Q3UVR3* / Q6IQ55* / tau tubulin kinase 2*  / complex / reaction






 

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