ENSDARG00000025567


Danio rerio

Features
Gene ID: ENSDARG00000025567
  
Biological name :nf2b
  
Synonyms : neurofibromin 2b (merlin) / nf2b
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 25801345
Gene end: 25819707
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000112172
Ensembl peptide - ENSDARP00000113200
Ensembl peptide - ENSDARP00000035057
NCBI entrez gene - 405887     See in Manteia.
RefSeq - NM_212951
RefSeq Peptide - NP_998116
swissprot - E9QGK2
swissprot - Q6Q413
ZFIN ID - ZDB-GENE-040622-3
Ensembl - ENSDARG00000025567
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000002367Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nf2a / neurofibromin 2a (merlin) / NF2* / P35240* / P46662* / Merlin * / neurofibromin 2*ENSDARG0000002020469
ezrb / sytl3 / synaptotagmin-like 3 / EZR* / ezrin* / P15311* / P26040*ENSDARG0000002509142
msna / moesin a / MSN* / moesin* / P26038* / P26041*ENSDARG0000005812841
ezra / ezrin a / EZR* / ezrin* / P15311* / P26040*ENSDARG0000002094440
msnb / moesin b / MSN* / moesin* / P26038* / P26041*ENSDARG0000002874039
farp2 / FERM, RhoGEF and pleckstrin domain protein 2 / O94887* / Q91VS8* / FERM, ARH/RhoGEF and pleckstrin domain protein 2* / FERM, ARHGEF and pleckstrin domain-containing protein 2 *ENSDARG0000001642921
farp1 / FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) / Q9Y4F1* / F8VPU2* / FERM, ARH/RhoGEF and pleckstrin domain protein 1* / FERM, ARHGEF and pleckstrin dom...ENSDARG0000007438121
frmd7 / FERM domain containing 7 / A2AD83* / Q6ZUT3* / FERM domain-containing protein 7 *ENSDARG0000006895814
mylipa / Q6TEM9 / myosin regulatory light chain interacting protein a / MYLIP* / Q8BM54* / Q8WY64* / E3 ubiquitin-protein ligase MYLIP * / myosin regulatory light chain interacting protein*ENSDARG0000000885914
mylipb / myosin regulatory light chain interacting protein b / MYLIP* / Q8BM54* / Q8WY64* / E3 ubiquitin-protein ligase MYLIP * / myosin regulatory light chain interacting protein*ENSDARG0000005511813
si:ch211-243g6.3 / FRMD7* / A2AD83* / Q6ZUT3* / FERM domain containing 7* / FERM domain-containing protein 7 *ENSDARG0000007049513
CABZ01066921.1ENSDARG0000011205611


Protein motifs (from Interpro)
Interpro ID Name
 IPR000299  FERM domain
 IPR000798  Ezrin/radixin/moesin-like
 IPR008954  Moesin tail domain superfamily
 IPR011174  Ezrin/radixin/moesin
 IPR011259  Ezrin/radixin/moesin, C-terminal
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR018979  FERM, N-terminal
 IPR018980  FERM, C-terminal PH-like domain
 IPR019747  FERM conserved site
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005856 cytoskeleton IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0008092 cytoskeletal protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000109 forebrain forebrain decreased size , abnormal
Show

 ZFA:0000112 gut gut quality , abnormal
gut hypoplastic , abnormal
Show

 ZFA:0000123 liver liver increased size , abnormal
liver quality , abnormal
Show

 ZFA:0000208 gall bladder gall bladder dilated , abnormal
gall bladder quality , abnormal
Show

 ZFA:0001094 whole organism whole organism shape , abnormal
whole organism bent , abnormal
Show

 ZFA:0001114 head head decreased width , abnormal
Show

 ZFA:0001115 trunk trunk bent , abnormal
Show

 ZFA:0001439 anatomical system anatomical system quality , abnormal
Show

 ZFA:0005165 common bile duct common bile duct morphology , abnormal
common bile duct dilated , abnormal
common bile duct cystic , abnormal
Show

 ZFA:0009111 hepatocyte hepatocyte increased distance hepatocyte , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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