ENSMUSG00000025555


Mus musculus

Features
Gene ID: ENSMUSG00000025555
  
Biological name :Farp1
  
Synonyms : F8VPU2 / Farp1 / FERM, ARHGEF and pleckstrin domain-containing protein 1
  
Possible biological names infered from orthology : FERM, ARH/RhoGEF and pleckstrin domain protein 1 / Q9Y4F1
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: E5
Gene start: 121035200
Gene end: 121283744
  
Corresponding Affymetrix probe sets: 10417095 (MoGene1.0st)   1452280_at (Mouse Genome 430 2.0 Array)   1459799_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000116985
Ensembl peptide - ENSMUSP00000026635
NCBI entrez gene - 223254     See in Manteia.
MGI - MGI:2446173
RefSeq - NM_134082
RefSeq - XM_006518914
RefSeq - XM_006518915
RefSeq Peptide - NP_598843
swissprot - F8VPU2
swissprot - E9Q805
Ensembl - ENSMUSG00000025555
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 farp1ENSDARG00000074381Danio rerio
 FARP1ENSGALG00000016886Gallus gallus
 FARP1ENSG00000152767Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Farp2 / Q91VS8 / FERM, ARHGEF and pleckstrin domain-containing protein 2 / O94887* / FERM, ARH/RhoGEF and pleckstrin domain protein 2*ENSMUSG0000003406653
Frmd7 / A2AD83 / FERM domain-containing protein 7 / Q6ZUT3* / FERM domain containing 7*ENSMUSG0000003613125
Rdx / P26043 / radixin / P35241*ENSMUSG0000003205015
Ezr / Ezrin / P26040 / P15311*ENSMUSG0000005239714
Msn / P26041 / Moesin / P26038*ENSMUSG0000003120714
Nf2 / P46662 / Merlin / P35240* / neurofibromin 2*ENSMUSG0000000907312
Mylip / Q8BM54 / E3 ubiquitin-protein ligase MYLIP / Q8WY64* / myosin regulatory light chain interacting protein*ENSMUSG0000003817510


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR000299  FERM domain
 IPR000798  Ezrin/radixin/moesin-like
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR014847  FERM adjacent (FA)
 IPR018979  FERM, N-terminal
 IPR018980  FERM, C-terminal PH-like domain
 IPR019747  FERM conserved site
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR029071  Ubiquitin-like domain superfamily
 IPR035899  Dbl homology (DH) domain superfamily
 IPR035963  FERM superfamily, second domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007416 synapse assembly IEA
 biological_processGO:0010923 negative regulation of phosphatase activity ISO
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0048813 dendrite morphogenesis IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030175 filopodium IEA
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043197 dendritic spine IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0008092 cytoskeletal protein binding IEA
 molecular_functionGO:0030676 Rac guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0048365 Rac GTPase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr