ENSG00000152767


Homo sapiens

Features
Gene ID: ENSG00000152767
  
Biological name :FARP1
  
Synonyms : FARP1 / FERM, ARH/RhoGEF and pleckstrin domain protein 1 / Q9Y4F1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: 1
Band: q32.2
Gene start: 98142562
Gene end: 98455176
  
Corresponding Affymetrix probe sets: 201910_at (Human Genome U133 Plus 2.0 Array)   201911_s_at (Human Genome U133 Plus 2.0 Array)   227996_at (Human Genome U133 Plus 2.0 Array)   235501_at (Human Genome U133 Plus 2.0 Array)   237767_at (Human Genome U133 Plus 2.0 Array)   239246_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000472346
Ensembl peptide - ENSP00000471242
Ensembl peptide - ENSP00000486285
Ensembl peptide - ENSP00000490391
Ensembl peptide - ENSP00000322926
Ensembl peptide - ENSP00000365765
Ensembl peptide - ENSP00000410930
Ensembl peptide - ENSP00000469365
Ensembl peptide - ENSP00000469712
NCBI entrez gene - 10160     See in Manteia.
OMIM - 602654
RefSeq - XM_017020313
RefSeq - NM_001001715
RefSeq - NM_001286839
RefSeq - NM_005766
RefSeq - XM_011521046
RefSeq - XM_017020312
RefSeq Peptide - NP_001001715
RefSeq Peptide - NP_001273768
RefSeq Peptide - NP_005757
swissprot - C9JME2
swissprot - H0Y783
swissprot - M0QXT1
swissprot - M0QYB0
swissprot - M0R262
swissprot - Q9Y4F1
swissprot - A0A1B0GV68
Ensembl - ENSG00000152767
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 farp1ENSDARG00000074381Danio rerio
 FARP1ENSGALG00000016886Gallus gallus
 Farp1ENSMUSG00000025555Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FARP2 / O94887 / FERM, ARH/RhoGEF and pleckstrin domain protein 2ENSG0000000660753
FRMD7 / Q6ZUT3 / FERM domain containing 7ENSG0000016569426
MSN / moesin / P26038ENSG0000014706514
EZR / ezrin / P15311ENSG0000009282014
RDX / P35241 / radixinENSG0000013771014
NF2 / P35240 / neurofibromin 2ENSG0000018657512
MYLIP / Q8WY64 / myosin regulatory light chain interacting proteinENSG0000000794410


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR000299  FERM domain
 IPR000798  Ezrin/radixin/moesin-like
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR014847  FERM adjacent (FA)
 IPR018979  FERM, N-terminal
 IPR018980  FERM, C-terminal PH-like domain
 IPR019747  FERM conserved site
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR029071  Ubiquitin-like domain superfamily
 IPR035899  Dbl homology (DH) domain superfamily
 IPR035963  FERM superfamily, second domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007416 synapse assembly IEA
 biological_processGO:0010923 negative regulation of phosphatase activity IDA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0048813 dendrite morphogenesis IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030175 filopodium IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043197 dendritic spine IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0008092 cytoskeletal protein binding IEA
 molecular_functionGO:0030676 Rac guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0048365 Rac GTPase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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