ENSDARG00000025285


Danio rerio

Features
Gene ID: ENSDARG00000025285
  
Biological name :panx1a
  
Synonyms : pannexin 1a / panx1a
  
Possible biological names infered from orthology : pannexin 1 / PANX1 / Q96RD7 / Q9JIP4
  
Species: Danio rerio
  
Chr. number: 15
Strand: 1
Band:
Gene start: 2475894
Gene end: 2489934
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000034149
swissprot - F1R791
ZFIN ID - ZDB-GENE-040426-766
Ensembl - ENSDARG00000025285
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PANX1ENSGALG00000039751Gallus gallus
 PANX1ENSG00000110218Homo sapiens
 Panx1ENSMUSG00000031934Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
panx1b / pannexin 1b / PANX1* / Q96RD7* / Q9JIP4* / pannexin 1*ENSDARG0000001491057
panx3 / pannexin 3 / Q8CEG0* / Q96QZ0*ENSDARG0000000462734
panx2 / pannexin 2 / Q6IMP4* / Q96RD6*ENSDARG0000006301921


Protein motifs (from Interpro)
Interpro ID Name
 IPR000990  Innexin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IBA
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005921 gap junction IEA
 cellular_componentGO:0012505 endomembrane system IBA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0032587 ruffle membrane IDA
 molecular_functionGO:0015267 channel activity IDA
 molecular_functionGO:0022829 wide pore channel activity IDA
 molecular_functionGO:0022832 voltage-gated channel activity IDA
 molecular_functionGO:0055077 gap junction hemi-channel activity IDA


Pathways (from Reactome)
Pathway description
Electric Transmission Across Gap Junctions
The NLRP3 inflammasome


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain microglial cell decreased amount , abnormal
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 ZFA:0000029 hindbrain hindbrain microglial cell amount , ameliorated
hindbrain neuron decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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