ENSGALG00000039751


Gallus gallus

Features
Gene ID: ENSGALG00000039751
  
Biological name :PANX1
  
Synonyms : pannexin 1 / PANX1
  
Possible biological names infered from orthology : Q96RD7 / Q9JIP4
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 185732435
Gene end: 185751184
  
Corresponding Affymetrix probe sets: GgaAffx.25200.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046158
Ensembl peptide - ENSGALP00000056008
Ensembl peptide - ENSGALP00000054642
NCBI entrez gene - 772164     See in Manteia.
RefSeq - XM_015280513
RefSeq - XM_015280516
swissprot - A0A1D5PSW8
swissprot - A0A1D5PP45
swissprot - A0A1D5P0I0
Ensembl - ENSGALG00000039751
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 panx1aENSDARG00000025285Danio rerio
 panx1bENSDARG00000014910Danio rerio
 PANX1ENSG00000110218Homo sapiens
 Panx1ENSMUSG00000031934Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PANX3 / pannexin 3 / Q8CEG0* / Q96QZ0*ENSGALG0000002144336
PANX2 / pannexin 2 / Q6IMP4* / Q96RD6*ENSGALG0000000000317


Protein motifs (from Interpro)
Interpro ID Name
 IPR000990  Innexin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002931 response to ischemia IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0033198 response to ATP IEA
 biological_processGO:0034214 protein hexamerization IEA
 biological_processGO:0050715 positive regulation of cytokine secretion IEA
 biological_processGO:0050717 positive regulation of interleukin-1 alpha secretion IEA
 biological_processGO:0050718 positive regulation of interleukin-1 beta secretion IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005921 gap junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0032059 bleb IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005262 calcium channel activity IEA
 molecular_functionGO:0015267 channel activity IEA
 molecular_functionGO:0022840 leak channel activity IEA
 molecular_functionGO:0051015 actin filament binding IEA
 molecular_functionGO:0055077 gap junction hemi-channel activity IEA


Pathways (from Reactome)
Pathway description
Electric Transmission Across Gap Junctions
The NLRP3 inflammasome


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003863 P2RX7 / purinergic receptor P2X 7 / Q99572* / Q9Z1M0* / P2X purinoceptor 7 *  / complex
 ENSGALG00000000003 PANX2 / pannexin 2 / Q6IMP4* / Q96RD6*  / complex
 ENSGALG00000039751 PANX1 / pannexin 1 / Q96RD7* / Q9JIP4*  / complex






 

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