MP:0000116 | abnormal tooth development | "anomalous formation of the teeth" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ntn1Gt(IRESBetageo)1Pgr/Ntn1Gt(IRESBetageo)1Pgr Genetic Background: involves: 129/Sv * C57BL/6 * NMRI
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2+,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
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MP:0000121 | failure of tooth eruption | "inability of the teeth to grow into the oral cavity" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295] |
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Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo
Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0000598 | abnormal liver morphology | "malformation or absence of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:23170] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
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MP:0000599 | enlarged liver | "larger than average size of the liver" [J:65146] |
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Allelic Composition: Cdkn2atm2Brn/Cdkn2atm2Brn,Nf2tm2Gth/Nf2tm2Gth Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Cdkn2atm2Brn/Cdkn2a+,Nf2tm2Gth/Nf2tm2Gth Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53+ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Yap1tm1.1Dupa/Yap1+,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Yap1tm2.1Dupa/Yap1tm2.1Dupa Genetic Background: involves: 129P2/OlaHsd
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MP:0000681 | abnormal thyroid gland morphology | "anomalous structure of the endocrine gland located in the front and to the sides of the upper part of the trachea and which secretes thyroid hormone and calcitonin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Arid1atm1.1Mag/Arid1atm1.1Mag,Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
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MP:0001077 | abnormal spinal nerve morphology | "any anomaly, deformity, or malformation of the any of the 31 paired peripheral nerves formed by the union of the dorsal and ventral spinal roots from each spinal cord segment" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Postn-cre)1Sjc/0 Genetic Background: involves: 129P2/OlaHsd * FVB/NTac
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MP:0001106 | abnormal Schwann cell | "malformed or absent cells which form the insulating myelin sheaths of peripheral axons" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)1Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
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MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Vil-cre)20Syr/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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MP:0001272 | increased metastatic potential | |
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Allelic Composition: Cdkn2atm1.1Brn/Cdkn2a+,Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
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MP:0001303 | abnormal lens morphology | "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
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MP:0001304 | cataracts | "complete or partial opacity of the lens" [J:65031] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Nes-cre)1Kln/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
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MP:0001394 | circling | "repeated, compulsive movement in a circle; often associated with inner ear defects" [MGI:CLS, J:61295] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Postn-cre)1Sjc/0 Genetic Background: involves: 129P2/OlaHsd * FVB/NTac
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MP:0001405 | impaired coordination | "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Fpr2tm1.1Jimw/Fpr2tm1.1Jimw,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129X1/SvJ * C57BL/6J * SJL
Allelic Composition: Nf2tm2Gvn/Nf2+ Genetic Background: Not Specified
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MP:0001410 | head bobbing | "compulsive up and down movement of the head" [J:17123] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Postn-cre)1Sjc/0 Genetic Background: involves: 129P2/OlaHsd * FVB/NTac
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MP:0001512 | trunk curl | "posture of the trunk in a curled position" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Postn-cre)1Sjc/0 Genetic Background: involves: 129P2/OlaHsd * FVB/NTac
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MP:0001522 | impaired swimming | "reduced ability or inability to swim" [J:45446, J:39081] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Postn-cre)1Sjc/0 Genetic Background: involves: 129P2/OlaHsd * FVB/NTac
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MP:0001523 | impaired righting response | "reduced ability or greater amount of time needed to recover from supine position" [J:25565] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Postn-cre)1Sjc/0 Genetic Background: involves: 129P2/OlaHsd * FVB/NTac
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MP:0001683 | absent mesoderm | "missing or failure to differentiate the middle primary germ layer " [J:40594] |
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Allelic Composition: Ntn1Gt(IRESBetageo)1Pgr/Ntn1Gt(IRESBetageo)1Pgr Genetic Background: involves: 129/Sv * C57BL/6 * NMRI
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MP:0001696 | failure to gastrulate | "inability to differentiate and invaginate the primary germ layers" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:34458] |
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Allelic Composition: Ntn1Gt(IRESBetageo)1Pgr/Ntn1Gt(IRESBetageo)1Pgr Genetic Background: involves: 129/Sv * C57BL/6 * NMRI
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MP:0001704 | abnormal dorsal-ventral axis patterning | "anomaly in the development or formation of the axis that runs from the front to the back surface of the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ntn1Gt(IRESBetageo)1Pgr/Ntn1Gt(IRESBetageo)1Pgr Genetic Background: involves: 129/Sv * C57BL/6 * NMRI
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MP:0001711 | abnormal placenta | |
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Allelic Composition: Ntn1Gt(IRESBetageo)1Pgr/Ntn1Gt(IRESBetageo)1Pgr Genetic Background: involves: 129/Sv * C57BL/6 * NMRI
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MP:0001850 | otitis media | "middle ear inflammation" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60896] |
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Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0001891 | hydroencephaly | "excessive accumulation of cerebrospinal fluid in the brain, especially the cerebral ventricles, often leading to increased brain size and other brain trauma" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003] |
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Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brd/Trp53+,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
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MP:0001924 | infertility | "inability to produce live offspring" [J:47225] |
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Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo
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MP:0001973 | increased thermal nociceptive threshold | "a greater than average point at which thermal pain sensation is first detectable" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, J:17194] |
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Allelic Composition: Fpr2tm1.1Jimw/Fpr2tm1.1Jimw,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129X1/SvJ * C57BL/6J * SJL
Allelic Composition: Nf2tm2Gvn/Nf2+ Genetic Background: Not Specified
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MP:0002018 | malignant tumors | "higher than normal incidence of locally invasive, destructive and metastatic tumors " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:44427] |
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Allelic Composition: Ntn1Gt(IRESBetageo)1Pgr/Ntn1Gt(IRESBetageo)1Pgr Genetic Background: involves: 129/Sv * C57BL/6 * NMRI
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MP:0002020 | increased tumor incidence | "greater than average number of tumors, usually a specific type" [MGI:cls, J:34193] |
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Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Cdkn2atm1.1Brn/Cdkn2atm1.1Brn,Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Cdkn2atm2Brn/Cdkn2atm2Brn,Nf2tm2Gth/Nf2tm2Gth Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Cdkn2atm2Brn/Cdkn2atm2Brn,Nf2tm2Gth/Nf2+ Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Cdkn2atm2Brn/Cdkn2a+,Nf2tm2Gth/Nf2tm2Gth Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53+ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Cdkn2atm1.1Brn/Cdkn2a+,Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth Genetic Background: involves: 129P2/OlaHsd
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MP:0002024 | T cell derived lymphoma | "group of heterogeneous lymphoid tumors representing malignant transformations of T-lymphocytes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
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MP:0002026 | leukemia | "progressive proliferation of abnormal leukocytes in hematopoietic tissues, organs and blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18542] |
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Allelic Composition: Cdkn2atm2Brn/Cdkn2atm2Brn,Nf2tm2Gth/Nf2tm2Gth Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Cdkn2atm2Brn/Cdkn2atm2Brn,Nf2tm2Gth/Nf2+ Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Cdkn2atm2Brn/Cdkn2a+,Nf2tm2Gth/Nf2tm2Gth Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53+ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
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MP:0002027 | lung adenocarcinoma | "malignant neoplasm of epithelial cells in the lung" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:18542] |
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Allelic Composition: Ntn1Gt(IRESBetageo)1Pgr/Ntn1Gt(IRESBetageo)1Pgr Genetic Background: involves: 129/Sv * C57BL/6 * NMRI
Allelic Composition: Nf2tm1Gth/Nf2+ Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2.1Gth/Nf2+ Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2+,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0002030 | neurofibrosarcoma | "malignant neoplasm of fibrous tissue of the nervous system" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18542] |
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Allelic Composition: Nf2tm1Gth/Nf2+ Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brd/Trp53+,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Postn-cre)1Sjc/0 Genetic Background: involves: 129P2/OlaHsd * FVB/NTac
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MP:0002032 | sarcoma | "connective tissue neoplasm associated with the proliferation of mesodermal cells" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:58877] |
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Allelic Composition: Ntn1Gt(IRESBetageo)1Pgr/Ntn1Gt(IRESBetageo)1Pgr Genetic Background: involves: 129/Sv * C57BL/6 * NMRI
Allelic Composition: Nf2tm1Gth/Nf2+ Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
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MP:0002035 | leiomyosarcoma | "malignant tumor derived from smooth (nonstriated) muscle" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:58877] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
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MP:0002036 | rhabdomyosarcoma | "malignant tumor derived from skeletal (striated) muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58877] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Cdkn2atm1.1Brn/Cdkn2atm1.1Brn,Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Cdkn2atm2Brn/Cdkn2atm2Brn,Nf2tm2Gth/Nf2tm2Gth Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Cdkn2atm1.1Brn/Cdkn2a+,Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
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MP:0002038 | carcinoma | "malignant neoplasm arising from epithelial cells, usually glandular or squamous" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:58877] |
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Allelic Composition: Ntn1Gt(IRESBetageo)1Pgr/Ntn1Gt(IRESBetageo)1Pgr Genetic Background: involves: 129/Sv * C57BL/6 * NMRI
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MP:0002041 | pituitary adenoma | "appearance of benign neoplasms of the pituitary" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33042] |
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Allelic Composition: Mir146tm2.1Bal/Mir146tm2.1Bal Genetic Background: involves: 129S1/Sv * C57BL/6 * FVB/N
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MP:0002049 | extremity angiosarcoma | "malignant neoplasm of soft tissues; thought to arise from endothelial cells of blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:57631] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
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MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)4Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brd/Trp53+,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Cdkn2atm1.1Brn/Cdkn2atm1.1Brn,Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Cdkn2atm2Brn/Cdkn2atm2Brn,Nf2tm2Gth/Nf2tm2Gth Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Cdkn2atm2Brn/Cdkn2atm2Brn,Nf2tm2Gth/Nf2+ Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Cdkn2atm2Brn/Cdkn2a+,Nf2tm2Gth/Nf2tm2Gth Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53+ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Vil-cre)20Syr/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Ptgdstm1.1(cre)Gvn/Ptgds+,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Postn-cre)1Sjc/0 Genetic Background: involves: 129P2/OlaHsd * FVB/NTac
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MP:0002084 | abnormal developmental patterning | "abnormal systematic arrangement of the developing body along an axis" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ntn1Gt(IRESBetageo)1Pgr/Ntn1Gt(IRESBetageo)1Pgr Genetic Background: involves: 129/Sv * C57BL/6 * NMRI
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MP:0002085 | abnormal embryonic tissue morphology | "structural abnormality or development of any embryonic tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ntn1Gt(IRESBetageo)1Pgr/Ntn1Gt(IRESBetageo)1Pgr Genetic Background: involves: 129/Sv * C57BL/6 * NMRI
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MP:0002086 | abnormal extraembryonic tissue morphology | "structural abnormality or development of the membranes involved with embryonic protection and nutrition" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:40594, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ntn1Gt(IRESBetageo)1Pgr/Ntn1Gt(IRESBetageo)1Pgr Genetic Background: involves: 129/Sv * C57BL/6 * NMRI
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MP:0002582 | disorganized extraembryonic tissue | "a lack of the regular arrangement of the membranes involved with the embryo s protection and nutrition" [J:40596, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ntn1Gt(IRESBetageo)1Pgr/Ntn1Gt(IRESBetageo)1Pgr Genetic Background: involves: 129/Sv * C57BL/6 * NMRI
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MP:0002583 | absent extraembryonic ectoderm | "missing layer of the endoderm of the extraembryonic tissue" [J:40596, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ntn1Gt(IRESBetageo)1Pgr/Ntn1Gt(IRESBetageo)1Pgr Genetic Background: involves: 129/Sv * C57BL/6 * NMRI
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MP:0002584 | small ectoplacental cone | |
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Allelic Composition: Ntn1Gt(IRESBetageo)1Pgr/Ntn1Gt(IRESBetageo)1Pgr Genetic Background: involves: 129/Sv * C57BL/6 * NMRI
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MP:0002703 | abnormal renal tubules | "anomalous structure or development of the loops of Henle and collecting ducts in the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Nf2tm1Gth/Nf2+ Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
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MP:0003053 | delayed tooth eruption | "postponed onset of the growth of the teeth out of the gums" [pvb:Pierre Vanden Borre, Mouse Genome Informatics Curator] |
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Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo
Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0003237 | abnormal lens epithelium morphology | "malformation in the one or more of the layers of epithelial cells in the lens" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93301] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Nes-cre)1Kln/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
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MP:0003252 | abnormal bile duct physiology | "anomalous action or function of the channels that secrete bile from the liver to the gall bladder and intestines" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Yap1tm2.1Dupa/Yap1tm2.1Dupa Genetic Background: involves: 129P2/OlaHsd
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MP:0003255 | bile duct proliferation | "the appearance of an increased number of bile ducts in the liver; a sign of progressive liver disease" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
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MP:0003331 | hepatocellular carcinoma | "malignant neoplasm arising from liver cells" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
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MP:0003570 | uterine leiomyoma | "a benign tumor derived from the smooth muscle tissue of the uterus" [ncbi:Matthew Mailman, NCBI request, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Cdkn2atm2Brn/Cdkn2atm2Brn,Nf2tm2Gth/Nf2tm2Gth Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Cdkn2atm2Brn/Cdkn2atm2Brn,Nf2tm2Gth/Nf2+ Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Cdkn2atm2Brn/Cdkn2a+,Nf2tm2Gth/Nf2tm2Gth Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53+ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
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MP:0003789 | osteosarcoma | "malignant neoplasm derived from bone" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Ntn1Gt(IRESBetageo)1Pgr/Ntn1Gt(IRESBetageo)1Pgr Genetic Background: involves: 129/Sv * C57BL/6 * NMRI
Allelic Composition: Nf2tm1Gth/Nf2+ Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2.1Gth/Nf2+ Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brd/Trp53+,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Ptgdstm1.1(cre)Gvn/Ptgds+,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0004740 | sensorineural hearing loss | "a form of progressive hearing loss due to a lesion of the auditory division of cranial nerve VIII or the inner ear" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Postn-cre)1Sjc/0 Genetic Background: involves: 129P2/OlaHsd * FVB/NTac
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MP:0004839 | bile duct hyperplasia | "overdevelopment or increased size of the bile ducts, usually due to an increase in the number of cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
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MP:0004986 | abnormal osteoblast morphology | "any structural anomaly of a bone-forming cell, which normally forms an osseous matrix (osteoid) in which it becomes enclosed as an osteocyte" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nf2tm1Gth/Nf2+ Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
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MP:0005191 | head tilt | "condition in which the portion of the body containing the brain and organs of sight, hearing, taste, and smell lists to the side" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Postn-cre)1Sjc/0 Genetic Background: involves: 129P2/OlaHsd * FVB/NTac
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MP:0005307 | head tossing | "compulsive flailing of the head in multiple directions" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Postn-cre)1Sjc/0 Genetic Background: involves: 129P2/OlaHsd * FVB/NTac
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MP:0005402 | abnormal action potential | "change in the electric response of a nerve or other excitable tissue to its stimulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Nf2tm2Gvn/Nf2tm2Gvn Genetic Background: Not Specified
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MP:0005404 | abnormal axon morphology | "anomaly in the structure of the single process of a nerve cell that normally conducts impulses away from the cell body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Fpr2tm1.1Jimw/Fpr2tm1.1Jimw,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129X1/SvJ * C57BL/6J * SJL
Allelic Composition: Nf2tm2Gvn/Nf2tm2Gvn Genetic Background: Not Specified
Allelic Composition: Nf2tm2Gvn/Nf2+ Genetic Background: Not Specified
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MP:0005623 | abnormal meninges | "anomaly in any of the membranes covering the spinal cord and brain, including the dura mater (external), arachnoid (middle), and pia mater (internal)" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, smb:Susan M. Bello , Mouse Genome Informatics Curator, J:48079] |
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Allelic Composition: Cdkn2atm1.1Brn/Cdkn2atm1.1Brn,Nf2tm2Gth/Nf2tm2Gth Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0008019 | liver tumor | "presence of abnormal, rapidly proliferating cells in the liver usually in the form of a distinct mass" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cdkn2atm1.1Brn/Cdkn2atm1.1Brn,Nf2tm2Gth/Nf2tm2Gth Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0008490 | enlarged dorsal root ganglion | "increased size a group of sensory nerve cell bodies located on the dorsal spinal roots within the vertebral column" [MESH:A08.340.390.340] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Postn-cre)1Sjc/0 Genetic Background: involves: 129P2/OlaHsd * FVB/NTac
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MP:0008770 | decreased survivor rate | "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)4Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)4Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
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MP:0010280 | increased skeletal tumor incidence | "greater than the expected number of neoplasms in the skeletal tissue, usually in the form of a distinct mass, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brd/Trp53+,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
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MP:0010281 | increased nervous system tumor incidence | "greater than the expected number of tumors originating in the nervous system in a given population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Ptgdstm1.1(cre)Gvn/Ptgds+,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0010297 | increased hepatobiliary system tumor incidence | |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
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MP:0010306 | increased hamartoma incidence | "greater than the expected number of benign focal malformations in a specific population in a given time period; results from faulty development of an organ, and is composed of an abnormal mixture of tissue elements, or an abnormal proportion of a single element normally present at that site" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)1Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Yap1tm2.1Dupa/Yap1tm2.1Dupa Genetic Background: involves: 129P2/OlaHsd
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MP:0010309 | increased mesothelioma incidence | "greater than the expected number of neoplasms derived from the lining cells of the pleura and peritoneum, in a specific population in a given time period; is composed of spindle cells or fibrous tissue which may enclose glandlike spaces lined by cuboidal cells" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Nf2tm1Gth/Nf2+ Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Cdkn2atm1.1Brn/Cdkn2atm1.1Brn,Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53+ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Cdkn2atm1.1Brn/Cdkn2a+,Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
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MP:0010310 | increased Schwannoma incidence | "greater than the expected number of benign, encapsulated nerve sheath tumors composed of Schwann cells, in a specific population in a given time period; usually associated with a peripheral or cranial nerve" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)4Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Cdkn2atm1.1Brn/Cdkn2atm1.1Brn,Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53+ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Postn-cre)1Sjc/0 Genetic Background: involves: 129P2/OlaHsd * FVB/NTac
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MP:0010311 | increased meningioma incidence | "greater than the expected number of encapsulated neoplasms derived from the meninges, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cdkn2atm1.1Brn/Cdkn2atm1.1Brn,Nf2tm2Gth/Nf2tm2Gth Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Ptgdstm1.1(cre)Gvn/Ptgds+ Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Cdkn2atm1.1Brn/Cdkn2atm1.1Brn,Nf2tm2Gth/Nf2tm2Gth,Ptgdstm1.1(cre)Gvn/Ptgds+ Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0010313 | increased osteoma incidence | "greater than the expected number of benign neoplasms derived from lamellar bone, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nf2tm1Gth/Nf2+ Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2.1Gth/Nf2+ Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2+,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brd/Trp53+,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Cdkn2atm1.1Brn/Cdkn2atm1.1Brn,Nf2tm2Gth/Nf2tm2Gth Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Ptgdstm1.1(cre)Gvn/Ptgds+ Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0010314 | increased neurofibroma incidence | "greater than the expected number of benign, encapsulated nerve sheath tumors composed of Schwann cells, in a specific population in a given time period; proliferation is disordered and includes portions of nerve fibers" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nf2tm1Gth/Nf2+ Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
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MP:0010316 | increased thyroid tumor incidence | "greater than the expected number of neoplams in the thyroid occurring in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Arid1atm1.1Mag/Arid1atm1.1Mag,Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
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MP:0010334 | pleural effusion | "accumulation of excess fluid in the pleural cavity" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cdkn2atm1.1Brn/Cdkn2a+,Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
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MP:0010347 | osseous metaplasia | "the formation of mature bone elements in the stroma of a neoplasm" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nf2tm1Gth/Nf2+ Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N
Allelic Composition: Cdkn2atm1.1Brn/Cdkn2atm1.1Brn,Nf2tm2Gth/Nf2tm2Gth Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0010353 | increased odontoma incidence | "greater than the expected number of a hamartomatous odontogenic tumor composed of enamel, dentin, cementum, and pulp tissue that may or may not be arranged in the form of a tooth, occurring in a specific population in a given time period" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0010354 | increased odontosarcoma incidence | "greater than the expected number of an a gnathic malignant connective tissue tumor in which the epithelial component is benign and the proliferative mesenchymal component is malignant, occurring in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:10587276] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0010363 | increased fibrosarcoma incidence | "greater than the expected number of a highly aggressive malignant neoplasm arising from fibrous connective tissue, in a specific population in a given time period" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ntn1Gt(IRESBetageo)1Pgr/Ntn1Gt(IRESBetageo)1Pgr Genetic Background: involves: 129/Sv * C57BL/6 * NMRI
Allelic Composition: Nf2tm2.1Gth/Nf2+ Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0010364 | increased fibroadenoma incidence | "greater than the expected number of a benign mammary gland tumor composed of both fibrous tissue and glandular tissue, in a specific population in a given time period" [CDR:523438 "http://www.cancer.gov/dictionary/?CdrID=523438"] |
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Allelic Composition: Nf2tm1Gth/Nf2+ Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2+,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0010384 | increased renal carcinoma incidence | "greater than the expected number of malignant neoplasms arising from kidney epithelial tissue, occurring in a specific population in a given time period" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Nf2tm1Gth/Nf2+ Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)3Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)#Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Vil-cre)20Syr/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
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MP:0010742 | increased Schwann cell number | "greater than normal number of cells that sheath the axons of the peripheral nervous system" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Postn-cre)1Sjc/0 Genetic Background: involves: 129P2/OlaHsd * FVB/NTac
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MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Nf2tm1Gth/Nf2tm2Gth,Tg(P0-Cre)1Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(P0-Cre)2Gth/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Vil-cre)20Syr/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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MP:0011090 | partial perinatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Vil-cre)20Syr/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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MP:0011092 | complete embryonic lethality | "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith] |
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Allelic Composition: Nf2tm1Gth/Nf2+ Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Nf2tm2.1Gth/Nf2tm2.1Gth Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0011106 | partial embryonic lethality before somite formation | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith] |
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Allelic Composition: Ntn1Gt(IRESBetageo)1Pgr/Ntn1Gt(IRESBetageo)1Pgr Genetic Background: involves: 129/Sv * C57BL/6 * NMRI
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MP:0011109 | partial lethality throughout fetal growth and development | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Vil-cre)20Syr/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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MP:0011186 | abnormal visceral endoderm morphology | "any structural anomaly of the primitive endoderm-derived tissue which remains in contact with and surrounds the extra-embryonic ectoderm and the epiblast and provides signals for the differentiation and patterning of the epiblast; a small number of visceral endoderm cells also contribute to the endoderm of the embryonic gut" [PMID:21123814] |
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Allelic Composition: Ntn1Gt(IRESBetageo)1Pgr/Ntn1Gt(IRESBetageo)1Pgr Genetic Background: involves: 129/Sv * C57BL/6 * NMRI
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MP:0011966 | abnormal auditory brainstem response waveform shape | "any anomaly in the characteristic pattern of electrical activity recording of a series of vertex positive waves generated by neurons in the ascending auditory system, that can be recorded from scalp electrograms by using computer-averaged responses to short tone bursts" [MGI:csmith] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Postn-cre)1Sjc/0 Genetic Background: involves: 129P2/OlaHsd * FVB/NTac
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MP:0011967 | increased or absent threshold for auditory brainstem response | "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Tg(Postn-cre)1Sjc/0 Genetic Background: involves: 129P2/OlaHsd * FVB/NTac
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MP:0012431 | increased lymphoma incidence | "greater than the expected number of neoplasms characterized by a proliferation of malignant lymphocytes in lymphoid tissue in a specific population in a given time period" [http://orcid.org/0000-0001-5208-3432, MGI:csmith] |
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Allelic Composition: Ntn1Gt(IRESBetageo)1Pgr/Ntn1Gt(IRESBetageo)1Pgr Genetic Background: involves: 129/Sv * C57BL/6 * NMRI
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MP:0013611 | abnormal bile duct epithelium morphology | "any structural anomaly of the epithelium lining the intrahepatic and extrahepatic bile ducts" [MGI:Anna] |
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Yap1tm2.1Dupa/Yap1tm2.1Dupa Genetic Background: involves: 129P2/OlaHsd
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