ENSDARG00000074626


Danio rerio

Features
Gene ID: ENSDARG00000074626
  
Biological name :pidd1
  
Synonyms : p53-induced death domain protein 1 / pidd1
  
Possible biological names infered from orthology : p53-induced death domain-containing protein 1 / Q9ERV7 / Q9HB75
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 4507288
Gene end: 4530085
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000122836
Ensembl peptide - ENSDARP00000147993
NCBI entrez gene - 571033     See in Manteia.
swissprot - E9QFQ1
ZFIN ID - ZDB-GENE-081104-353
Ensembl - ENSDARG00000074626
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PIDD1ENSGALG00000040729Gallus gallus
 PIDD1ENSG00000177595Homo sapiens
 Pidd1ENSMUSG00000025507Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
lrch2 / leucine-rich repeats and calponin homology (CH) domain containing 2 / Q3UMG5* / Q5VUJ6* / leucine rich repeats and calponin homology domain containing 2* / Leucine-rich repeat and c...ENSDARG0000007558012
lrch4 / leucine-rich repeats and calponin homology (CH) domain containing 4 / Q921G6* / O75427* / Gm20605* / predicted gene 20605* / leucine rich repeats and calponin homology domain contai...ENSDARG0000006825812
lrch1 / leucine-rich repeats and calponin homology (CH) domain containing 1 / P62046* / Q9Y2L9* / leucine rich repeats and calponin homology domain containing 1* / Leucine-rich repeat and c...ENSDARG0000007877812
lrch3 / leucine-rich repeats and calponin homology (CH) domain containing 3 / Q8BVU0* / Q96II8* / leucine rich repeats and calponin homology domain containing 3* / Leucine-rich repeat and c...ENSDARG000001006798
F1R6I3 / lrrc39 / leucine rich repeat containing 39 / Q96DD0* / Q8BGI7* / Leucine-rich repeat-containing protein 39 *ENSDARG000000714658
lrrc18a / leucine rich repeat containing 18a / Q9CQ07* / LRRC18* / Q8N456* / leucine rich repeat containing 18* / Leucine-rich repeat-containing protein 18 *ENSDARG000000787908
lrrc28 / leucine rich repeat containing 28 / Q86X40*ENSDARG000000574778
lrrc18b / leucine rich repeat containing 18b / Q9CQ07* / LRRC18* / Q8N456* / leucine rich repeat containing 18* / Leucine-rich repeat-containing protein 18 *ENSDARG000000762368
lrrc57 / Q6DHL5 / leucine rich repeat containing 57 / Q8N9N7* / leucine-rich repeat-containing protein 57 isoform a *ENSDARG000000439387
LRRC8E / si:zfos-323e3.4 / Q6NSJ5* / Q66JT1* / AC093423.3* / Volume-regulated anion channel subunit LRRC8E * / leucine rich repeat containing 8 VRAC subunit E*ENSDARG000000782837
LRRC69 / si:ch73-302o18.2 / Q6ZNQ3* / Q9D9Q0* / leucine rich repeat containing 69* / Leucine-rich repeat-containing protein 69 *ENSDARG000000883167
lrsam1 / leucine rich repeat and sterile alpha motif containing 1 / Q6UWE0* / Q80ZI6* / E3 ubiquitin-protein ligase LRSAM1 *ENSDARG000000606836
lrrc8da / leucine rich repeat containing 8 VRAC subunit Da / LRRC8D* / Q7L1W4* / Q8BGR2* / Volume-regulated anion channel subunit LRRC8D * / leucine rich repeat containing 8 VRAC subunit D*ENSDARG000001033706
si:dkey-1h4.4ENSDARG000001055486
si:ch211-106h11.1ENSDARG000000177206
lrrc8c / leucine rich repeat containing 8 VRAC subunit C / Q8R502* / Q8TDW0* / Volume-regulated anion channel subunit LRRC8C *ENSDARG000000999116
lrrc8ab / leucine rich repeat containing 8 VRAC subunit Ab / Q8IWT6* / LRRC8A* / Q80WG5* / Gm28035* / predicted gene, 28035* / Volume-regulated anion channel subunit LRRC8A * / leucine rich...ENSDARG000000521555
lrrc8aa / leucine rich repeat containing 8 VRAC subunit Aa / Q8IWT6* / LRRC8A* / Q80WG5* / Gm28035* / predicted gene, 28035* / Volume-regulated anion channel subunit LRRC8A * / leucine rich...ENSDARG000000321885
lrrc8db / leucine rich repeat containing 8 VRAC subunit Db / LRRC8D* / Q7L1W4* / Q8BGR2* / Volume-regulated anion channel subunit LRRC8D * / leucine rich repeat containing 8 VRAC subunit D*ENSDARG000001038405
rsu1 / Ras suppressor protein 1 / Q15404*ENSDARG000001028855


Protein motifs (from Interpro)
Interpro ID Name
 IPR000488  Death domain
 IPR000906  ZU5 domain
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR011029  Death-like domain superfamily
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IBA
 cellular_componentGO:0005886 plasma membrane IBA


Pathways (from Reactome)
Pathway description
TP53 Regulates Transcription of Caspase Activators and Caspases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000002385 atm / ATM serine/threonine kinase / Q13315* / Q62388* / Serine-protein kinase ATM *  / reaction
 ENSDARG00000028192 cradd / CASP2 and RIPK1 domain containing adaptor with death domain / O88843* / P78560* / Mus musculus CASP2 and RIPK1 domain containing adaptor with death domain (Cradd), transcript varian...  / complex / reaction
 ENSDARG00000074626 pidd1 / p53-induced death domain protein 1 / Q9ERV7* / Q9HB75* / p53-induced death domain-containing protein 1 *  / complex / reaction
 ENSDARG00000062052 casp2 / caspase 2, apoptosis-related cysteine peptidase / P42575* / P29594* / caspase 2* / Caspase-2 Caspase-2 subunit p18 Caspase-2 subunit p13 Caspase-2 subunit p12*  / reaction / complex






 

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