ENSDARG00000074381


Danio rerio

Features
Gene ID: ENSDARG00000074381
  
Biological name :farp1
  
Synonyms : farp1 / FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
  
Possible biological names infered from orthology : F8VPU2 / FERM, ARHGEF and pleckstrin domain-containing protein 1 / FERM, ARH/RhoGEF and pleckstrin domain protein 1 / Q9Y4F1
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 2301958
Gene end: 2444210
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000115997
Ensembl peptide - ENSDARP00000140218
Ensembl peptide - ENSDARP00000157154
Ensembl peptide - ENSDARP00000098288
Ensembl peptide - ENSDARP00000113717
swissprot - B8JHS0
swissprot - B8JHS1
swissprot - E9QIC8
ZFIN ID - ZDB-GENE-070424-163
Ensembl - ENSDARG00000074381
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FARP1ENSGALG00000016886Gallus gallus
 FARP1ENSG00000152767Homo sapiens
 Farp1ENSMUSG00000025555Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
farp2 / FERM, RhoGEF and pleckstrin domain protein 2 / O94887* / Q91VS8* / FERM, ARH/RhoGEF and pleckstrin domain protein 2* / FERM, ARHGEF and pleckstrin domain-containing protein 2 *ENSDARG0000001642955
frmd7 / FERM domain containing 7 / A2AD83* / Q6ZUT3* / FERM domain-containing protein 7 *ENSDARG0000006895822
si:ch211-243g6.3 / FRMD7* / A2AD83* / Q6ZUT3* / FERM domain containing 7* / FERM domain-containing protein 7 *ENSDARG0000007049517
ezrb / sytl3 / synaptotagmin-like 3 / EZR* / ezrin* / P15311* / P26040*ENSDARG0000002509114
msna / moesin a / MSN* / moesin* / P26038* / P26041*ENSDARG0000005812814
ezra / ezrin a / EZR* / ezrin* / P15311* / P26040*ENSDARG0000002094414
msnb / moesin b / MSN* / moesin* / P26038* / P26041*ENSDARG0000002874013
nf2a / neurofibromin 2a (merlin) / NF2* / P35240* / P46662* / Merlin * / neurofibromin 2*ENSDARG0000002020412
nf2b / neurofibromin 2b (merlin)ENSDARG0000002556712
mylipa / Q6TEM9 / myosin regulatory light chain interacting protein a / MYLIP* / Q8BM54* / Q8WY64* / E3 ubiquitin-protein ligase MYLIP * / myosin regulatory light chain interacting protein*ENSDARG0000000885911
mylipb / myosin regulatory light chain interacting protein b / MYLIP* / Q8BM54* / Q8WY64* / E3 ubiquitin-protein ligase MYLIP * / myosin regulatory light chain interacting protein*ENSDARG0000005511810
CABZ01066921.1ENSDARG000001120568


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR000299  FERM domain
 IPR000798  Ezrin/radixin/moesin-like
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR014847  FERM adjacent (FA)
 IPR018979  FERM, N-terminal
 IPR018980  FERM, C-terminal PH-like domain
 IPR019747  FERM conserved site
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0008092 cytoskeletal protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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