ENSDARG00000028192


Danio rerio

Features
Gene ID: ENSDARG00000028192
  
Biological name :cradd
  
Synonyms : CASP2 and RIPK1 domain containing adaptor with death domain / cradd
  
Possible biological names infered from orthology : Mus musculus CASP2 and RIPK1 domain containing adaptor with death domain (Cradd), transcript variant 3, mRNA. / O88843 / P78560
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 18383253
Gene end: 18416566
  
Corresponding Affymetrix probe sets: DrAffx.2.106.A1_at (Zebrafish Array)   DrAffx.2.106.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000038654
NCBI entrez gene - 450046     See in Manteia.
swissprot - Q5XJP2
ZFIN ID - ZDB-GENE-041010-168
Ensembl - ENSDARG00000028192
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CRADDENSGALG00000011297Gallus gallus
 CRADDENSG00000169372Homo sapiens
 CraddENSMUSG00000045867Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000488  Death domain
 IPR001315  CARD domain
 IPR011029  Death-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 molecular_functionGO:0002020 protease binding IEA
 molecular_functionGO:0070513 death domain binding IEA


Pathways (from Reactome)
Pathway description
TP53 Regulates Transcription of Caspase Activators and Caspases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000062052 casp2 / caspase 2, apoptosis-related cysteine peptidase / P42575* / P29594* / caspase 2* / Caspase-2 Caspase-2 subunit p18 Caspase-2 subunit p13 Caspase-2 subunit p12*  / complex / reaction
 ENSDARG00000028192 cradd / CASP2 and RIPK1 domain containing adaptor with death domain / O88843* / P78560* / Mus musculus CASP2 and RIPK1 domain containing adaptor with death domain (Cradd), transcript varian...  / reaction / complex
 ENSDARG00000074626 pidd1 / p53-induced death domain protein 1 / Q9ERV7* / Q9HB75* / p53-induced death domain-containing protein 1 *  / reaction / complex






 

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contact: otassy@igbmc.fr